(Q39791745)

English

Reactive oxygen species-generating mitochondrial DNA mutation up-regulates hypoxia-inducible factor-1alpha gene transcription via phosphatidylinositol 3-kinase-Akt/protein kinase C/histone deacetylase pathway

scientific article published on October 2009

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scholarly article

1 reference

Europe PubMed Central

14 September 2017

Reactive oxygen species-generating mitochondrial DNA mutation up-regulates hypoxia-inducible factor-1alpha gene transcription via phosphatidylinositol 3-kinase-Akt/protein kinase C/histone deacetylase pathway (English)

1 reference

Europe PubMed Central

14 September 2017

0 references

mitochondrial DNA

0 references

reactive oxygen species

1 reference

based on heuristic

inferred from title

author name string

Nobuko Koshikawa

1

1 reference

Europe PubMed Central

14 September 2017

Jun-Ichi Hayashi

2

1 reference

Europe PubMed Central

14 September 2017

Akira Nakagawara

3

1 reference

Europe PubMed Central

14 September 2017

Keizo Takenaga

4

1 reference

Europe PubMed Central

14 September 2017

language of work or name

0 references

publication date

1 October 2009

1 reference

Europe PubMed Central

14 September 2017

number of pages

10

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

14 September 2017

284

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Europe PubMed Central

14 September 2017

48

1 reference

Europe PubMed Central

14 September 2017

33185-33194

1 reference

Europe PubMed Central

14 September 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2785161/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury

1 reference

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Increase in gene dosage is a mechanism of HIF-1alpha constitutive expression in head and neck squamous cell carcinomas

1 reference

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A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis

1 reference

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Regulation of cancer cell metabolism by hypoxia-inducible factor 1.

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Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage.

1 reference

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Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site

1 reference

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Redox regulation of the hypoxia-inducible factor

1 reference

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The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines

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Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

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1 reference

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The human hypoxia-inducible factor 1alpha gene: HIF1A structure and evolutionary conservation

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19801684

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.054221

1 reference

Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

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