(Q39674980)

English

Identification by High-Throughput Screening of Viridin Analogs as Biochemical and Cell-Based Inhibitors of the Cell Cycle–Regulated Nek2 Kinase

scientific article published on July 27, 2010

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scholarly article

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Europe PubMed Central

PMC publication ID

13 September 2017

Identification by high-throughput screening of viridin analogs as biochemical and cell-based inhibitors of the cell cycle-regulated nek2 kinase (English)

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Identification by High-Throughput Screening of Viridin Analogs as Biochemical and Cell-Based Inhibitors of the Cell Cycle–Regulated Nek2 Kinase (English)

1 reference

10.1177/1087057110376537

https://api.crossref.org/works/10.1177/1087057110376537

11 June 2024

8

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Paul Workman

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Europe PubMed Central

13 September 2017

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Yvette Newbatt

2

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Europe PubMed Central

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13 September 2017

Lisa Pickard

3

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Europe PubMed Central

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13 September 2017

Eilis Byrne

4

1 reference

Europe PubMed Central

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13 September 2017

Guojie Mao

5

1 reference

Europe PubMed Central

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13 September 2017

Samantha Burns

6

1 reference

Europe PubMed Central

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13 September 2017

Ian Collins

9

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Wynne Aherne

10

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Europe PubMed Central

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13 September 2017

Daniel G. Hayward

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20664067

11 June 2024

Navdeep K. Sahota

7

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20664067

11 June 2024

Andrew M. Fry

11

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Europe PubMed Central

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11 June 2024

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20664067

11 June 2024

publication date

27 July 2010

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Europe PubMed Central

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13 September 2017

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https://journals.sagepub.com/doi/pdf/10.1177/1087057110376537

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20664067

11 June 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20664067/?tool=EBI

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Europe PubMed Central

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11 June 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20664067/pdf/?tool=EBI

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1 reference

Europe PubMed Central

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11 June 2024

http://jbx.sagepub.com/cgi/content/abstract/15/8/918

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Europe PubMed Central

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11 June 2024

https://europepmc.org/articles/PMC3947748

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Europe PubMed Central

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20664067

11 June 2024

https://europepmc.org/articles/PMC3947748?pdf=render

Portable Document Format

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Europe PubMed Central

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20664067

11 June 2024

https://doi.org/10.1177/1087057110376537

online access status

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20664067

11 June 2024

http://journals.sagepub.com/doi/pdf/10.1177/1087057110376537

1 reference

10.1177/1087057110376537

https://api.crossref.org/works/10.1177/1087057110376537

11 June 2024

http://journals.sagepub.com/doi/full-xml/10.1177/1087057110376537

1 reference

10.1177/1087057110376537

https://api.crossref.org/works/10.1177/1087057110376537

11 June 2024

https://api.elsevier.com/content/article/PII:S2472555222079795?httpAccept=text/xml

1 reference

10.1177/1087057110376537

https://api.crossref.org/works/10.1177/1087057110376537

11 June 2024

https://api.elsevier.com/content/article/PII:S2472555222079795?httpAccept=text/plain

1 reference

10.1177/1087057110376537

https://api.crossref.org/works/10.1177/1087057110376537

11 June 2024

Journal of Biomolecular Screening

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

15

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

8

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

918-927

1 reference

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PMC publication ID

13 September 2017

Drugging the PI3 kinome: from chemical tools to drugs in the clinic.

1 reference

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14 September 2017

Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2

1 reference

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14 September 2017

Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease

1 reference

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14 September 2017

Insights into the Conformational Variability and Regulation of Human Nek2 Kinase

1 reference

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14 September 2017

Mitotic regulation by NIMA-related kinases

1 reference

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14 September 2017

Targeting cell cycle kinases for cancer therapy

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14 September 2017

Structure and regulation of the human Nek2 centrosomal kinase

1 reference

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14 September 2017

Development and comparison of nonradioactive in vitro kinase assays for NIMA-related kinase 2.

1 reference

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14 September 2017

Nek2 kinase in chromosome instability and cancer

1 reference

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14 September 2017

Array comparative genomic hybridization analysis of genomic alterations in breast cancer subtypes

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14 September 2017

N2-substituted O6-cyclohexylmethylguanine derivatives: potent inhibitors of cyclin-dependent kinases 1 and 2

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14 September 2017

Identification of a novel class of orally active pyrimido[5,4-3][1,2,4]triazine-5,7-diamine-based hypoglycemic agents with protein tyrosine phosphatase inhibitory activity

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14 September 2017

Nek2A kinase stimulates centrosome disjunction and is required for formation of bipolar mitotic spindles

1 reference

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The Nek2 protein kinase: a novel regulator of centrosome structure

1 reference

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Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

1 reference

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

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14 September 2017

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

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14 September 2017

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

1 reference

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Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues

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14 September 2017

Nek2 as a novel molecular target for the treatment of breast carcinoma

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14 September 2017

Increased expression and nuclear localization of the centrosomal kinase Nek2 in human testicular seminomas

1 reference

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Nek2 as an effective target for inhibition of tumorigenic growth and peritoneal dissemination of cholangiocarcinoma

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The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer

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Effect of detergent on "promiscuous" inhibitors

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Substrate specificity and cell cycle regulation of the Nek2 protein kinase, a potential human homolog of the mitotic regulator NIMA of Aspergillus nidulans.

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Live cell imaging reveals distinct roles in cell cycle regulation for Nek2A and Nek2B.

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12 December 2020

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10.1177/1087057110376537

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

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