(Q39778244)

English

Oligomerized tumor necrosis factor-related apoptosis inducing ligand strongly induces cell death in myeloma cells, but also activates proinflammatory signaling pathways

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scholarly article

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Europe PubMed Central

14 September 2017

Oligomerized tumor necrosis factor-related apoptosis inducing ligand strongly induces cell death in myeloma cells, but also activates proinflammatory signaling pathways (English)

1 reference

Europe PubMed Central

14 September 2017

apoptotic process

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9

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Europe PubMed Central

14 September 2017

Nicole Müller-Sienerth

object named as

Nicole Müller

4

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object named as

Michael Kracht

7

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1

object named as

Daniela Berg

1 reference

Europe PubMed Central

14 September 2017

author name string

Thorsten Stühmer

2

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Europe PubMed Central

14 September 2017

Daniela Siegmund

3

1 reference

Europe PubMed Central

14 September 2017

Tina Giner

5

1 reference

Europe PubMed Central

14 September 2017

Oliver Dittrich-Breiholz

6

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Europe PubMed Central

14 September 2017

Ralf Bargou

8

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Europe PubMed Central

14 September 2017

language of work or name

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publication date

6 November 2009

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Europe PubMed Central

14 September 2017

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Europe PubMed Central

14 September 2017

276

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14 September 2017

23

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14 September 2017

6912-6927

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Europe PubMed Central

14 September 2017

Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

TRAIL signals to apoptosis in chronic lymphocytic leukaemia cells primarily through TRAIL-R1 whereas cross-linked agonistic TRAIL-R2 antibodies facilitate signalling via TRAIL-R2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

The clinical trail of TRAIL.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Mcl-1L cleavage is involved in TRAIL-R1- and TRAIL-R2-mediated apoptosis induced by HGS-ETR1 and HGS-ETR2 human mAbs in myeloma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human multiple myeloma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

The proteasome inhibitor bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD)

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Death receptor-induced signaling pathways are differentially regulated by gamma interferon upstream of caspase 8 processing

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Trail induces cell migration and invasion in apoptosis-resistant cholangiocarcinoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

TRAIL regulates normal erythroid maturation through an ERK-dependent pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and TNF-alpha promote the NF-kappaB-dependent maturation of normal and leukemic myeloid cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sequentially upregulates nitric oxide and prostanoid production in primary human endothelial cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

NF-kappa B as a therapeutic target in multiple myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Interruption of the NF-kappaB pathway by Bay 11-7082 promotes UCN-01-mediated mitochondrial dysfunction and apoptosis in human multiple myeloma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Canonical nuclear factor kappaB pathway inhibition blocks myeloma cell growth and induces apoptosis in strong synergy with TRAIL.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Phosphorylation of IkappaB-alpha inhibits its cleavage by caspase CPP32 in vitro

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Apoptosis promotes a caspase-induced amino-terminal truncation of IkappaBalpha that functions as a stable inhibitor of NF-kappaB.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Non-apoptotic Fas signaling.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Role of caspases in CD95L- and TRAIL-induced non-apoptotic signalling in pancreatic tumour cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

TRAIL-induced eradication of primary tumour cells from multiple myeloma patient bone marrows is not related to TRAIL receptor expression or prior chemotherapy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Target cell-restricted and -enhanced apoptosis induction by a scFv:sTRAIL fusion protein with specificity for the pancarcinoma-associated antigen EGP2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

CD7-restricted activation of Fas-mediated apoptosis: a novel therapeutic approach for acute T-cell leukemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Cooperation between Apo2L/TRAIL and bortezomib in multiple myeloma apoptosis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Phase 1 and Pharmacokinetic Study of Lexatumumab in Patients with Advanced Cancers

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07388.X

21 January 2018

Identifiers

10.1111/J.1742-4658.2009.07388.X

1 reference

Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

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