(Q39674366)

13 September 2017

title

PIM kinase inhibitors downregulate STAT3(Tyr705) phosphorylation (English)

1 reference

13 September 2017

PIM Kinase Inhibitors Downregulate STAT3Tyr705 Phosphorylation (English)

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

12 June 2024

author name string

Marisa Chang

1

1 reference

13 September 2017

Nisha Kanwar

2

1 reference

13 September 2017

Eric Feng

3

1 reference

13 September 2017

Allan Siu

4

1 reference

13 September 2017

Xiujie Liu

5

1 reference

13 September 2017

Dawei Ma

6

1 reference

13 September 2017

Jan Jongstra

7

1 reference

13 September 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20667852

12 June 2024

publication date

28 July 2010

1 reference

full work available at URL

13 September 2017

https://aacrjournals.org/mct/article-pdf/9/9/2478/1889688/2478.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20667852

http://intl-mct.aacrjournals.org/cgi/content/abstract/9/9/2478

12 June 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20667852

https://aacrjournals.org/mct/article-pdf/9/9/2478/1889688/2478.pdf

12 June 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Molecular Cancer Therapeutics

12 June 2024

published in

1 reference

13 September 2017

volume

9

1 reference

13 September 2017

issue

9

1 reference

13 September 2017

page(s)

2478-2487

1 reference

Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region

13 September 2017

cites work

1

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc

12 June 2024

4

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

12 June 2024

5

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Overexpression of Pim-1 during progression of prostatic adenocarcinoma

12 June 2024

6

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Pim-2 upregulation: biological implications associated with disease progression and perinueral invasion in prostate cancer

12 June 2024

7

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Pim-3, a proto-oncogene with serine/threonine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates bad to block bad-mediated apoptosis in human pancreatic cancer cell lines

12 June 2024

9

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad-mediated apoptosis

12 June 2024

10

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Accelerated hepatocellular carcinoma development in mice expressing the Pim-3 transgene selectively in the liver

12 June 2024

11

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Pim family kinases enhance tumor growth of prostate cancer cells

12 June 2024

12

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels

12 June 2024

13

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase

12 June 2024

14

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

The serine/threonine kinase Pim-1

12 June 2024

15

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site

12 June 2024

16

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis

12 June 2024

17

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Potential roles for the PIM1 kinase in human cancer - a molecular and therapeutic appraisal

12 June 2024

18

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Mechanisms of disease: Insights into the emerging role of signal transducers and activators of transcription in cancer

12 June 2024

19

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

STATs in cancer inflammation and immunity: a leading role for STAT3

12 June 2024

20

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

12 June 2024

21

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Clinical and pathologic significance of activation of signal transducer and activator of transcription 3 in prostate cancer

12 June 2024

22

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells

12 June 2024

23

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer.

12 June 2024

24

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Circulating levels of interleukin-6 in patients with hormone refractory prostate cancer

12 June 2024

25

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Characterization of the role of IL-6 in the progression of prostate cancer

12 June 2024

26

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Signal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines

12 June 2024

27

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

RNA interference targeting Stat3 inhibits growth and induces apoptosis of human prostate cancer cells.

12 June 2024

28

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Inhibition of constitutively activated Stat3 signaling pathway suppresses growth of prostate cancer cells

12 June 2024

29

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes

12 June 2024

30

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Inhibition of anti-IgM-induced translocation of protein kinase C beta I inhibits ERK2 activation and increases apoptosis

12 June 2024

31

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

LSP1 regulates anti-IgM induced apoptosis in WEHI-231 cells and normal immature B-cells

12 June 2024

32

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

New colorimetric cytotoxicity assay for anticancer-drug screening

12 June 2024

33

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Leukocyte-specific protein 1 targets the ERK/MAP kinase scaffold protein KSR and MEK1 and ERK2 to the actin cytoskeleton

12 June 2024

34

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

A rapid method for determining protein kinase phosphorylation specificity

12 June 2024

35

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Targeting the WNT/beta-catenin/TCF/LEF1 axis in solid and haematological cancers: Multiplicity of therapeutic options

12 June 2024

36

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells

12 June 2024

37

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

WP1066, a novel JAK2 inhibitor, suppresses proliferation and induces apoptosis in erythroid human cells carrying the JAK2 V617F mutation

12 June 2024

38

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Epidemiology of prostate cancer

12 June 2024

39

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Estimates of the cancer incidence and mortality in Europe in 2006.

12 June 2024

40

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the TAX 327 study

12 June 2024

41

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Pim serine/threonine kinases regulate the stability of Socs-1 protein

12 June 2024

42

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Pim-1 kinase inhibits STAT5-dependent transcription via its interactions with SOCS1 and SOCS3.

12 June 2024

43

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Down-regulation of suppressor of cytokine signaling-3 causes prostate cancer cell death through activation of the extrinsic and intrinsic apoptosis pathways

12 June 2024

44

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Suppressor of cytokine signaling (SOCS)-1 is expressed in human prostate cancer and exerts growth-inhibitory function through down-regulation of cyclins and cyclin-dependent kinases

12 June 2024

45

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors

12 June 2024

47

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

The function of Stat3 in tumor cells and their microenvironment

12 June 2024

48

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

The 44 kDa Pim-1 kinase directly interacts with tyrosine kinase Etk/BMX and protects human prostate cancer cells from apoptosis induced by chemotherapeutic drugs

12 June 2024

49

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

Pim-1 negatively regulates the activity of PTP-U2S phosphatase and influences terminal differentiation and apoptosis of monoblastoid leukemia cells

12 June 2024

50

1 reference

https://api.crossref.org/works/10.1158/1535-7163.MCT-10-0321

12 June 2024

Identifiers

1 reference

13 September 2017

1 reference