(Q39580327)

13 September 2017

PTEN deletion and heme oxygenase-1 overexpression cooperate in prostate cancer progression and are associated with adverse clinical outcome (English)

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13 September 2017

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Jeremy A Squire

9

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author name string

Yunru Li

1

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13 September 2017

Jie Su

2

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13 September 2017

Xiao DingZhang

3

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13 September 2017

Jianguo Zhang

4

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13 September 2017

Maisa Yoshimoto

5

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13 September 2017

Shuhong Liu

6

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13 September 2017

Krikor Bijian

7

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13 September 2017

Ajay Gupta

8

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13 September 2017

Moulay A Alaoui Jamali

10

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13 September 2017

Tarek A Bismar

11

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13 September 2017

7 March 2011

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13 September 2017

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13 September 2017

224

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13 September 2017

1

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13 September 2017

90-100

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The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase

13 September 2017

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The heme oxygenase system: a regulator of second messenger gases

21 January 2018

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The antiapoptotic effect of heme oxygenase-1 in endothelial cells involves the degradation of p38 alpha MAPK isoform.

21 January 2018

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Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite

21 January 2018

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Growth factors and heme oxygenase-1: perspectives in physiology and pathophysiology

21 January 2018

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Heme oxygenase-1 in tumors: is it a false friend?

21 January 2018

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Heme oxygenase-1 accelerates tumor angiogenesis of human pancreatic cancer

21 January 2018

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Expression of heme oxygenase-1 (HSP32) in human prostate: normal, hyperplastic, and tumor tissue distribution

21 January 2018

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A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer

21 January 2018

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Critical role of endogenous heme oxygenase 1 as a tuner of the invasive potential of prostate cancer cells

21 January 2018

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Nuclear translocation of haeme oxygenase-1 is associated to prostate cancer

21 January 2018

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PTEN and the PI3-kinase pathway in cancer

21 January 2018

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New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

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Human cancer, PTEN and the PI-3 kinase pathway

21 January 2018

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Interphase FISH analysis of PTEN in histologic sections shows genomic deletions in 68% of primary prostate cancer and 23% of high-grade prostatic intra-epithelial neoplasias

21 January 2018

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Mutation and expression analysis of the putative prostate tumour-suppressor gene PTEN

21 January 2018

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Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

21 January 2018

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Pten inactivation and the emergence of androgen-independent prostate cancer.

21 January 2018

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Ferulic acid protects human umbilical vein endothelial cells from radiation induced oxidative stress by phosphatidylinositol 3-kinase and extracellular signal-regulated kinase pathways

21 January 2018

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Quercetin-3-O-beta-d-glucuronopyranoside (QGC)-induced HO-1 expression through ERK and PI3K activation in cultured feline esophageal epithelial cells

21 January 2018

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The anti-inflammatory role of heme oxygenase-1 in lipopolysaccharide and cytokine-stimulated inducible nitric oxide synthase and nitric oxide production in human periodontal ligament cells

21 January 2018

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PTEN genomic deletion is an early event associated with ERG gene rearrangements in prostate cancer

21 January 2018

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Fascin regulates prostate cancer cell invasion and is associated with metastasis and biochemical failure in prostate cancer

21 January 2018

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FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion

21 January 2018

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Overexpression of SERTAD3, a putative oncogene located within the 19q13 amplicon, induces E2F activity and promotes tumor growth

21 January 2018

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Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness

21 January 2018

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Convergence of hormones, inflammation, and energy-related factors: a novel pathway of cancer etiology

21 January 2018

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A new role for PTEN in regulating transient receptor potential canonical channel 6-mediated Ca2+ entry, endothelial permeability, and angiogenesis

21 January 2018

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Carbon monoxide promotes VEGF expression by increasing HIF-1alpha protein level via two distinct mechanisms, translational activation and stabilization of HIF-1alpha protein

21 January 2018

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Heme oxygenase-1 and carbon monoxide promote neovascularization after myocardial infarction by modulating the expression of HIF-1alpha, SDF-1alpha and VEGF-B.

21 January 2018

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Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis

21 January 2018

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Fos cooperation with PTEN loss elicits keratoacanthoma not carcinoma, owing to p53/p21 WAF-induced differentiation triggered by GSK3beta inactivation and reduced AKT activity

21 January 2018

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Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.

21 January 2018

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Cooperation between FGF8b overexpression and PTEN deficiency in prostate tumorigenesis

21 January 2018

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PTEN deficiency in a luminal ErbB-2 mouse model results in dramatic acceleration of mammary tumorigenesis and metastasis

21 January 2018

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Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis

21 January 2018

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Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

21 January 2018

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Carbon monoxide donors or heme oxygenase-1 (HO-1) overexpression blocks interleukin-18-mediated NF-kappaB-PTEN-dependent human cardiac endothelial cell death

21 January 2018

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Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals

21 January 2018

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PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer.

21 January 2018

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Restoration of PTEN expression alters the sensitivity of prostate cancer cells to EGFR inhibitors

21 January 2018

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Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation.

21 January 2018

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Independent and cooperative roles of tumor necrosis factor-alpha, nuclear factor-kappaB, and bone morphogenetic protein-2 in regulation of metastasis and osteomimicry of prostate cancer cells and differentiation and mineralization of MC3T3-E1 osteob

21 January 2018

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Antimetastatic potential of fisetin involves inactivation of the PI3K/Akt and JNK signaling pathways with downregulation of MMP-2/9 expressions in prostate cancer PC-3 cells

21 January 2018

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Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway

21 January 2018

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PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches

21 January 2018

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The PTEN/Akt pathway dictates the direct alphaVbeta3-dependent growth-inhibitory action of an active fragment of tumstatin in glioma cells in vitro and in vivo.

21 January 2018

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Nerve growth factor induces endothelial cell invasion and cord formation by promoting matrix metalloproteinase-2 expression through the phosphatidylinositol 3-kinase/Akt signaling pathway and AP-2 transcription factor.

21 January 2018

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Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling

21 January 2018

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Regulation of androgen receptor signaling by PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor through distinct mechanisms in prostate cancer cells

21 January 2018

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Conditional expression of PTEN alters the androgen responsiveness of prostate cancer cells

21 January 2018

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Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress

21 January 2018

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Homeostatic response under carcinogen withdrawal, heme oxygenase 1 expression and cell cycle association

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.2855

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release_ato7532c7rhrdc32z4ilo4r4nq

13 September 2017

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