(Q39570726)

English

Small interfering RNA targeting HIF-1α reduces hypoxia-dependent transcription and radiosensitizes hypoxic HT 1080 human fibrosarcoma cells in vitro

scientific article published on 25 March 2011

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scholarly article

1 reference

Europe PubMed Central

13 September 2017

Small interfering RNA targeting HIF-1α reduces hypoxia-dependent transcription and radiosensitizes hypoxic HT 1080 human fibrosarcoma cells in vitro (English)

1 reference

Europe PubMed Central

13 September 2017

0 references

Michael Flentje

8

object named as

Michael Flentje

1 reference

Europe PubMed Central

13 September 2017

Juergen Loeffler

3

object named as

Juergen Loeffler

1 reference

Europe PubMed Central

13 September 2017

author name string

Adrian Staab

1

1 reference

Europe PubMed Central

13 September 2017

Markus Fleischer

2

1 reference

Europe PubMed Central

13 September 2017

Harun M Said

4

1 reference

Europe PubMed Central

13 September 2017

Astrid Katzer

5

1 reference

Europe PubMed Central

13 September 2017

Christian Plathow

6

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Europe PubMed Central

13 September 2017

Herrmann Einsele

7

1 reference

Europe PubMed Central

13 September 2017

Dirk Vordermark

9

1 reference

Europe PubMed Central

13 September 2017

publication date

25 March 2011

1 reference

Europe PubMed Central

13 September 2017

Strahlentherapie und Onkologie

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Europe PubMed Central

13 September 2017

187

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Europe PubMed Central

13 September 2017

4

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Europe PubMed Central

13 September 2017

252-259

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Europe PubMed Central

13 September 2017

https://scigraph.springernature.com/pub.10.1007/s00066-011-2167-0

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Detection and specific targeting of hypoxic regions within solid tumors: current preclinical and clinical strategies

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Single-arm phase II study of conformal radiation therapy and temozolomide plus fractionated stereotactic conformal boost in high-grade gliomas: final report.

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Prognostic impact of HIF-1alpha expression in patients with definitive radiotherapy for cervical cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Silencing of hypoxia inducible factor-1alpha by RNA interference attenuates human glioma cell growth in vivo.

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Hypoxia-inducible factor-1alpha expression in the gastric carcinogenesis sequence and its prognostic role in gastric and gastro-oesophageal adenocarcinomas

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Hypoxia--a key regulatory factor in tumour growth

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Immunohistochemical Detection of HIF-1α and CAIX in Advanced Head-and-Neck Cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Hypoxia-inducible factor-1alpha is a critical mediator of hypoxia induced apoptosis in cardiac H9c2 and kidney epithelial HK-2 cells

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

HIF-1 and tumour radiosensitivity

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Evaluation of HIF-1 inhibitors as anticancer agents

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Development of a hypoxia-responsive vector for tumor-specific gene therapy

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Hypoxia induced expression of endogenous markers in vitro is highly influenced by pH.

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Effects of HIF-1 inhibition by chetomin on hypoxia-related transcription and radiosensitivity in HT 1080 human fibrosarcoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Modulation of glucose metabolism inhibits hypoxic accumulation of hypoxia-inducible factor-1alpha (HIF-1alpha).

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Inhibition of tumor cell growth in the liver by RNA interference-mediated suppression of HIF-1alpha expression in tumor cells and hepatocytes

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

HIF-1alpha and CA IX staining in invasive breast carcinomas: prognosis and treatment outcome.

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Hypoxia in cancer: significance and impact on clinical outcome

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Cell type-specific association of hypoxia-inducible factor-1 alpha (HIF-1 alpha) protein accumulation and radiobiologic tumor hypoxia

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Green fluorescent protein is a suitable reporter of tumor hypoxia despite an oxygen requirement for chromophore formation

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Endogenous markers of tumor hypoxia predictors of clinical radiation resistance?

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Long-term outcome of mitomycin C- and 5-FU-based primary radiochemotherapy for esophageal cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Enhanced response to radiotherapy in tumours deficient in the function of hypoxia-inducible factor-1

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

The effect of HIF-1alpha siRNA on growth and chemosensitivity of MIA-paca cell line

1 reference

https://api.crossref.org/works/10.1007%2FS00066-011-2167-0

21 January 2018

Cellular signaling and potential new treatment targets in diabetic retinopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21437769

12 December 2020

based on heuristic

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Three-Gene Prognostic Classifier for Early-Stage Non–Small-Cell Lung Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21437769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1alpha.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21437769

12 December 2020

based on heuristic

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Expression of hypoxia-inducible factor-1alpha in esophageal squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21437769

12 December 2020

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[Human recombinant erythropoietin-alpha increases the efficacy of irradiation in preclinical model]

1 reference

https://pubmed.ncbi.nlm.nih.gov/21437769

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Downstaging of pancreatic carcinoma after neoadjuvant chemoradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21437769

12 December 2020

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Expression of hypoxia-inducible factor-1alpha: a novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21437769

12 December 2020

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Non-small cell lung cancer in stages I-IIIB: Long-term results of definitive radiotherapy with doses ≥ 80 Gy in standard fractionation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21437769

12 December 2020

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Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21437769

12 December 2020

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Identifiers

10.1007/S00066-011-2167-0

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

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0 references

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