(Q39645153)

13 September 2017

title

Serine residues in the LAT adaptor are essential for TCR-dependent signal transduction (English)

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13 September 2017

10

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Margarita Domínguez-Villar

13 September 2017

Rut Valdor

6

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Margarita Domínguez-Villar

5

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Francisco Garcia-Cozar

Francisco García-Cózar

8

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Enrique Aguado

Enrique Aguado

11

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José Yélamos

José Yélamos

3

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Antonio García-Blesa

2

Antonio García-Blesa

1 reference

13 September 2017

Mario Martínez-Florensa

1

Mario Martínez-Florensa

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13 September 2017

Alba Muñoz-Suano

4

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13 September 2017

Antonio Alonso

7

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13 September 2017

Pedro Aparicio

9

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13 September 2017

publication date

12 October 2010

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Journal of Leukocyte Biology

13 September 2017

published in

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13 September 2017

volume

89

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13 September 2017

issue

1

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13 September 2017

page(s)

63-73

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Regulation of hematopoietic cell development and activation by adapter proteins

13 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Appearance of the LAT protein at an early stage of B-cell development and its possible role

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Grf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LAT

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

LAT regulates gammadelta T cell homeostasis and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Essential role of LAT in T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Identification of the minimal tyrosine residues required for linker for activation of T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Induction of T helper type 2 immunity by a point mutation in the LAT adaptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

A LAT mutation that inhibits T cell development yet induces lymphoproliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Negative feedback loop in T-cell activation through MAPK-catalyzed threonine phosphorylation of LAT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Sequence and structure-based prediction of eukaryotic protein phosphorylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Casein kinase I: from obscurity to center stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

At least two non-antigen-binding molecules are required for signal transduction by the T-cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Altered calcium regulation in freshly isolated aortic smooth muscle cells from bile duct-ligated rats: role of nitric oxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

The type 1 cysteinyl leukotriene receptor triggers calcium influx and chemotaxis in mouse alpha beta- and gamma delta effector T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Casein kinase II phosphorylation of E-cadherin increases E-cadherin/beta-catenin interaction and strengthens cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Requirement for phospholipase C-gamma1 enzymatic activity in growth factor-induced mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Early phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

A dynamic constitutive and inducible binding of c-Cbl by PLCgamma1 SH3 and SH2 domains (negatively) regulates antigen receptor-induced PLCgamma1 activation in lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Recruitment and activation of PLCgamma1 in T cells: a new insight into old domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

c-Cbl-mediated regulation of LAT-nucleated signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

AICAR suppresses IL-2 expression through inhibition of GSK-3 phosphorylation and NF-AT activation in Jurkat T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Expression of CD45 lacking the catalytic protein tyrosine phosphatase domain modulates Lck phosphorylation and T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Rapid in vivo analysis of mutant forms of the LAT adaptor using Pax5-Lat double-deficient pro-B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Interaction between O-GlcNAc modification and tyrosine phosphorylation of prohibitin: implication for a novel binary switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

The O-linked N-acetylglucosamine modification in cellular signalling and the immune system. 'Protein modifications: beyond the usual suspects' review series

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Role of the LAT adaptor in T-cell development and Th2 differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

Vav1 Transduces T Cell Receptor Signals to the Activation of the Ras/ERK Pathway via LAT, Sos, and RasGRP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0509342

21 January 2018

Identifiers

DOI

10.1189/JLB.0509342

1 reference

13 September 2017

1 reference