(Q39706027)

14 September 2017

Hdm2 negatively regulates telomerase activity by functioning as an E3 ligase of hTERT. (English)

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14 September 2017

W Oh

1

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14 September 2017

E-W Lee

2

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14 September 2017

D Lee

3

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14 September 2017

M-R Yang

4

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14 September 2017

A Ko

5

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14 September 2017

C-H Yoon

6

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14 September 2017

H-W Lee

7

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14 September 2017

Y-S Bae

8

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14 September 2017

C Y Choi

9

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14 September 2017

J Song

10

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14 September 2017

language of work or name

English

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publication date

10 May 2010

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14 September 2017

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14 September 2017

29

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14 September 2017

28

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14 September 2017

4101-4112

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https://scigraph.springernature.com/pub.10.1038/onc.2010.160

14 September 2017

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cites work

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Extension of life-span by introduction of telomerase into normal human cells

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Murine double minute 2: p53-independent roads lead to genome instability or death

21 January 2018

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p53 ubiquitination: Mdm2 and beyond

21 January 2018

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Telomerase redefined: integrated regulation of hTR and hTERT for telomere maintenance and telomerase activity

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Ubiquitin-independent degradation of p53 mediated by high-risk human papillomavirus protein E6.

21 January 2018

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Actions of human telomerase beyond telomeres

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Human telomerase and its regulation

21 January 2018

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Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase

21 January 2018

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Oxidative stress pathways highlighted in tumor cell immortalization: association with breast cancer outcome

21 January 2018

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Shelterin: the protein complex that shapes and safeguards human telomeres

21 January 2018

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MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53

21 January 2018

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Mdm2 exerts pro-apoptotic activities by antagonizing insulin-like growth factor-I-mediated survival

21 January 2018

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Creation of human tumour cells with defined genetic elements

21 January 2018

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Telomerase and cancer therapeutics

21 January 2018

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Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT.

21 January 2018

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Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP).

21 January 2018

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Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

21 January 2018

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Connecting chromosomes, crisis, and cancer

21 January 2018

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Telomeres and their control

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.160

PML-IV functions as a negative regulator of telomerase by interacting with TERT

21 January 2018

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Jab1 induces the cytoplasmic localization and degradation of p53 in coordination with Hdm2.

21 January 2018

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hTERT antagonizes p53-induced apoptosis independently of telomerase activity.

21 January 2018

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Increased apoptosis induction by 121F mutant p53

21 January 2018

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p53-dependent down-regulation of telomerase is mediated by p21waf1.

21 January 2018

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Antisense hTERT inhibits thyroid cancer cell growth

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Role of telomerase in cell senescence and oncogenesis

21 January 2018

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Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16 E6 oncoprotein

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.160

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.160

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.160

p53-independent activities of MDM2 and their relevance to cancer therapy

21 January 2018

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TERT regulates cell survival independent of telomerase enzymatic activity

21 January 2018

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Regulation of Angiogenic Factors by HDM2 in Renal Cell Carcinoma

31 March 2020

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TRAP-silver staining, a highly sensitive assay for measuring telomerase activity in tumor tissue and cell lines

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.160

Ectopic hTERT expression extends the life span of human CD4+ helper and regulatory T-cell clones and confers resistance to oxidative stress-induced apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.160

Telomerase levels control the lifespan of human T lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.160

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.160

Immunodetection of human telomerase reverse-transcriptase (hTERT) re-appraised: nucleolin and telomerase cross paths

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.160

Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.160

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.160

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14 September 2017

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