(Q44247783)

1 December 2017

title

Human variability in CYP3A4 metabolism and CYP3A4-related uncertainty factors for risk assessment (English)

1 reference

1 December 2017

Dorne JL

1

1 reference

1 December 2017

Walton K

series ordinal

2

1 reference

1 December 2017

Renwick AG

series ordinal

3

1 reference

1 December 2017

language of work or name

1 reference

1 February 2003

1 reference

Food and Chemical Toxicology

1 December 2017

published in

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1 December 2017

volume

41

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1 December 2017

issue

2

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1 December 2017

page(s)

201-224

1 reference

Lidocaine disposition in obesity.

1 December 2017

cites work

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7 January 2021

Ethnic differences in the pharmacokinetics of oral nifedipine

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The influence of dose and ethnic origins on the pharmacokinetics of nifedipine

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7 January 2021

Effect of route of administration of fluconazole on the interaction between fluconazole and midazolam.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Intersubject and dose-related variability after intravenous administration of erythromycin.

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https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Midazolam kinetics in women of two age groups

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

A pharmacokinetic interaction between roxithromycin and midazolam.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Lack of correlation between in vitro and in vivo studies on the effects of tangeretin and tangerine juice on midazolam hydroxylation.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effect of grapefruit juice and naringin on nisoldipine pharmacokinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

A comparative assessment of amlodipine and felodipine ER: pharmacokinetic and pharmacodynamic indices

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

A comparison of the pharmacokinetics of nisoldipine in elderly and young subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Population distribution and effects on drug metabolism of a genetic variant in the 5' promoter region of CYP3A4

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Acute antihypertensive effect and pharmacokinetics of a tablet preparation of nifedipine

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Lidocaine metabolism in human liver microsomes by cytochrome P450IIIA4.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Inhibition of alfentanil metabolism by erythromycin.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Influence of long-term infusions on lidocaine kinetics.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Bioavailability of diltiazem as a function of the administered dose

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics and bioavailability of a sustained-release diltiazem formulation (Mono-Tildiem LP 300 mg) after repeated administration in healthy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The pharmacokinetics of extended release felodipine in children

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Metronidazole Impairs Clearance of Phenytoin but Not of Alprazolam or Lorazepam

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Dose dependent pharmacokinetics of midazolam.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The pharmacokinetics and pharmacodynamics of diltiazem and its metabolites in healthy adults after a single oral dose

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The Pharmacokinetics of Alfentanil (R39209): A New Opioid Analgesic

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Comparative pharmacokinetics of fentanyl and alfentanil.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Disposition of alfentanil in patients receiving a renal transplant.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of felodipine in chronic hemodialysis patients

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Diltiazem pharmacokinetics in elderly volunteers after single and multiple doses

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Multiple Dose Pharmacokinetics of Four Different Doses of Nisoldipine in Hypertensive Patients

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Single-dose and steady-state pharmacokinetics of diltiazem administered in two different tablet formulations

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The influence of infusion rate on the hemodynamic effects of felodipine

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics and metabolism of lidocaine in patients with renal failure

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Onset of xenobiotic metabolism in children: toxicological implications

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Age-dependent lidocaine disposition in patients with acute myocardial infarction.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Rectal pharmacokinetics of budesonide

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The effect of age and liver disease on the pharmacokinetics of the calcium antagonist, nisoldipine

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Therapeutic drug monitoring of alprazolam in adolescents with asthma.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Cytochrome P450 3A: ontogeny and drug disposition

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Alfentanil in infants and children with congenital heart defects

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics and Pharmacodynamics of Triazolam After Two Intermittent Doses in Obese and Normal-Weight Men

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Uncertainty factors for chemical risk assessment. human variability in the pharmacokinetics of CYP1A2 probe substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Human variability in glucuronidation in relation to uncertainty factors for risk assessment

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate?

