(Q39664652)

13 September 2017

The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program (English)

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13 September 2017

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L Schneider

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author name string

S Schmidt

1

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13 September 2017

F Essmann

3

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13 September 2017

I C Cirstea

4

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13 September 2017

F Kuck

5

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13 September 2017

A Kletke

6

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13 September 2017

R U Jänicke

7

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13 September 2017

C Wiek

8

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13 September 2017

H Hanenberg

9

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13 September 2017

M R Ahmadian

10

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13 September 2017

K Schulze-Osthoff

11

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13 September 2017

B Nürnberg

12

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13 September 2017

R P Piekorz

13

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13 September 2017

language of work or name

English

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publication date

23 August 2010

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13 September 2017

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13 September 2017

29

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13 September 2017

6184-6192

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13 September 2017

46

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https://scigraph.springernature.com/pub.10.1038/onc.2010.354

13 September 2017

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cites work

The signals and pathways activating cellular senescence

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Cell senescence: hypertrophic arrest beyond the restriction point

21 January 2018

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Prolonged mitosis versus tetraploid checkpoint: how p53 measures the duration of mitosis.

21 January 2018

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Cytostatic activity of paclitaxel in coronary artery smooth muscle cells is mediated through transient mitotic arrest followed by permanent post-mitotic arrest: comparison with cancer cells

21 January 2018

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Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint

21 January 2018

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p21(Waf1/Cip1/Sdi1) mediates retinoblastoma protein degradation.

21 January 2018

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ERK and cell death: mechanisms of ERK-induced cell death--apoptosis, autophagy and senescence

21 January 2018

1 reference

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Cellular senescence: when bad things happen to good cells

21 January 2018

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TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly

21 January 2018

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The power and the promise of oncogene-induced senescence markers.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.354

Bim is reversibly phosphorylated but plays a limited role in paclitaxel cytotoxicity of breast cancer cell lines

21 January 2018

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Mechanism of G1-like arrest by low concentrations of paclitaxel: next cell cycle p53-dependent arrest with sub G1 DNA content mediated by prolonged mitosis

21 January 2018

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Apoptosis resistance of MCF-7 breast carcinoma cells to ionizing radiation is independent of p53 and cell cycle control but caused by the lack of caspase-3 and a caffeine-inhibitable event

21 January 2018

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Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs.

21 January 2018

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PEA-15 is inhibited by adenovirus E1A and plays a role in ERK nuclear export and Ras-induced senescence

21 January 2018

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21 January 2018

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The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells

21 January 2018

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Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies

21 January 2018

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Examining the mechanism of Erk nuclear translocation using green fluorescent protein

21 January 2018

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MLN8054, an inhibitor of Aurora A kinase, induces senescence in human tumor cells both in vitro and in vivo

21 January 2018

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Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

21 January 2018

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SAC-ing mitotic errors: how the spindle assembly checkpoint (SAC) plays defense against chromosome mis-segregation

21 January 2018

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The nature of cell-cycle checkpoints: facts and fallacies

21 January 2018

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A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer

21 January 2018

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The regulation of INK4/ARF in cancer and aging

21 January 2018

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Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence

21 January 2018

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CENP-A phosphorylation by Aurora-A in prophase is required for enrichment of Aurora-B at inner centromeres and for kinetochore function

21 January 2018

1 reference

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Aberrations of TACC1 and TACC3 are associated with ovarian cancer

21 January 2018

1 reference

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Downregulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not etoposide or cisplatin-induced cell death.

21 January 2018

1 reference

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Apoptosis in the absence of caspase 3.

21 January 2018

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CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses

21 January 2018

1 reference

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Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest

21 January 2018

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Microtubules, microtubule-interfering agents and apoptosis.

21 January 2018

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Critical requirement for cell cycle inhibitors in sustaining nonproliferative states.

21 January 2018

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The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis

21 January 2018

1 reference

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Cellular senescence induced by aberrant MAD2 levels impacts on paclitaxel responsiveness in vitro

21 January 2018

1 reference

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If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

TACC3 depletion sensitizes to paclitaxel-induced cell death and overrides p21WAF-mediated cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

The centrosomal, putative tumor suppressor protein TACC2 is dispensable for normal development, and deficiency does not lead to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

Inhibition of centrosome protein assembly leads to p53-dependent exit from the cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

Microtubule binding and disruption and induction of premature senescence by disorazole C(1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

ERK MAP kinase in G cell cycle progression and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

Modulation of replicative senescence of diploid human cells by nuclear ERK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

The transcriptional targets of p53 in apoptosis control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

HP1 proteins are essential for a dynamic nuclear response that rescues the function of perturbed heterochromatin in primary human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

Centrosome function in cancer: guilty or innocent?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

Apaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

Expression of transforming acidic coiled-coil containing protein 3 is a novel independent prognostic marker in non-small cell lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

Regulatory phosphorylation of Bim: sorting out the ERK from the JNK

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

TACC3 is required for the proper mitosis of sclerotome mesenchymal cells during formation of the axial skeleton

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.354

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.354

1 reference

13 September 2017

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