(Q39653324)

13 September 2017

title

KIT receptor activation by autocrine and paracrine stem cell factor stimulates growth of merkel cell carcinoma in vitro (English)

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13 September 2017

main subject

Merkel cell carcinoma

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based on heuristic

inferred from title

author

Nektarios Tavernarakis

8

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Efstathios N Stathopoulos

13 September 2017

6

object named as

Efstathios N Stathopoulos

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13 September 2017

author name string

Konstantin Krasagakis

1

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13 September 2017

Irene Fragiadaki

2

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13 September 2017

Maria Metaxari

3

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13 September 2017

Sabine Krüger-Krasagakis

4

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13 September 2017

George N Tzanakakis

5

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13 September 2017

Jürgen Eberle

7

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13 September 2017

Androniki D Tosca

9

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13 September 2017

publication date

1 April 2011

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Journal of Cellular Physiology

13 September 2017

published in

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13 September 2017

volume

226

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13 September 2017

issue

4

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13 September 2017

page(s)

1099-1109

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The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136

13 September 2017

cites work

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Expression of VEGF-A/C, VEGF-R2, PDGF-alpha/beta, c-kit, EGFR, Her-2/Neu, Mcl-1 and Bmi-1 in Merkel cell carcinoma

21 January 2018

1 reference

Clonal integration of a polyomavirus in human Merkel cell carcinoma

21 January 2018

1 reference

PKC412 inhibits in vitro growth of neoplastic human mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107, imatinib, and cladribine (2CdA) and evaluation of cooperative drug effects

21 January 2018

1 reference

Production of a monoclonal antibody that recognizes bovine stem cell factor (SCF) and its use in the detection and quantitation of native soluble bovine SCF in fetal bovine serum.

21 January 2018

1 reference

Expression of stem cell factor (SCF), a KIT ligand, in gastrointestinal stromal tumors (GISTs): a potential marker for tumor proliferation

21 January 2018

1 reference

Neuroendocrine (Merkel cell) carcinoma of the skin. Its natural history, diagnosis, and treatment

21 January 2018

1 reference

The role of KIT in the management of patients with gastrointestinal stromal tumors

21 January 2018

1 reference

Absence of classical MAP kinase pathway signalling in Merkel cell carcinoma

21 January 2018

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Activation of the MAP kinase pathway induces apoptosis in the Merkel cell carcinoma cell line UISO.

21 January 2018

1 reference

Abnormality of c-kit oncoprotein in certain patients with chronic myelogenous leukemia--potential clinical significance

21 January 2018

1 reference

Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage

21 January 2018

1 reference

Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL

21 January 2018

1 reference

Growth and characterization of a cell line from a human primary neuroendocrine carcinoma of the skin (Merkel cell carcinoma) in culture and as xenograft

21 January 2018

1 reference

Interferon-alpha inhibits proliferation and induces apoptosis of merkel cell carcinoma in vitro

21 January 2018

1 reference

Expression of interleukin 10 in human melanoma.

21 January 2018

1 reference

Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study

21 January 2018

1 reference

Altered metabolism of mast-cell growth factor (c-kit ligand) in cutaneous mastocytosis

21 January 2018

1 reference

KIT (CD117): a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation

21 January 2018

1 reference

Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase

21 January 2018

1 reference

Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder

21 January 2018

1 reference

Imatinib mesylate (STI571) inhibits multiple myeloma cell proliferation and potentiates the effect of common antimyeloma agents

21 January 2018

1 reference

Merkel cells and Merkel cell carcinoma express the BCL-2 proto-oncogene

21 January 2018

1 reference

Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

1 reference

Role of the KIT protooncogene in normal and malignant human hematopoiesis

21 January 2018

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Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor

21 January 2018

1 reference

The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins

21 January 2018

1 reference

A comparison of immunohistochemical markers of cell proliferation with experimentally determined growth fraction.

21 January 2018

1 reference

CD117 (KIT receptor) expression in Merkel cell carcinoma

21 January 2018

1 reference

Co expression of SCF and KIT in gastrointestinal stromal tumours (GISTs) suggests an autocrine/paracrine mechanism.

21 January 2018

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Critical roles of c-Kit tyrosine residues 567 and 719 in stem cell factor-induced chemotaxis: contribution of src family kinase and PI3-kinase on calcium mobilization and cell migration

21 January 2018

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Mutation analysis of P73 and TP53 in Merkel cell carcinoma

21 January 2018

1 reference

Effects of AMN107, a novel aminopyrimidine tyrosine kinase inhibitor, on human mast cells bearing wild-type or mutated codon 816 c-kit

21 January 2018

1 reference

Defining protective responses to pathogens: cytokine profiles in leprosy lesions

21 January 2018

1 reference

p14ARF Hypermethylation Is Common but INK4a-ARF Locus or p53 Mutations Are Rare in Merkel Cell Carcinoma

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCP.22431

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13 September 2017

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