(Q40019570)

16 September 2017

title

Engineering human tumor-specific cytotoxic T cells to function in a hypoxic environment (English)

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16 September 2017

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5

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16 September 2017

6

Malcolm K Brenner

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16 September 2017

7

Patricia Yotnda

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16 September 2017

Hongsung Kim

1

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16 September 2017

Guangyong Peng

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2

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16 September 2017

John M Hicks

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3

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16 September 2017

Heidi L Weiss

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4

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16 September 2017

publication date

29 January 2008

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16 September 2017

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16 September 2017

volume

16

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16 September 2017

issue

3

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16 September 2017

page(s)

599-606

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Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer

16 September 2017

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1 reference

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Effects of the tumor vasculature targeting agent NGR-TNF on the tumor microenvironment in murine lymphomas

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Vascular patterns in reactive lymphoid tissue and in non-Hodgkin's lymphoma

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The VHL/HIF oxygen-sensing pathway and its relevance to kidney disease

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Interactions between hypoxia and epidermal growth factor receptor in non-small-cell lung cancer

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Hypoxia-inducible factor-1alpha expression requires PI 3-kinase activity and correlates with Akt1 phosphorylation in invasive breast carcinomas

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7 January 2021

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7 January 2021

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

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7 January 2021

Hypoxia in head and neck cancer

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7 January 2021

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

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Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1.

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Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells

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7 January 2021

Culturing at atmospheric oxygen levels impacts lymphocyte function

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7 January 2021

Hypoxia regulates expression and activity of Kv1.3 channels in T lymphocytes: a possible role in T cell proliferation.

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7 January 2021

Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions

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7 January 2021

Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors

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7 January 2021

Hypoxia inducible factor 1 alpha regulates T cell receptor signal transduction.

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7 January 2021

Effects of hypoxia on interleukin-2 mRNA expression by T lymphocytes

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7 January 2021

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

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7 January 2021

The regulated expression of erythropoietin by two human hepatoma cell lines

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7 January 2021

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

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7 January 2021

Hypoxia-inducible factor 1: master regulator of O2 homeostasis

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7 January 2021

Generation of bidirectional hypoxia/HIF-responsive expression vectors to target gene expression to hypoxic cells

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7 January 2021

Administration of neomycin resistance gene marked EBV specific cytotoxic T-lymphocytes to patients with relapsed EBV-positive Hodgkin disease.

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An inducible caspase 9 safety switch for T-cell therapy

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Induction of therapeutic T-cell responses to subdominant tumor-associated viral oncogene after immunization with replication-incompetent polyepitope adenovirus vaccine

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7 January 2021

Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents

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7 January 2021

Hypoxia-inducible factor regulates survival of antigen receptor-driven T cells

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7 January 2021

Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis

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7 January 2021

TCR engagement increases hypoxia-inducible factor-1 alpha protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells

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7 January 2021

Energy metabolism and T-cell-mediated cytolysis. I. Synergism between inhibitors of respiration and glycolysis

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7 January 2021

Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1 alpha in activated T lymphocytes

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7 January 2021

IL-15 and IL-2: a matter of life and death for T cells in vivo

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7 January 2021

Cancer regression in patients after transfer of genetically engineered lymphocytes

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7 January 2021

Lentivirus Vectors Encoding Both Central Polypurine Tract and Posttranscriptional Regulatory Element Provide Enhanced Transduction and Transgene Expression

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7 January 2021

Synergy between tumor immunotherapy and antiangiogenic therapy

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7 January 2021

Targeted elimination of prostate cancer by genetically directed human T lymphocytes

1 reference

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7 January 2021

IFN- -Inducible T Cell Chemoattractant Is a Potent Stimulator of Normal Human Blood T Lymphocyte Transendothelial Migration: Differential Regulation by IFN- and TNF-

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300391

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16 September 2017

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