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Plasma levels, protein binding, and elimination data of lidocaine and active metabolites in cardiac patients of various ages

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of felodipine after intravenous and chronic oral administration in patients with congestive heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Analysis of zolpidem in human plasma by high-performance liquid chromatography with fluorescence detection: application to single-dose pharmacokinetic studies

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Triazolam disposition

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Absorption, distribution and elimination of felodipine in man

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Felodipine kinetics in healthy men.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of felodipine in patients with impaired renal function

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Identification and functional characterization of eight CYP3A4 protein variants

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of nifedipine after oral administration in chronic liver disease

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Cimetidine and ranitidine increase midazolam bioavailability.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics and pharmacodynamics of zolpidem following repeated doses in hemodialyzed uraemic patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics and pharmacodynamics of alprazolam following single and multiple oral doses of a sustained-release formulation

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of the infusion of alfentanil in man.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Comparative pharmacokinetics of alprazolam and lorazepam in humans and in African Green Monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effect of carbamazepine on the single oral dose pharmacokinetics of alprazolam

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Racial background and lidocaine pharmacokinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The pharmacokinetics of alfentanil in children.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Biotransformation of alprazolam by members of the human cytochrome P4503A subfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Comparative single-dose kinetics and dynamics of lorazepam, alprazolam, prazepam, and placebo

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Kinetic and dynamic interaction study of zolpidem with ketoconazole, itraconazole, and fluconazole

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Fluoxetine impairs clearance of alprazolam but not of clonazepam

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Ketoconazole inhibition of triazolam and alprazolam clearance: differential kinetic and dynamic consequences

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Influence of grapefruit juice on cisapride pharmacokinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Oxidation of dihydropyridine calcium channel blockers and analogues by human liver cytochrome P-450 IIIA4.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effect of food on the pharmacokinetics of cyclosporine in healthy subjects following oral and intravenous administration

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of erythromycin in normal and alcoholic liver disease subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effect of indomethacin on the pharmacokinetics and pharmacodynamics of felodipine

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

I.v. fentanyl decreases the clearance of midazolam.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Risk evaluation: criteria arising from legal traditions and experience with quantitative risk assessment in the United States

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Comparative bioavailability of a cisapride suppository and tablet formulation in healthy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Alfentanil kinetics in the elderly

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics and bioavailability of midazolam in man

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

RO 48-6791--a short acting benzodiazepine. Pharmacokinetics and pharmacodynamics in young and old subjects in comparison to midazolam

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of diltiazem after intravenous and oral administration

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of nifedipine slow release tablet in Mexican subjects: further evidence for an oxidation polymorphism

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Alfentanil pharmacokinetics in patients undergoing abdominal aortic surgery.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effect of age and gender on the activity of human hepatic CYP3A

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effect of erythromycin and itraconazole on the pharmacokinetics of intravenous lignocaine.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effect of erythromycin and itraconazole on the pharmacokinetics of oral lignocaine.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of midazolam in critically ill neonates.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Predictability of the effects of race or ethnicity on pharmacokinetics of drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Alprazolam Pharmacokinetics in Alcoholic Liver Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of oral triazolam in children

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Quantification of 3-month intraindividual variability and the influence of sex and menstrual cycle phase on CYP3A activity as measured by phenotyping with intravenous midazolam.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Assessment of cytochrome P450 3A4 activity during the menstrual cycle using alfentanil as a noninvasive probe.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The role of cytochrome P450 3A4 in alfentanil clearance. Implications for interindividual variability in disposition and perioperative drug interactions.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Triazolam pharmacokinetics and pharmacodynamics in Caucasians and Southern Asians: ethnicity and CYP3A activity

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Repeated consumption of grapefruit juice considerably increases plasma concentrations of cisapride

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Variability in nifedipine pharmacokinetics and dynamics: a new oxidation polymorphism in man

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Nifedipine: kinetics and hemodynamic effects in patients with liver cirrhosis after intravenous and oral administration

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Physiologic and temporal variation in hepatic elimination of midazolam.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The influence of dosage time of midazolam on its pharmacokinetics and effects in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Enhanced effect of triazolam with diltiazem

