(Q37130170)

English

Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents

scientific article published on 24 July 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

0 references

Erwin G. Van Meir

9

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

author name string

Jiyoung Mun

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Adnan Abdul Jabbar

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Narra Sarojini Devi

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Shaoman Yin

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Yingzhe Wang

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Chalet Tan

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Deborah Culver

7

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

James P Snyder

8

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Europe PubMed Central

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18 August 2017

Mark M Goodman

10

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Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

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publication date

24 July 2012

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Europe PubMed Central

PMC publication ID

18 August 2017

Journal of Medicinal Chemistry

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Europe PubMed Central

PMC publication ID

18 August 2017

55

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Europe PubMed Central

PMC publication ID

18 August 2017

15

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

6738-6750

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor.

1 reference

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1 reference

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Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP.

1 reference

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Structure-activity relationship of 2,2-dimethyl-2H-chromene based arylsulfonamide analogs of 3,4-dimethoxy-N-[(2,2-dimethyl-2H-chromen-6-yl)methyl]-N-phenylbenzenesulfonamide, a novel small molecule hypoxia inducible factor-1 (HIF-1) pathway [...]

1 reference

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HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

1 reference

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Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors

1 reference

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1 reference

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Epidithiodiketopiperazines block the interaction between hypoxia-inducible factor-1alpha (HIF-1alpha) and p300 by a zinc ejection mechanism

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Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

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HIF-1alpha determines the metastatic potential of gastric cancer cells

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Hypoxia inducible factor-1alpha inactivation unveils a link between tumor cell metabolism and hypoxia-induced cell death

1 reference

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Evaluation of HIF-1 inhibitors as anticancer agents

1 reference

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Targeted cancer gene therapy using a hypoxia inducible factor dependent oncolytic adenovirus armed with interleukin-4

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Inhibitors of hypoxia-inducible factor-1 signaling.

1 reference

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Inhibiting hypoxia-inducible factor 1 for cancer therapy

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Virtual Computational Chemistry Laboratory – Design and Description

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Hypoxia inducible factor-1: a novel target for cancer therapy

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Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis

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Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway

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Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

1 reference

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Tumor-specific gene expression using the survivin promoter is further increased by hypoxia

1 reference

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HIF-1 as a target for drug development

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

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based on heuristic

inferred from PubMed ID database lookup

A convenient preparation of heteroaryl sulfonamides and sulfonyl fluorides from heteroaryl thiols

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Computing chemistry on the web

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM300752N

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

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