(Q39741320)

14 September 2017

Lung cancers unrelated to smoking: characterized by single oncogene addiction? (English)

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14 September 2017

4

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14 September 2017

3

Yasushi Yatabe

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14 September 2017

1

Kenichi Suda

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14 September 2017

Kenji Tomizawa

2

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14 September 2017

8 June 2011

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International Journal of Clinical Oncology

14 September 2017

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14 September 2017

16

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14 September 2017

4

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14 September 2017

294-305

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https://scigraph.springernature.com/pub.10.1007/s10147-011-0262-y

14 September 2017

0 references

cites work

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

FDA drug approval summary: gefitinib (ZD1839) (Iressa) tablets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

The changing epidemiology of smoking and lung cancer histology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Korean ethnicity as compared with white ethnicity is an independent favorable prognostic factor for overall survival in non-small cell lung cancer before and after the oral epidermal growth factor receptor tyrosine kinase inhibitor era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Impact of smoking on cancer stage at diagnosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Lung cancer in never smokers--a different disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Lung cancer in never smokers: a call to action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Population attributable fraction of mortality associated with tobacco smoking in Japan: a pooled analysis of three large-scale cohort studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Lung cancer in never smokers: clinical epidemiology and environmental risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Somatic mutations affect key pathways in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Genomic aberrations in lung adenocarcinoma in never smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

The TP53 gene, tobacco exposure, and lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Dose effect of smoking on aberrant methylation in non-small cell lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Biological and clinical implications of EGFR mutations in lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Lung cancer: intragenic ERBB2 kinase mutations in tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Epidemiology of bronchioloalveolar carcinoma: improvement in survival after release of the 1999 WHO classification of lung tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Epidermal growth factor receptor mutation in lung cancer are linked to bronchioloalveolar differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

EGFR mutations and the terminal respiratory unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

TTF-1 expression in pulmonary adenocarcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

EGFR mutation is specific for terminal respiratory unit type adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Diversity of gene expression in adenocarcinoma of the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Non-Small-Cell Lung Cancer Molecular Signatures Recapitulate Lung Developmental Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Gene expression-based, individualized outcome prediction for surgically treated lung cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Expression profile-defined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Lung adenocarcinoma: modification of the 2004 WHO mixed subtype to include the major histologic subtype suggests correlations between papillary and micropapillary adenocarcinoma subtypes, EGFR mutations and gene expression analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Gene expression profiling of epidermal growth factor receptor/KRAS pathway activation in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Non-solid oncogenes in solid tumors: EML4-ALK fusion genes in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Inhibition of ALK, PI3K/MEK, and HSP90 in murine lung adenocarcinoma induced by EML4-ALK fusion oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

The histopathology of BRAF-V600E-mutated lung adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Impact of environmental tobacco smoke on the incidence of mutations in epidermal growth factor receptor gene in never-smoker patients with non-small-cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Previous lung diseases and lung cancer risk: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Novel germline mutation: EGFR V843I in patient with multiple lung adenocarcinomas and family members with lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Genetic variants and risk of lung cancer in never smokers: a genome-wide association study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Immunohistochemical expression of estrogen and progesterone receptors identifies a subset of NSCLCs and correlates with EGFR mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Improved survival in never-smokers vs current smokers with primary adenocarcinoma of the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Performance status and smoking status are independent favorable prognostic factors for survival in non-small cell lung cancer: a comprehensive analysis of 26,957 patients with NSCLC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Significance of Smoking as a Postoperative Prognostic Factor in Patients with Non-small Cell Lung Cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Gefitinib as a first-line therapy of advanced or metastatic adenocarcinoma of the lung in never-smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Risk factors differ for non-small-cell lung cancers with and without EGFR mutation: assessment of smoking and sex by a case-control study in Japanese

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Prognostic Implication of EGFR, KRAS, and TP53 Gene Mutations in a Large Cohort of Japanese Patients with Surgically Treated Lung Adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-011-0262-Y

Indirect estimates of lung cancer death rates in Italy not attributable to active smoking

21 January 2018

1 reference

12 December 2020

Benzo(a)pyrene diol epoxide-induced chromosomal aberrations and risk of lung cancer.

1 reference

12 December 2020

Chromosomal alterations in lung adenocarcinoma from smokers and nonsmokers

1 reference

12 December 2020

Absence of p16INK4 protein is restricted to the subset of lung cancer lines that retains wildtype RB

1 reference

12 December 2020

Smoking before surgery predicts poor long-term survival in patients with stage I non-small-cell lung carcinomas

1 reference

12 December 2020

A novel KIF5B-ALK variant in nonsmall cell lung cancer.

1 reference

12 December 2020

Gene-expression profiles predict survival of patients with lung adenocarcinoma

1 reference

12 December 2020

Survival among Chinese women with lung cancer in Singapore: a comparison by stage, histology and smoking status

1 reference

12 December 2020

HER2 mutation and response to trastuzumab therapy in non-small-cell lung cancer

1 reference

12 December 2020

Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations

1 reference

12 December 2020

Prognostic and predictive implications of HER2/ERBB2/neu gene mutations in lung cancers

1 reference

12 December 2020

Never-smokers with lung cancer: epidemiologic evidence of a distinct disease entity

1 reference

12 December 2020

Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung

1 reference

12 December 2020

Reproductive factors, hormone use and the risk of lung cancer among middle-aged never-smoking Japanese women: a large-scale population-based cohort study

1 reference

12 December 2020

p53 mutations in non-small cell lung cancer in Japan: association between mutations and smoking

1 reference

12 December 2020

Cigarette smoking and subsequent risk of lung cancer by histologic type in middle-aged Japanese men and women: The JPHC study

1 reference

12 December 2020

Trends in nonsmoking lung cancer

1 reference

12 December 2020

Chromosomal aberrations of primary lung adenocarcinomas in nonsmokers

1 reference

12 December 2020

Primary adenocarcinomas of the lung in nonsmokers show a distinct pattern of allelic imbalance.

1 reference

12 December 2020

Mutational activation of the K-ras oncogene. A possible pathogenetic factor in adenocarcinoma of the lung

1 reference

12 December 2020

Exposure to diesel motor exhaust and lung cancer risk in a pooled analysis from case-control studies in Europe and Canada

1 reference

12 December 2020

[Lung cancer in Japan: analysis of lung cancer registry cases resected in 2004]

1 reference

12 December 2020

10.1007/S10147-011-0262-Y

Identifiers

DOI

1 reference

14 September 2017

1 reference

PubMed ID

21655907