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Metabolism of cytochrome P4503A substrates in vivo administered by the same route: lack of correlation between alfentanil clearance and erythromycin breath test.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Triazolam Pharmacokinetics After Intravenous, Oral, and Sublingual Administration

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Alprazolam in the elderly: pharmacokinetics and pharmacodynamics during multiple dosing

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effects of end stage renal disease and aluminium hydroxide on triazolam pharmacokinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Interaction between grapefruit juice and midazolam in humans*

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics and blood pressure effects of felodipine in elderly hypertensive patients. A comparison with young healthy subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Acute and steady-state pharmacokinetics and antihypertensive effects of felodipine in patients with normal and impaired renal function

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Cyclosporin: pharmacokinetics and detailed studies of plasma and erythrocyte binding during intravenous and oral administration.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetic and pharmacodynamic interactions between nisoldipine and propranolol.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Comparison of alprazolam plasma levels in normal Asian and Caucasian male volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Demographic factors influencing cyclosporine pharmacokinetic parameters in patients with uremia: racial differences in bioavailability

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The erythromycin breath test predicts the clearance of midazolam.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics and pharmacodynamics of intravenous midazolam in patients with severe alcoholic cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Haemodialysis does not affect the pharmacokinetics of nifedipine

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Comparative bioavailability of two immediate release tablets of cisapride in healthy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Concurrent administration of the erythromycin breath test (EBT) and oral midazolam as in vivo probes for CYP3A activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

A comparison of alfentanil pharmacokinetics in children and adults.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Propofol alters the pharmacokinetics of alfentanil in healthy male volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of lignocaine in children after infiltration for cleft palate surgery

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Calcium antagonists in geriatric patients: diltiazem in elderly persons with hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Simultaneous modeling of the pharmacokinetics and pharmacodynamics of midazolam and diazepam

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Dose-independent pharmacokinetics of intravenous lidocaine in humans.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Lack of influence of cigarette smoking on triazolam pharmacokinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

On the intraindividual variability and chronobiology of cyclosporine pharmacokinetics in renal transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Bioavailability of terfenadine in man

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Relationship between single oral dose pharmacokinetics of alprazolam and triazolam

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration method

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effect of an oral contraceptive preparation containing ethinylestradiol and gestodene on CYP3A4 activity as measured by midazolam 1'-hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The pharmacodynamics and pharmacokinetics of a new calcium antagonist nisoldipine in normotensive and hypertensive subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of budesonide in children with asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of midazolam following intravenous and oral administration in patients with chronic liver disease and in healthy subjects.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of alfentanil in total i.v. anaesthesia.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics and the pharmacodynamic action of midazolam in young and elderly patients undergoing tooth extraction.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of midazolam and alfentanil in outpatient general anesthesia. A study with concomitant thiopentone, flumazenil or placebo administration

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Factors affecting the absolute bioavailability of nifedipine

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of felodipine in patients with liver disease

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The pharmacokinetics of alfentanil in gynecologic surgical patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Data-derived safety factors for the evaluation of food additives and environmental contaminants

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The influence of posture on the pharmacokinetics of orally administered nifedipine

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Human variability and noncancer risk assessment- An analysis of the default uncertainty factor

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The pharmacokinetics of oral nifedipine--a population study

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

An analysis of the need for an additional uncertainty factor for infants and children

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of midazolam in children: comparative study of intranasal and intravenous administration

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Triazolam in cirrhosis: pharmacokinetics and pharmacodynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of alfentanil in children undergoing surgery.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Kinetics of the epimeric glucocorticoid budesonide

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Evidence for the activation of organophosphate pesticides by cytochromes P450 3A4 and 2D6 in human liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: evidence for an allelic variant with altered catalytic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Alprazolam pharmacokinetics in women on low-dose oral contraceptives

