(Q39645850)

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From preclinical to human--prediction of oral absorption and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach in an industrial setting: a workflow by using case example

scientific article published on March 2012

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scholarly article

1 reference

Europe PubMed Central

13 September 2017

From preclinical to human--prediction of oral absorption and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach in an industrial setting: a workflow by using case example (English)

1 reference

Europe PubMed Central

13 September 2017

1 reference

based on heuristic

inferred from title

drug interaction

0 references

author name string

Vikash Kumar Sinha

1

1 reference

Europe PubMed Central

13 September 2017

Jan Snoeys

2

1 reference

Europe PubMed Central

13 September 2017

Nancy Van Osselaer

3

1 reference

Europe PubMed Central

13 September 2017

Achiel Van Peer

4

1 reference

Europe PubMed Central

13 September 2017

Claire Mackie

5

1 reference

Europe PubMed Central

13 September 2017

Donald Heald

6

1 reference

Europe PubMed Central

13 September 2017

language of work or name

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based on heuristic

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publication date

1 March 2012

1 reference

Europe PubMed Central

13 September 2017

Biopharmaceutics and Drug Disposition

1 reference

Europe PubMed Central

13 September 2017

33

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Europe PubMed Central

13 September 2017

111-121

1 reference

Europe PubMed Central

13 September 2017

2

1 reference

Europe PubMed Central

13 September 2017

Prediction of intestinal first-pass drug metabolism

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Population-based mechanistic prediction of oral drug absorption

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Physiological parameter values for physiologically based pharmacokinetic models

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Prediction of the volumes of distribution of basic drugs in humans based on data from animals

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Physiologically based pharmacokinetic modeling 1: predicting the tissue distribution of moderate-to-strong bases.

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Physiologically based pharmacokinetic modelling 2: predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions.

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Predicting the impact of physiological and biochemical processes on oral drug bioavailability

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

A compartmental absorption and transit model for estimating oral drug absorption.

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Interplay of metabolism and transport in determining oral drug absorption and gut wall metabolism: a simulation assessment using the "Advanced Dissolution, Absorption, Metabolism (ADAM)" model.

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Implications of mechanism-based inhibition of CYP2D6 for the pharmacokinetics and toxicity of MDMA.

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

The Simcyp population-based ADME simulator

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Cytochrome p450 turnover: regulation of synthesis and degradation, methods for determining rates, and implications for the prediction of drug interactions

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

In vitro cytochrome P450 inhibition data and the prediction of drug-drug interactions: qualitative relationships, quantitative predictions, and the rank-order approach

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

The utility of in vitro cytochrome P450 inhibition data in the prediction of drug-drug interactions

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

First-pass metabolism of midazolam by the human intestine.

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Estimation of effective intestinal membrane permeability considering bile micelle solubilisation

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Utility of a physiologically-based pharmacokinetic (PBPK) modeling approach to quantitatively predict a complex drug-drug-disease interaction scenario for rivaroxaban during the drug review process: implications for clinical practice.

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Evaluation of exposure change of nonrenally eliminated drugs in patients with chronic kidney disease using physiologically based pharmacokinetic modeling and simulation.

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Role of modelling and simulation: a European regulatory perspective.

1 reference

https://api.crossref.org/works/10.1002%2FBDD.1782

21 January 2018

Identifiers

10.1002/BDD.1782

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

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