(Q39560559)

13 September 2017

In Silico Mining for Antimalarial Structure-Activity Knowledge and Discovery of Novel Antimalarial Curcuminoids (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

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5

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Elisabeth Davioud-Charvet

13 May 2020

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

Thibault Gendron

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

Sandrine Cojean

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

Gilles Marcou

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

Uko Maran

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

author name string

Birgit Viira

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

Don Antoine Lanfranchi

3

1 reference

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13 May 2020

Alexandre Varnek

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

Louis Maes

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

Philippe M Loiseau

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

language of work or name

English

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publication date

29 June 2016

1 reference

13 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

Creative Commons Attribution 4.0 International

13 May 2020

copyright license

start time

29 June 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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21 January 2018

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Glutathione – Functions and Metabolism in the Malarial Parasite Plasmodium falciparum

21 January 2018

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Low-molecular-mass antioxidants in parasites.

21 January 2018

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Detection of thiol-based redox switch processes in parasites - facts and future

21 January 2018

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The redox systems of Plasmodium falciparum and Plasmodium vivax: comparison, in silico analyses and inhibitor studies

21 January 2018

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Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action

21 January 2018

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Glutathione is involved in the antimalarial action of chloroquine and its modulation affects drug sensitivity of human and murine species of Plasmodium

21 January 2018

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Glutathione transport: a new role for PfCRT in chloroquine resistance

21 January 2018

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Role and Regulation of Glutathione Metabolism in Plasmodium falciparum

21 January 2018

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The thioredoxin system of the malaria parasite Plasmodium falciparum. Glutathione reduction revisited.

21 January 2018

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Identification of proteins targeted by the thioredoxin superfamily in Plasmodium falciparum

21 January 2018

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Thioredoxin reductase is essential for the survival of Plasmodium falciparum erythrocytic stages

21 January 2018

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Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents.

21 January 2018

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Mechanism-based inactivation of thioredoxin reductase from Plasmodium falciparum by Mannich bases. Implication for cytotoxicity

21 January 2018

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Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity

21 January 2018

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The aza-analogues of 1,4-naphthoquinones are potent substrates and inhibitors of plasmodial thioredoxin and glutathione reductases and of human erythrocyte glutathione reductase

21 January 2018

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Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases

21 January 2018

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A sugar-modified phosphole gold complex with antiproliferative properties acting as a thioredoxin reductase inhibitor in MCF-7 cells

21 January 2018

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Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs

21 January 2018

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The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis.

21 January 2018

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Determination of antiplasmodial activity and binding affinity of curcumin and demethoxycurcumin towards PfTrxR.

21 January 2018

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Curcumin enhances non-opsonic phagocytosis of Plasmodium falciparum through up-regulation of CD36 surface expression on monocytes/macrophages

21 January 2018

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Curcumin-artemisinin combination therapy for malaria

21 January 2018

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Dibenzylideneacetone analogues as novel Plasmodium falciparum inhibitors

21 January 2018

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Curcumin--from molecule to biological function.

21 January 2018

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Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups

21 January 2018

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Anti-oxidant activities of curcumin and related enones

21 January 2018

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Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia.

21 January 2018

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A novel monocarbonyl analogue of curcumin, (1E,4E)-1,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one, induced cancer cell H460 apoptosis via activation of endoplasmic reticulum stress signaling pathway

21 January 2018

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Curcumin for malaria therapy

21 January 2018

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Synthesis and exploration of novel curcumin analogues as anti-malarial agents

21 January 2018

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Synthesis, antimalarial activity and cytotoxic potential of new monocarbonyl analogues of curcumin

21 January 2018

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Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum

21 January 2018

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Unsaturated Mannich bases active against multidrug-resistant Trypanosoma brucei brucei strains

21 January 2018

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Novel in vivo active anti-malarials based on a hydroxy-ethyl-amine scaffold.

21 January 2018

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Antimalarial versus cytotoxic properties of dual drugs derived from 4-aminoquinolines and Mannich bases: interaction with DNA.

21 January 2018

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Catalytic Asymmetric Synthesis of Antimalarial Alkaloids Febrifugine and Isofebrifugine and Their Biological Activity.

21 January 2018

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Mannich bases in medicinal chemistry and drug design.

21 January 2018

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Thousands of chemical starting points for antimalarial lead identification

21 January 2018

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CERAPP: Collaborative Estrogen Receptor Activity Prediction Project

21 January 2018

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Mappability of drug-like space: towards a polypharmacologically competent map of drug-relevant compounds

21 January 2018

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ISIDA Property-Labelled Fragment Descriptors.

21 January 2018

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Human malaria parasites in continuous culture

21 January 2018

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Synchronization of Plasmodium falciparum Erythrocytic Stages in Culture

21 January 2018

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Modeling of ion complexation and extraction using substructural molecular fragments

21 January 2018

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12 December 2020

Pigment biocrystallization in Plasmodium falciparum

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12 December 2020

Aminoalkylphenols as antimalarials (heterocyclicamino)-alpha-amino-o-cresols; the synthesis of camoquin

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12 December 2020

Predicting the Predictability: A Unified Approach to the Applicability Domain Problem of QSAR Models

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12 December 2020

Inhibition of P. falciparum PFATP6 by curcumin and its derivatives: a bioinformatic study.

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12 December 2020

Laboratory studies on amopyroquin (propoquin), an antimalarial compound.

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12 December 2020

Synthesis of 7351, a new antimalarial drug (author's transl)

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12 December 2020

The chemotherapy of rodent malaria, XXXVIII. Studies on the activity of three new antimalarials (WR 194,965, WR 228,258 and WR 225,448) against rodent and human malaria parasites (Plasmodium berghei and P. falciparum).

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12 December 2020

10.3390/MOLECULES21070853

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6273176&resulttype=core&format=json

13 May 2020

1 reference