(Q39573234)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936238%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor (English)

1 reference

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20 March 2020

13

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20 March 2020

Stefan Kaluz

3

1 reference

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20 March 2020

author name string

Qi Shi

1

1 reference

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20 March 2020

Shaoman Yin

2

1 reference

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20 March 2020

Nanting Ni

4

1 reference

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20 March 2020

Narra Sarojini Devi

5

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20 March 2020

Jiyoung Mun

6

1 reference

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20 March 2020

Danzhu Wang

7

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20 March 2020

Krishna Damera

8

1 reference

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20 March 2020

Weixuan Chen

9

1 reference

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20 March 2020

Sarah Burroughs

10

1 reference

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20 March 2020

Suazette Reid Mooring

11

1 reference

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20 March 2020

Mark M Goodman

12

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20 March 2020

Binghe Wang

14

1 reference

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20 March 2020

James P Snyder

15

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20 March 2020

publication date

21 June 2012

1 reference

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ACS Medicinal Chemistry Letters

20 March 2020

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

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20 March 2020

volume

3

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20 March 2020

issue

8

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20 March 2020

page(s)

620-625

1 reference

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KCN1, a novel synthetic sulfonamide anticancer agent: in vitro and in vivo anti-pancreatic cancer activities and preclinical pharmacology

20 March 2020

cites work

1 reference

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Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Structure-activity relationship of 2,2-dimethyl-2H-chromene based arylsulfonamide analogs of 3,4-dimethoxy-N-[(2,2-dimethyl-2H-chromen-6-yl)methyl]-N-phenylbenzenesulfonamide, a novel small molecule hypoxia inducible factor-1 (HIF-1) pathway [...]

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Hypoxia-inducible factors in physiology and medicine

14 September 2017

1 reference

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Design and synthesis of novel small-molecule inhibitors of the hypoxia inducible factor pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Emerging role of surface plasmon resonance in fragment-based drug discovery.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Surface plasmon resonance for proteomics

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Identification of a novel small molecule HIF-1alpha translation inhibitor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Severe hypoxia induces chemo-resistance in clinical cervical tumors through MVP over-expression.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Targeted cancer gene therapy using a hypoxia inducible factor dependent oncolytic adenovirus armed with interleukin-4

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Inhibitors of hypoxia-inducible factor-1 signaling.

14 September 2017

1 reference

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Proteasomal inhibition attenuates transcriptional activity of hypoxia-inducible factor 1 (HIF-1) via specific effect on the HIF-1alpha C-terminal activation domain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Hypoxia inducible factor-1: a novel target for cancer therapy

14 September 2017

1 reference

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Surface plasmon resonance: applications in understanding receptor-ligand interaction

14 September 2017

1 reference

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Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Genetic and hypoxic regulation of angiogenesis in gliomas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma

14 September 2017

1 reference

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Genetic modulation of hypoxia induced gene expression and angiogenesis: relevance to brain tumors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Molecular mechanism of hypoxia-inducible factor 1alpha -p300 interaction. A leucine-rich interface regulated by a single cysteine

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

An essential role for p300/CBP in the cellular response to hypoxia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Engineering human tumor-specific cytotoxic T cells to function in a hypoxic environment

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

Cancer therapy with a replicating oncolytic adenovirus targeting the hypoxic microenvironment of tumors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056939

21 August 2018

Identifiers

DOI

10.1021/ML300042K

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936238%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

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20 March 2020

PubMed publication ID

24936238

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936238%20AND%20SRC:MED&resulttype=core&format=json