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FKBP38 protects Bcl-2 from caspase-dependent degradation.
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Europe PubMed Central
PMC publication ID
2843226
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139069%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
title
FKBP38 protects Bcl-2 from caspase-dependent degradation
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2843226
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139069%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author
Ho Sup Yoon
series ordinal
3
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Europe PubMed Central
PMC publication ID
2843226
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139069%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author name string
Bo-Hwa Choi
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
2843226
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139069%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Lin Feng
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2843226
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139069%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
language of work or name
English
0 references
publication date
5 February 2010
1 reference
stated in
Europe PubMed Central
PMC publication ID
2843226
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139069%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
published in
Journal of Biological Chemistry
1 reference
stated in
Europe PubMed Central
PMC publication ID
2843226
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139069%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
volume
285
1 reference
stated in
Europe PubMed Central
PMC publication ID
2843226
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139069%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
issue
13
1 reference
stated in
Europe PubMed Central
PMC publication ID
2843226
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139069%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
page(s)
9770-9779
1 reference
stated in
Europe PubMed Central
PMC publication ID
2843226
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139069%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
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S-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation - a novel antiapoptotic mechanism that suppresses apoptosis
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Molecular characterization of FK-506 binding protein 38 and its potential regulatory role on the anti-apoptotic protein Bcl-2
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Bcl-2 regulator FKBP38 is activated by Ca2+/calmodulin
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The flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38)
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FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues
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Functional identification of distinct sets of antitumor activities mediated by the FKBP gene family
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Cell size regulation by the human TSC tumor suppressor proteins depends on PI3K and FKBP38
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Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis
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The Bcl2 family: regulators of the cellular life-or-death switch
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Novel anticancer drug discovery
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muFKBP38: a novel murine immunophilin homolog differentially expressed in Schwannoma cells and central nervous system neurons in vivo
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Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis
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14 September 2017
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
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14 September 2017
Kinetin riboside preferentially induces apoptosis by modulating Bcl-2 family proteins and caspase-3 in cancer cells.
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14 September 2017
Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843226
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14 September 2017
Anchoring of the 26S proteasome to the organellar membrane by FKBP38.
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14 September 2017
PS-341, a novel proteasome inhibitor, induces Bcl-2 phosphorylation and cleavage in association with G2-M phase arrest and apoptosis
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843226
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14 September 2017
NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843226
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25 September 2017
Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843226
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25 September 2017
Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843226
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25 September 2017
Conversion of Bcl-2 to a Bax-like death effector by caspases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843226
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25 September 2017
Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling
1 reference
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PubMed Central
reference URL
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15 June 2018
An informatics approach identifying markers of chemosensitivity in human cancer cell lines.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843226
retrieved
15 June 2018
Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843226
retrieved
15 June 2018
Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843226
retrieved
20 August 2018
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843226
retrieved
20 August 2018
Immunophilins in the nervous system
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20139069
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20139069
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Overlapping sites of tetratricopeptide repeat protein binding and chaperone activity in heat shock protein 90
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20139069
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Caspase-3 is essential for procaspase-9 processing and cisplatin-induced apoptosis of MCF-7 breast cancer cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20139069
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20139069
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Vitamin C and E prevent lipopolysaccharide-induced apoptosis in human endothelial cells by modulation of Bcl-2 and Bax
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20139069
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1074/JBC.M109.032466
1 reference
stated in
Europe PubMed Central
PMC publication ID
2843226
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139069%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PMC publication ID
2843226
1 reference
stated in
Europe PubMed Central
PMC publication ID
2843226
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139069%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PubMed publication ID
20139069
1 reference
stated in
Europe PubMed Central
PMC publication ID
2843226
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139069%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
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