(Q45901623)

English

Evaluation of exposure change of nonrenally eliminated drugs in patients with chronic kidney disease using physiologically based pharmacokinetic modeling and simulation.

scientific article published in January 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Evaluation of exposure change of nonrenally eliminated drugs in patients with chronic kidney disease using physiologically based pharmacokinetic modeling and simulation. (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

chronic renal insufficiency

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Ping Zhao

1

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Manuela de L T Vieira

2

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Joseph A Grillo

3

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Pengfei Song

4

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Ta-Chen Wu

5

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Jenny H Zheng

6

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Vikram Arya

7

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Eva Gil Berglund

8

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Arthur J Atkinson

9

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Yuichi Sugiyama

10

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

K Sandy Pang

11

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Kellie S Reynolds

12

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Darrell R Abernethy

13

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Lei Zhang

14

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Lawrence J Lesko

15

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Shiew-Mei Huang

16

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

publication date

1 January 2012

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

The Journal of Clinical Pharmacology

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

52

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

1 Suppl

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

91S-108S

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Drug development perspective on pharmacokinetic studies of new drugs in patients with renal impairment.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Altered nonrenal drug clearance in ESRD.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Hepatic drug metabolism and transport in patients with kidney disease.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Pharmacokinetic modeling of the hepatobiliary transport mediated by cooperation of uptake and efflux transporters

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Application of physiologically based pharmacokinetic modeling and clearance concept to drugs showing transporter-mediated distribution and clearance in humans

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https://api.crossref.org/works/10.1177%2F0091270011415528

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Applications of physiologically based pharmacokinetic (PBPK) modeling and simulation during regulatory review

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The effects of age and renal and hepatic impairment on the pharmacokinetics of sildenafil

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Comparative human pharmacokinetics and metabolism of single-dose oral and intravenous sildenafil

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

The effects of steady-state erythromycin and azithromycin on the pharmacokinetics of sildenafil in healthy volunteers.

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Pharmacokinetics of sildenafil after single oral doses in healthy male subjects: absolute bioavailability, food effects and dose proportionality

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Pharmacokinetics of telithromycin: application to dosing in the treatment of community-acquired respiratory tract infections

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Pharmacokinetics and safety of the ketolide telithromycin in patients with renal impairment

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Clinical pharmacokinetics of telithromycin, the first ketolide antibacterial

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry, biology, anatomy, physiology and genetics: A tale of 'bottom-up' vs 'top-down' recogn

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Simulation and prediction of in vivo drug metabolism in human populations from in vitro data

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Physiologically based mechanistic modelling to predict complex drug-drug interactions involving simultaneous competitive and time-dependent enzyme inhibition by parent compound and its metabolite in both liver and gut - the effect of diltiazem on th

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21 January 2018

Tissue distribution of basic drugs: accounting for enantiomeric, compound and regional differences amongst beta-blocking drugs in rat.

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Physiologically based pharmacokinetic modeling 1: predicting the tissue distribution of moderate-to-strong bases.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Physiologically based pharmacokinetic modelling 2: predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Prediction of intestinal first-pass drug metabolism

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

The Simcyp population-based ADME simulator

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Cyclosporine markedly raises the plasma concentrations of repaglinide

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21 January 2018

Effects of gemfibrozil and atorvastatin on the pharmacokinetics of repaglinide in relation to SLCO1B1 polymorphism

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Pharmacokinetics and absolute oral bioavailability of an 800-mg oral dose of telithromycin in healthy young and elderly volunteers

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Emerging evidence of the impact of kidney disease on drug metabolism and transport

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Development of a physiology-based whole-body population model for assessing the influence of individual variability on the pharmacokinetics of drugs.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Physiologically-Based Pharmacokinetics in Drug Development and Regulatory Science

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21 January 2018

Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children

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https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

A semi-mechanistic model to predict the effects of liver cirrhosis on drug clearance

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21 January 2018

Physiology-based simulations of a pathological condition: prediction of pharmacokinetics in patients with liver cirrhosis

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21 January 2018

Development and evaluation of a generic physiologically based pharmacokinetic model for children.

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21 January 2018

Identifiers

10.1177/0091270011415528

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

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