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Lack of bimodality in nifedipine plasma kinetics in a large population of healthy subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Differential effects of quinidine on the disposition of nifedipine, sparteine, and mephenytoin in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Alprazolam in end-stage renal disease: I. Pharmacokinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Midazolam pharmacokinetics following intravenous and buccal administration

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Responses to intravenous and oral diltiazem in elderly and younger patients with systemic hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Midazolam and flumazenil pharmacokinetics and pharmacodynamics following simultaneous administration to human volunteers.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Study of the drug-drug interaction between simvastatin and cisapride in man.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Comparison of the disposition kinetics of lidocaine and (+/-)prilocaine in 20 patients undergoing intravenous regional anaesthesia during day case surgery.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Aging and alfentanil disposition in healthy volunteers and surgical patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

CSF penetration and pharmacokinetics of midazolam.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The pharmacokinetics of midazolam in man.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of midazolam in the aged.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Influence of dosing regimen on alprazolam and metabolite serum concentrations and tolerance to sedative and psychomotor effects

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetic interactions between felodipine and metoprolol

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Stereoselective pharmacokinetics of oral felodipine and nitrendipine in healthy subjects: correlation with nifedipine pharmacokinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

CYP3A activity in European American and Japanese men using midazolam as an in vivo probe

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of intravenous diltiazem and five of its metabolites in patients with chronic renal failure and in healthy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of oral diltiazem and five of its metabolites in patients with chronic renal failure

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Lung deposition of budesonide from a pressurized metered-dose inhaler attached to a spacer

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Evidence of impaired cisapride metabolism in neonates

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of midazolam in anaesthetized cirrhotic patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: effect of ketoconazole.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The pharmacokinetic and pharmacodynamic interaction between propafenone and lidocaine.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effects of a sauna on the pharmacokinetics and pharmacodynamics of midazolam and ephedrine in healthy young women.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effects of heat exposure in a Finnish sauna on the pharmacokinetics and metabolism of midazolam.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics of alfentanil during and after a fixed rate infusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Total and free steady-state plasma levels and pharmacokinetics of nifedipine in patients with terminal renal failure

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The contribution of nisoldipine-induced changes in liver blood flow to its pharmacokinetics after oral administration

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Single- and multiple-dose nisoldipine kinetics and effects in the young, the middle-aged, and the elderly.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Influence of renal function on the pharmacokinetics and cardiovascular effects of nisoldipine after single and multiple dosing

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics and hemodynamic effects of nisoldipine and its interaction with cimetidine

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Nisoldipine: kinetics and effects on blood pressure and heart rate in patients with liver cirrhosis after intravenous and oral administration

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

The pharmacokinetics of midazolam in chronic renal failure patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Alfentanil kinetics in renal insufficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Uncertainty factors for chemical risk assessment: interspecies differences in the in vivo pharmacokinetics and metabolism of human CYP1A2 substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Uncertainty factors for chemical risk assessment: interspecies differences in glucuronidation

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effects of metronidazole on midazolam metabolism in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Urinary metabolites of felodipine, a new vasodilator drug, in man, dog, rat and mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

A comparison of the early pharmacokinetics of midazolam in pregnant and nonpregnant women.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Lack of multiple dosing effect of sertindole on the pharmacokinetics of alprazolam in healthy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetics and psychomotor performance of alprazolam: concentration-effect relationship

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effects of roxithromycin, erythromycin and troleandomycin on their N-demethylation by rat and human cytochrome P450 enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Single-dose pharmacokinetics and pharmacodynamics of oral triazolam in relation to cytochrome P4502C19 (CYP2C19) activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Effect of itraconazole on the single oral dose pharmacokinetics and pharmacodynamics of alprazolam

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Pharmacokinetic profile of cisapride 20 mg after once- and twice-daily dosing.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

Lidocaine kinetics predicted by indocyanine green clearance

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2802%2900209-0

7 January 2021

10.1016/S0278-6915(02)00209-0

Identifiers

DOI

1 reference

1 December 2017

1 reference