(Q39567618)

13 September 2017

New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis (English)

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13 September 2017

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2

Oliver Eickelberg

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13 September 2017

Isis E Fernandez

1

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PubMed ID

22901889

13 September 2017

language of work or name

English

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publication date

1 August 2012

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13 September 2017

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13 September 2017

380

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13 September 2017

9842

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13 September 2017

680-688

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Update in diffuse parenchymal lung disease 2009.

13 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Smoking and idiopathic pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

High prevalence of abnormal acid gastro-oesophageal reflux in idiopathic pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Gastroesophageal reflux therapy is associated with longer survival in patients with idiopathic pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Is idiopathic pulmonary fibrosis an environmental disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Detection of herpes simplex virus type-1 in patients with fibrotic lung diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Integrating mechanisms of pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

WNT signaling in lung disease: a failure or a regeneration signal?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Epithelial repair mechanisms in the lung

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Idiopathic pulmonary fibrosis

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https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

The pathogenesis of idiopathic pulmonary fibrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

New mechanisms of pulmonary fibrosis

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https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

1 reference

7 January 2021

Histologic spectrum of idiopathic interstitial pneumonias

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Idiopathic pulmonary fibrosis/usual interstitial pneumonia: imaging diagnosis, spectrum of abnormalities, and temporal progression

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Murine models of pulmonary fibrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Fibroblast foci are not discrete sites of lung injury or repair: the fibroblast reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Quantitative analysis of fibroblastic foci in usual interstitial pneumonia.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Fibroblastic foci in usual interstitial pneumonia: idiopathic versus collagen vascular disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Apoptosis and epithelial injury in the lungs

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https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

The critical role of TAK1 in accentuated epithelial to mesenchymal transition in obliterative bronchiolitis after lung transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

SNAI transcription factors mediate epithelial-mesenchymal transition in lung fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Twist: a regulator of epithelial-mesenchymal transition in lung fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Hyaluronan: from extracellular glue to pericellular cue.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

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https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Increased deposition of chondroitin/dermatan sulfate glycosaminoglycan and upregulation of β1,3-glucuronosyltransferase I in pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Pericytes: developmental, physiological, and pathological perspectives, problems, and promises

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Platelet-derived growth factor-beta receptor activation is essential for fibroblast and pericyte recruitment during cutaneous wound healing.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Cellular and molecular mechanisms of renal fibrosis

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https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney

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https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis

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https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Hedgehog-Gli pathway activation during kidney fibrosis

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https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

A pericyte origin of spinal cord scar tissue

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https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

A crosstalk between the Smad and JNK signaling in the TGF-β-induced epithelial-mesenchymal transition in rat peritoneal mesothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Platelet derived growth factor B and epithelial mesenchymal transition of peritoneal mesothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Pleural mesothelial cell transformation into myofibroblasts and haptotactic migration in response to TGF-beta1 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Parenchymal trafficking of pleural mesothelial cells in idiopathic pulmonary fibrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Idiopathic pulmonary fibrosis: aberrant recapitulation of developmental programs?

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https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

FIZZ1 stimulation of myofibroblast differentiation

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https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Notch1 signaling in FIZZ1 induction of myofibroblast differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Sonic hedgehog signaling mediates epithelial-mesenchymal communication and promotes renal fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Oxidative damage and TGF-β differentially induce lung epithelial cell sonic hedgehog and tenascin-C expression: implications for the regulation of lung remodelling in idiopathic interstitial lung disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Modulation of bleomycin-induced lung fibrosis by serotonin receptor antagonists in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Lysophosphatidic acid prevents apoptosis in fibroblasts via G(i)-protein-mediated activation of mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Prostaglandin E2 and the pathogenesis of pulmonary fibrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Diminished prostaglandin E2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Prostaglandin E2 as an inhibitory modulator of fibrogenesis in human lung allografts

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Prostaglandin E₂ protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Matrix crosslinking forces tumor progression by enhancing integrin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment

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https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Modulation of lysyl oxidase-like 2 enzymatic activity by an allosteric antibody inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Transglutaminases: crosslinking enzymes with pleiotropic functions

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Transglutaminase 2 and its role in pulmonary fibrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Tissue stiffness, latent TGF-beta1 activation, and mechanical signal transduction: implications for the pathogenesis and treatment of fibrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

MicroRNAs and cardiac pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

MicroRNAs as mediators and therapeutic targets in chronic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

MicroRNAs and the regulation of fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Inhibition and role of let-7d in idiopathic pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Participation of miR-200 in pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Autophagy in pulmonary diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Autophagy: a core cellular process with emerging links to pulmonary disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Autophagic proteins: new facets of the oxygen paradox

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

TLR4 activity is required in the resolution of pulmonary inflammation and fibrosis after acute and chronic lung injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Autophagy in idiopathic pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Human lung stem cells: oh, the places you'll go!

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

A single cell functions as a tissue-specific stem cell and the in vitro niche-forming cell

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Basal cells as stem cells of the mouse trachea and human airway epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

Notch-dependent differentiation of adult airway basal stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2961144-1

7 January 2021

10.1016/S0140-6736(12)61144-1

Identifiers

DOI

1 reference

13 September 2017

1 reference

PubMed ID

22901889