(Q39744997)

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Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20125115%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20125115%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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reactive oxygen species

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17 January 2020

9

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17 January 2020

author name string

Alberto Anel

2

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17 January 2020

Elena Catalán

3

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17 January 2020

Alvaro Sebastián

4

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17 January 2020

Rebeca Acín-Pérez

5

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17 January 2020

Javier Naval

6

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17 January 2020

Reinhard Wallich

7

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17 January 2020

Markus M Simon

8

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17 January 2020

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2 February 2010

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17 January 2020

Immunology & Cell Biology

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17 January 2020

88

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17 January 2020

5

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17 January 2020

545-554

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17 January 2020

Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Lymphocyte-mediated cytotoxicity.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Apoptosis induced by the lymphocyte effector molecule perforin

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

A proteomic approach for the discovery of protease substrates

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

The cytotoxic lymphocyte protease, granzyme B, targets the cytoskeleton and perturbs microtubule polymerization dynamics

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Identification of {alpha}-tubulin as a granzyme B substrate during CTL-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Nuclear war: the granzyme A-bomb

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Granzyme B: pro-apoptotic, antiviral and antitumor functions

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

A molecular view of cytotoxic T lymphocyte induced killing

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Granzyme B-mediated apoptosis--the elephant and the blind men?

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Cleavage of CPP32 by granzyme B represents a critical role for granzyme B in the induction of target cell DNA fragmentation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Granzyme B-induced cell death exerted by ex vivo CTL: discriminating requirements for cell death and some of its signs

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Natural killer cell-derived human granzyme H induces an alternative, caspase-independent cell-death program

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

ROS generation by nonphagocytic NADPH oxidase: potential relevance in diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

NOX enzymes and the biology of reactive oxygen

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

NADPH oxidases: not just for leukocytes anymore!

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

EGF blocks NADPH oxidase activation by TGF-beta in fetal rat hepatocytes, impairing oxidative stress, and cell death.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

mtDNA-depleted U937 cells are sensitive to TNF and Fas-mediated cytotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Role of oxidative damage and IL-1 beta-converting enzyme-like proteases in Fas-based cytotoxicity exerted by effector T cells

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Respiratory complex III is required to maintain complex I in mammalian mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Evidence that oxidative stress-induced apoptosis by menadione involves Fas-dependent and Fas-independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Targeting antioxidants to mitochondria by conjugation to lipophilic cations.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

The tyrphostin adaphostin interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Mechanisms of granule-dependent killing

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Role of NADPH oxidases in the control of vascular gene expression

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

The mitochondrial respiratory chain is a modulator of apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Cytotoxic T lymphocytes overcome Bcl-2 inhibition: target cells contribute to their own demise

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Human and murine granzyme B exhibit divergent substrate preferences

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

The major human and mouse granzymes are structurally and functionally divergent

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Alteration of the bioenergetic phenotype of mitochondria is a hallmark of breast, gastric, lung and oesophageal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Human herpesvirus 1 protein US3 induces an inhibition of mitochondrial electron transport.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Herpes simplex virus eliminates host mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Quiescent and activated mouse granulocytes do not express granzyme A and B or perforin: similarities or differences with human polymorphonuclear leukocytes?

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

Mechanism of apoptosis induced by IFN-alpha in human myeloma cells: role of Jak1 and Bim and potentiation by rapamycin.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

7 January 2021

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Requirement of caspase-3(-like) protease-mediated hydrogen peroxide production for apoptosis induced by various anticancer drugs

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

7 January 2021

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inferred from DOI database lookup

Use of polarography to detect respiration defects in cell cultures

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.5

7 January 2021

based on heuristic

inferred from DOI database lookup

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