(Q39659284)

13 September 2017

Interfering with RAS-effector protein interactions prevent RAS-dependent tumour initiation and causes stop-start control of cancer growth (English)

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13 September 2017

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T Tanaka

1

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13 September 2017

T H Rabbitts

series ordinal

2

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13 September 2017

language of work or name

English

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publication date

6 September 2010

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13 September 2017

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13 September 2017

29

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13 September 2017

45

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13 September 2017

6064-6070

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https://scigraph.springernature.com/pub.10.1038/onc.2010.346

13 September 2017

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cites work

Stable suppression of tumorigenicity by virus-mediated RNA interference

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Essential role for oncogenic Ras in tumour maintenance

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A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors

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Targeting RAS signalling pathways in cancer therapy

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Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.

21 January 2018

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Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

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A change of strategy in the war on cancer.

21 January 2018

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Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.346

Ras-effector interactions: after one decade

21 January 2018

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Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

21 January 2018

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Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

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Ras oncogenes: split personalities

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Identification of bronchioalveolar stem cells in normal lung and lung cancer

21 January 2018

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Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene

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The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

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Impact of oncogenes in tumor angiogenesis: mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells

21 January 2018

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Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

21 January 2018

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Loss of oncogenic ras expression does not correlate with loss of tumorigenicity in human cells

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Oncogene addiction: setting the stage for molecularly targeted cancer therapy

21 January 2018

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Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

21 January 2018

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Generalized lacZ expression with the ROSA26 Cre reporter strain

21 January 2018

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Tumour prevention by a single antibody domain targeting the interaction of signal transduction proteins with RAS

21 January 2018

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The guanine nucleotide-binding switch in three dimensions

21 January 2018

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Cancer. Addiction to oncogenes--the Achilles heal of cancer

21 January 2018

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Somatic alterations in the human cancer genome

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/ONC.2010.346

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Dimensions Publication ID

13 September 2017

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