(Q35064547)

6 August 2017

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title

Ras-effector interactions: after one decade (English)

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6 August 2017

Christian Herrmann

1

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6 August 2017

1 February 2003

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Current Opinion in Structural Biology

6 August 2017

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6 August 2017

13

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6 August 2017

1

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6 August 2017

122-129

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Rho GTPases and their effector proteins

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

RHO-GTPases and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Ypt and Rab GTPases: insight into functions through novel interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Transport into and out of the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Crystal structure of a dynamin GTPase domain in both nucleotide-free and GDP-bound forms

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Conformational transitions in p21ras and in its complexes with the effector protein Raf-RBD and the GTPase activating protein GAP.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Regional polysterism in the GTP-bound form of the human c-Ha-Ras protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

The RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

GTP-dependent segregation of H-ras from lipid rafts is required for biological activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Three-dimensional structure of the Ras-interacting domain of RalGDS

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Solution structure of the Ras-binding domain of RGL

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Structure determination of the Ras-binding domain of the Ral-specific guanine nucleotide exchange factor Rlf

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Structural insights into phosphoinositide 3-kinase catalysis and signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Solution structure of the Ras binding domain of the protein kinase Byr2 from Schizosaccharomyces pombe

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Structural basis for the interaction of Ras with RalGDS

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Structural and biochemical analysis of Ras-effector signaling via RalGDS

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

The Ras-Byr2RBD complex: structural basis for Ras effector recognition in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

A novel family of Ras-binding domains.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

SMART, a simple modular architecture research tool: identification of signaling domains

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Recent improvements to the SMART domain-based sequence annotation resource

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Ras-binding domains: predicting function versus folding

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Critical function of the Ras-associating domain as a primary Ras-binding site for regulation of Saccharomyces cerevisiae adenylyl cyclase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

A homochiral metal-organic porous material for enantioselective separation and catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Flipping the switch: the structural basis for signaling through the CRIB motif

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Structural view of the Ran-Importin beta interaction at 2.3 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

The guanine nucleotide-binding switch in three dimensions

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

The mammalian Rab family of small GTPases: definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

The many faces of Ras: recognition of small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

The atomic structure of protein-protein recognition sites

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Thermodynamics of Ras/effector and Cdc42/effector interactions probed by isothermal titration calorimetry

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Signaling pathways in Ras-mediated tumorigenicity and metastasis.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Effector recognition by the small GTP-binding proteins Ras and Ral

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Double-Mutant Analysis of the Interaction of Ras with the Ras-Binding Domain of RGL†

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Transient Kinetic Studies on the Interaction of Ras and the Ras-Binding Domain of c-Raf-1 Reveal Rapid Equilibration of the Complex†

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

The activation of RalGDS can be achieved independently of its Ras binding domain. Implications of an activation mechanism in Ras effector specificity and signal distribution

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Dynamic properties of the Ras switch I region and its importance for binding to effectors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

c-Raf-1 RBD associates with a subset of active v-H-Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Minimal catalytic domain of a group I self-splicing intron RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

High-pressure NMR study of the complex of a GTPase Rap1A with its effector RalGDS. A conformational switch in RalGDS revealed from non-linear pressure shifts.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Low-lying excited states of proteins revealed from nonlinear pressure shifts in 1H and 15N NMR.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Two folded conformers of ubiquitin revealed by high-pressure NMR

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

MOLMOL: a program for display and analysis of macromolecular structures

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Galectin-1 Augments Ras Activation and Diverts Ras Signals to Raf-1 at the Expense of Phosphoinositide 3-Kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

Activation of phosphoinositide 3-kinase gamma by Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900007-6

7 January 2021

10.1016/S0959-440X(02)00007-6

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12581669