(Q39573956)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418741%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Simultaneous targeting of P-gp and XIAP with siRNAs increases sensitivity of P-gp overexpressing CML cells to imatinib (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418741%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

2

1 reference

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26 January 2020

Hugo Seca

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418741%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Guimaraes JE

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418741%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

M Helena Vasconcelos

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418741%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

publication date

1 March 2011

1 reference

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26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418741%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418741%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418741%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

100-108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418741%20AND%20SRC:MED&resulttype=core&format=json

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

26 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

BCR-ABL activates pathways mediating cytokine independence and protection against apoptosis in murine hematopoietic cells in a dose-dependent manner

21 January 2018

1 reference

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Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

P-glycoprotein-mediated drug efflux is a resistance mechanism of chronic myelogenous leukemia cells to treatment with imatinib mesylate

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Apoptosis: a link between cancer genetics and chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Death receptors in chemotherapy and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

IAP family protein expression correlates with poor outcome of multiple myeloma patients in association with chemotherapy-induced overexpression of multidrug resistance genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Specific downregulation of bcl-2 and xIAP by RNAi enhances the effects of chemotherapeutic agents in MCF-7 human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Chemosensitization effects of XIAP downregulation in K562 leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Limited synergistic effect of antisense oligonucleotides against bcr-abl and transferrin receptor mRNA in leukemic cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

IAP-targeted therapies for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a breakthrough in anticancer therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

P-glycoprotein activity and biological response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Resistance to diverse apoptotic triggers in multidrug resistant HL60 cells and its possible relationship to the expression of P-glycoprotein, Fas and of the novel anti-apoptosis factors IAP (inhibitory of apoptosis proteins).

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

siRNA-based targeting of antiapoptotic genes can reverse chemoresistance in P-glycoprotein expressing chondrosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Simultaneous modulation of multidrug resistance and antiapoptotic cellular defense by MDR1 and BCL-2 targeted antisense oligonucleotides enhances the anticancer efficacy of doxorubicin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Killing the messenger: short RNAs that silence gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

Multidrug reverting activity toward leukemia cells in a group of new verapamil analogues with low cardiovascular activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F102453311X12940641877803

10.1179/102453311X12940641877803

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418741%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference