(Q39682306)

English

Triggering Ras signalling by intracellular Francisella tularensis through recruitment of PKCα and βI to the SOS2/GrB2 complex is essential for bacterial proliferation in the cytosol

scientific article published on November 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Triggering Ras signalling by intracellular Francisella tularensis through recruitment of PKCα and βI to the SOS2/GrB2 complex is essential for bacterial proliferation in the cytosol (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Francisella tularensis

object named as

Francisella tularensis

1 reference

based on heuristic

inferred from title

Souhaila Al-Khodor

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Yousef Abu Kwaik

2

object named as

Yousef Abu Kwaik

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

publication date

1 November 2010

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Europe PubMed Central

PubMed publication ID

13 September 2017

Cellular Microbiology

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

1604-1621

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Host factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol

1 reference

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Oncogenic ras-induced expression of cytokines: a new target of anti-cancer therapeutics

1 reference

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Molecular complexity orchestrates modulation of phagosome biogenesis and escape to the cytosol of macrophages by Francisella tularensis

1 reference

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21 January 2018

Molecular bases of proliferation of Francisella tularensis in arthropod vectors

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The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence.

1 reference

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21 January 2018

Proteins regulating Ras and its relatives

1 reference

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A conserved alpha-helix essential for a type VI secretion-like system of Francisella tularensis

1 reference

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21 January 2018

The Francisella pathogenicity island protein IglA localizes to the bacterial cytoplasm and is needed for intracellular growth

1 reference

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21 January 2018

Francisella tularensis induces IL-23 production in human monocytes

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21 January 2018

Microarray analysis of human monocytes infected with Francisella tularensis identifies new targets of host response subversion

1 reference

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Oncogenic Ras signals through activation of both phosphoinositide 3-kinase and Rac1 to induce c-Jun NH2-terminal kinase-mediated, caspase-independent cell death

1 reference

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Increasing complexity of Ras signaling.

1 reference

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Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies

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21 January 2018

Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication

1 reference

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Requirement of p21-activated kinase (PAK) for Salmonella typhimurium-induced nuclear responses

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Virulent and avirulent strains of Francisella tularensis prevent acidification and maturation of their phagosomes and escape into the cytoplasm in human macrophages

1 reference

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21 January 2018

Francisella tularensis enters macrophages via a novel process involving pseudopod loops

1 reference

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MiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine response

1 reference

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Francisella tularensis regulates autophagy-related host cell signaling pathways

1 reference

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Threats in bioterrorism. I: CDC category A agents

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Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

1 reference

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21 January 2018

Guanine-nucleotide exchange factors: a family of positive regulators of Ras and related GTPases

1 reference

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21 January 2018

Analysis of 16S ribosomal DNA sequences of Francisella strains and utilization for determination of the phylogeny of the genus and for identification of strains by PCR.

1 reference

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21 January 2018

Internalization and phagosome escape required for Francisella to induce human monocyte IL-1beta processing and release

1 reference

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21 January 2018

The identification of five genetic loci of Francisella novicida associated with intracellular growth

1 reference

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21 January 2018

Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases

1 reference

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21 January 2018

Novel Ras pathway inhibitor induces apoptosis and growth inhibition of K-ras-mutated cancer cells in vitro and in vivo

1 reference

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21 January 2018

A novel quinoline, MT477: suppresses cell signaling through Ras molecular pathway, inhibits PKC activity, and demonstrates in vivo anti-tumor activity against human carcinoma cell lines

1 reference

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A Ras activation pathway dependent on Syk phosphorylation of protein kinase C

1 reference

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21 January 2018

Molecular epidemiology, evolution, and ecology of Francisella

1 reference

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Francisella tularensis induces cytopathogenicity and apoptosis in murine macrophages via a mechanism that requires intracellular bacterial multiplication

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2010.01494.X

21 January 2018

Expression of IglC is necessary for intracellular growth and induction of apoptosis in murine macrophages by Francisella tularensis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2010.01494.X

21 January 2018

Allelic exchange in Francisella tularensis using PCR products

1 reference

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21 January 2018

MglA regulates transcription of virulence factors necessary for Francisella tularensis intraamoebae and intramacrophage survival

1 reference

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21 January 2018

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1 reference

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Internalin B activates nuclear factor-kappa B via Ras, phosphoinositide 3-kinase, and Akt.

1 reference

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Grb2 is a key mediator of helicobacter pylori CagA protein activities

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Identification of two novel activities of the Wnt signaling regulator Dickkopf 3 and characterization of its expression in the mouse retina

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21 January 2018

Intranasal vaccination with a defined attenuated Francisella novicida strain induces gamma interferon-dependent antibody-mediated protection against tularemia

1 reference

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21 January 2018

Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2010.01494.X

21 January 2018

The tyrosine kinase Syk promotes phagocytosis of Francisella through the activation of Erk

1 reference

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Working toward the future: insights into Francisella tularensis pathogenesis and vaccine development

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Constitutive activation of the Ras/MAP kinase pathway and enhanced TCR signaling by targeting the Shc adaptor to membrane rafts

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Molecular mimicry by an F-box effector of Legionella pneumophila hijacks a conserved polyubiquitination machinery within macrophages and protozoa

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Akt and SHIP modulate Francisella escape from the phagosome and induction of the Fas-mediated death pathway

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Contribution of PKC-dependent and -independent processes in temporal ERK regulation by ET-1, PDGF, and EGF in rat myometrial cells

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Modulation of biogenesis of the Francisella tularensis subsp. novicida-containing phagosome in quiescent human macrophages and its maturation into a phagolysosome upon activation by IFN-gamma.

1 reference

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The Francisella tularensis pathogenicity island protein IglC and its regulator MglA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm.

1 reference

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Acquisition of the vacuolar ATPase proton pump and phagosome acidification are essential for escape of Francisella tularensis into the macrophage cytosol.

1 reference

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21 January 2018

Regulation of apoptosis and anti-apoptosis signalling by Francisella tularensis.

1 reference

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Cell biology and molecular ecology of Francisella tularensis.

1 reference

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Francisella tularensis inhibits Toll-like receptor-mediated activation of intracellular signalling and secretion of TNF-alpha and IL-1 from murine macrophages

1 reference

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Francisella tularensis LVS initially activates but subsequently down-regulates intracellular signaling and cytokine secretion in mouse monocytic and human peripheral blood mononuclear cells

1 reference

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Attenuated Francisella novicida transposon mutants protect mice against wild-type challenge

1 reference

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21 January 2018

Intracellular biology and virulence determinants of Francisella tularensis revealed by transcriptional profiling inside macrophages

1 reference

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21 January 2018

Francisella tularensis induces extensive caspase-3 activation and apoptotic cell death in the tissues of infected mice

1 reference

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Vascular Endothelial Growth Factor Induction of the Angiogenic Phenotype Requires Ras Activation

1 reference

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The hunt for Ras targets

1 reference

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21 January 2018

Identifiers

10.1111/J.1462-5822.2010.01494.X

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

ResearchGate publication ID

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