(Q51917380)

English

Development of a physiology-based whole-body population model for assessing the influence of individual variability on the pharmacokinetics of drugs.

scientific article published on 13 March 2007

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17431751%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Development of a physiology-based whole-body population model for assessing the influence of individual variability on the pharmacokinetics of drugs (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17431751%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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pharmacokinetics

1 reference

based on heuristic

inferred from title

8

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29 December 2019

7

1 reference

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29 December 2019

author name string

Stefan Willmann

1

1 reference

Europe PubMed Central

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29 December 2019

Karsten Höhn

2

1 reference

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29 December 2019

Andrea Edginton

3

1 reference

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29 December 2019

Michael Sevestre

4

1 reference

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29 December 2019

Juri Solodenko

5

1 reference

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29 December 2019

Wolfgang Weiss

6

1 reference

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29 December 2019

publication date

13 March 2007

1 reference

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29 December 2019

Journal of Pharmacokinetics and Pharmacodynamics

1 reference

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29 December 2019

34

1 reference

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29 December 2019

401-431

1 reference

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29 December 2019

3

1 reference

Europe PubMed Central

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29 December 2019

https://scigraph.springernature.com/pub.10.1007/s10928-007-9053-5

0 references

CLINICAL CALORIMETRY

1 reference

https://api.crossref.org/works/10.1007%2FS10928-007-9053-5

21 January 2018

Effect of body size, ponderosity, and blood pressure on left ventricular growth in children and young adults in the Bogalusa Heart Study

1 reference

https://api.crossref.org/works/10.1007%2FS10928-007-9053-5

21 January 2018

Leukocytosis: basics of clinical assessment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

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Diazepam pharamacokinetics from preclinical to phase I using a Bayesian population physiologically based pharmacokinetic model with informative prior distributions in WinBUGS.

1 reference

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12 December 2020

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Development and evaluation of a generic physiologically based pharmacokinetic model for children.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

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A formula to estimate the approximate surface area if height and weight be known. 1916.

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A population pharmacokinetic model for paclitaxel in the presence of a novel P-gp modulator, Zosuquidar Trihydrochloride (LY335979)

1 reference

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12 December 2020

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Human variability in the renal elimination of foreign compounds and renal excretion-related uncertainty factors for risk assessment

1 reference

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12 December 2020

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Incorporating pharmacokinetic differences between children and adults in assessing children's risks to environmental toxicants

1 reference

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12 December 2020

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A physiological model for the estimation of the fraction dose absorbed in humans.

1 reference

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12 December 2020

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Pharmacokinetics in older persons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

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Geometric method for measuring body surface area: a height-weight formula validated in infants, children, and adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

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Stochastic response surface methods (SRSMs) for uncertainty propagation: application to environmental and biological systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simplified calculation of body-surface area.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of paclitaxel administered as a 3-hour or 96-hour infusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

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Measurement of adipose tissue blood flow and perfusion in man by uptake of 85Kr

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The associations of body size and body composition with left ventricular mass: impacts for indexation in adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Population pharmacokinetics I: background, concepts, and models

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new method for indexing left ventricular mass for differences in body size.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predictability of the effects of race or ethnicity on pharmacokinetics of drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development and validation of a method to determine the unbound paclitaxel fraction in human plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modeling interindividual variation in physiological factors used in PBPK models of humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

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Proposed occupational exposure limits for select ethylene glycol ethers using PBPK models and Monte Carlo simulations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A priori prediction of tissue:plasma partition coefficients of drugs to facilitate the use of physiologically-based pharmacokinetic models in drug discovery.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

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Ciprofloxacin greatly increases concentrations and hypotensive effect of tizanidine by inhibiting its cytochrome P450 1A2-mediated presystemic metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

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The development of a stochastic physiologically-based pharmacokinetic model for lead

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

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Assessing the reliability of PBPK models using data from methyl chloride-exposed, non-conjugating human subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimation of human body surface area from height and weight

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Utility of physiologically based pharmacokinetic models to drug development and rational drug discovery candidate selection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paclitaxel metabolism in rat and human liver microsomes is inhibited by phenolic antioxidants.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

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Limits of body mass index to detect obesity and predict body composition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

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Autopsy standards of body parameters and fresh organ weights in nonmacerated and macerated human fetuses

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

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Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: theophylline and midazolam as model drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

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Organ weight in 684 adult autopsies: new tables for a Caucasoid population.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

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A review of the microcirculation of adipose tissue: anatomic, metabolic, and angiogenic perspectives

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Sonographic estimation of fetal liver weight: an additional biometric parameter for assessment of fetal growth.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiologically based modeling of the inhalation kinetics of styrene in humans using a bayesian population approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcutaneous adipose tissue blood flow in the abdominal and femoral regions in obese women: effect of fasting

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of physiologically based pharmacokinetic modeling to investigate individual versus population risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of solvent central nervous system toxicity and ethanol interactions using a human population physiologically based kinetic and dynamic model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

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Early determinants of childhood overweight and adiposity in a birth cohort study: role of breast-feeding

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

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Uncertainty factors for chemical risk assessment. human variability in the pharmacokinetics of CYP1A2 probe substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

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Effects of obesity on pharmacokinetics implications for drug therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

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Cadaver studies and their impact on the understanding of human adiposity

1 reference

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12 December 2020

based on heuristic

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From physicochemistry to absorption and distribution: predictive mechanistic modelling and computational tools

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incorporating Monte Carlo simulation into physiologically based pharmacokinetic models using advanced continuous simulation language (ACSL): a computational method.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastrointestinal secretion of ciprofloxacin. Evaluation of the charcoal model for investigations in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bayesian estimation of variability in adipose tissue blood flow in man by physiologically based pharmacokinetic modeling of inhalation exposure to toluene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

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Human variability in CYP3A4 metabolism and CYP3A4-related uncertainty factors for risk assessment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

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Generalized abdominal visceral fat prediction models for black and white adults aged 17-65 y: the HERITAGE Family Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ontogeny of hepatic and renal systemic clearance pathways in infants: part I.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of intravenous ciprofloxacin in normal and renally impaired subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiology-based pharmacokinetic modeling: ready to be used

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

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Ultrasound, spleen and portal hypertension.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17431751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10928-007-9053-5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17431751%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17431751%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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