(Q39711541)

English

Age-related deregulation of Aire and peripheral tissue antigen genes in the thymic stroma of non-obese diabetic (NOD) mice is associated with autoimmune type 1 diabetes mellitus (DM-1).

scientific article published on 23 April 2010

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Europe PubMed Central

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1 February 2020

Age-related deregulation of Aire and peripheral tissue antigen genes in the thymic stroma of non-obese diabetic (NOD) mice is associated with autoimmune type 1 diabetes mellitus (DM-1) (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20414703%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

type-1 diabetes

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Geraldo A. Passos

6

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Europe PubMed Central

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1 February 2020

Marcia Martins Marques

4

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1 February 2020

Paula B. Donate

2

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Paula B Donate

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Europe PubMed Central

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1 February 2020

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Thaís A Fornari

1

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1 February 2020

Claudia Macedo

3

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1 February 2020

Danielle A Magalhães

5

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Europe PubMed Central

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1 February 2020

publication date

23 April 2010

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Europe PubMed Central

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1 February 2020

Molecular and Cellular Biochemistry

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20414703%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

342

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Europe PubMed Central

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1 February 2020

1-2

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1 February 2020

21-28

1 reference

Europe PubMed Central

PubMed publication ID

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1 February 2020

A novel form of cellular communication among thymic epithelial cells: intercellular calcium wave propagation

1 reference

https://api.crossref.org/works/10.1007%2FS11010-010-0464-Z

21 January 2018

Highly variable expression of tissue-restricted self-antigens in human thymus: implications for self-tolerance and autoimmunity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cluster analysis and display of genome-wide expression patterns

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Journey through the thymus: stromal guides for T-cell development and selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A central role for central tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positional cloning of the APECED gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Onset of promiscuous gene expression in murine fetal thymus organ culture.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-representation in the thymus: an extended view

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiated

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different patterns of nicotinic acetylcholine receptor subunit transcription in human thymus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of Aire regulates the expression of tissue-restricted antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promiscuous gene expression and central T-cell tolerance: more than meets the eye.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large-scale analysis of the human and mouse transcriptomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modifier loci condition autoimmunity provoked by Aire deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic and pathogenic basis of autoimmune diabetes in NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aire: an update.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A concise guide to cDNA microarray analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoimmune regulator: from loss of function to autoimmunity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NOD mouse model of type 1 diabetes: as good as it gets?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central tolerance: good but imperfect

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Back to central tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aire deficient mice develop multiple features of APECED phenotype and show altered immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profiling during thymus ontogeny and its association with TCRVbeta8.1-Dbeta2.1 rearrangements of inbred mouse strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a network transcriptional control of promiscuous gene expression in medullary thymic epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of thymic stromal cell populations using flow cytometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple sclerosis candidate autoantigens except myelin oligodendrocyte glycoprotein are transcribed in human thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promiscuous gene expression in the thymus: the root of central tolerance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Claudins provide a breath of fresh Aire

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance analysis of microarrays applied to the ionizing radiation response

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-antigen presentation by thymic stromal cells: a subtle division of labor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NOD mouse: a model of immune dysregulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-010-0464-Z

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20414703%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20414703%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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