(Q39664652)

13 September 2017

title

The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program (English)

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13 September 2017

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L Schneider

2

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author name string

S Schmidt

1

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13 September 2017

F Essmann

3

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13 September 2017

I C Cirstea

4

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13 September 2017

F Kuck

5

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13 September 2017

A Kletke

6

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13 September 2017

R U Jänicke

7

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13 September 2017

C Wiek

8

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13 September 2017

H Hanenberg

9

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13 September 2017

M R Ahmadian

10

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13 September 2017

K Schulze-Osthoff

11

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13 September 2017

B Nürnberg

12

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13 September 2017

R P Piekorz

13

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13 September 2017

language of work or name

English

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publication date

23 August 2010

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13 September 2017

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13 September 2017

volume

29

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13 September 2017

issue

46

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13 September 2017

page(s)

6184-6192

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The signals and pathways activating cellular senescence

13 September 2017

cites work

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CENP-A phosphorylation by Aurora-A in prophase is required for enrichment of Aurora-B at inner centromeres and for kinetochore function

21 January 2018

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Aberrations of TACC1 and TACC3 are associated with ovarian cancer

21 January 2018

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Downregulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not etoposide or cisplatin-induced cell death

21 January 2018

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Apoptosis in the absence of caspase 3.

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CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses

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The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis

21 January 2018

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Cellular senescence induced by aberrant MAD2 levels impacts on paclitaxel responsiveness in vitro

21 January 2018

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If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells

21 January 2018

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Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

21 January 2018

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TACC3 depletion sensitizes to paclitaxel-induced cell death and overrides p21WAF-mediated cell cycle arrest

21 January 2018

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The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival

21 January 2018

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The centrosomal, putative tumor suppressor protein TACC2 is dispensable for normal development, and deficiency does not lead to cancer

21 January 2018

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Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5.

21 January 2018

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Inhibition of centrosome protein assembly leads to p53-dependent exit from the cell cycle.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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HP1 proteins are essential for a dynamic nuclear response that rescues the function of perturbed heterochromatin in primary human cells.

21 January 2018

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21 January 2018

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Apaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment

21 January 2018

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Expression of transforming acidic coiled-coil containing protein 3 is a novel independent prognostic marker in non-small cell lung cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.354

Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.354

Regulatory phosphorylation of Bim: sorting out the ERK from the JNK

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.354

TACC3 is required for the proper mitosis of sclerotome mesenchymal cells during formation of the axial skeleton

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.354

1 reference

13 September 2017

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