(Q39846450)

English

Cdc42 and the phosphatidylinositol 3-kinase-Akt pathway are essential for PspC-mediated internalization of pneumococci by respiratory epithelial cells

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Cdc42 and the phosphatidylinositol 3-kinase-Akt pathway are essential for PspC-mediated internalization of pneumococci by respiratory epithelial cells (English)

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

author name string

Vaibhav Agarwal

1

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Sven Hammerschmidt

2

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

language of work or name

0 references

publication date

27 May 2009

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

284

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

29

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

19427-19436

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Integrin-linked kinase is required for vitronectin-mediated internalization of Streptococcus pneumoniae by host cells

1 reference

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22 September 2017

Species-specific interaction of Streptococcus pneumoniae with human complement factor H.

1 reference

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Clostridium difficile toxins: more than mere inhibitors of Rho proteins

1 reference

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22 September 2017

Role of the small Rho GTPases Rac1 and Cdc42 in host cell invasion of Campylobacter jejuni

1 reference

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Thrombospondin-1 promotes cellular adherence of gram-positive pathogens via recognition of peptidoglycan

1 reference

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22 September 2017

Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin

1 reference

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22 September 2017

Emerging roles of pseudokinases

1 reference

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22 September 2017

Streptococcus pneumoniae induced c-Jun-N-terminal kinase- and AP-1 -dependent IL-8 release by lung epithelial BEAS-2B cells

1 reference

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22 September 2017

Adherence molecules of pathogenic pneumococci

1 reference

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22 September 2017

Clostridial Rho-inhibiting protein toxins

1 reference

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22 September 2017

Bacterial virulence strategies that utilize Rho GTPases

1 reference

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22 September 2017

The phosphoinositide 3-kinase pathway and cancer

1 reference

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22 September 2017

The phosphoinositol-3-kinase-protein kinase B/Akt pathway is critical for Pseudomonas aeruginosa strain PAK internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Solution structure of choline binding protein A, the major adhesin of Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Pathogen-induced actin filament rearrangement in infectious diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Large clostridial cytotoxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Activation of endogenous Cdc42 visualized in living cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Bacterial invasion: the paradigms of enteroinvasive pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Ectodomains 3 and 4 of human polymeric Immunoglobulin receptor (hpIgR) mediate invasion of Streptococcus pneumoniae into the epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

M1 protein triggers a phosphoinositide cascade for group A Streptococcus invasion of epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

The human polymeric immunoglobulin receptor binds to Streptococcus pneumoniae via domains 3 and 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Unravelling the activation mechanisms of protein kinase B/Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Immunoglobulin transport across polarized epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Identification of MEK- and phosphoinositide 3-kinase-dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Pneumococcal disease in western Europe: burden of disease, antibiotic resistance and management

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

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Specific entry of Helicobacter pylori into cultured gastric epithelial cells via a zipper-like mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Cdc42-dependent modulation of tight junctions and membrane protein traffic in polarized Madin-Darby canine kidney cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Polymeric IgA binding to the human pIgR elicits intracellular signalling, but fails to stimulate pIgR-transcytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Accumulation of GTP-bound RhoA during cytokinesis and a critical role of ECT2 in this accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Selective alterations in biosynthetic and endocytic protein traffic in Madin-Darby canine kidney epithelial cells expressing mutants of the small GTPase Rac1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Modulation of endocytic traffic in polarized Madin-Darby canine kidney cells by the small GTPase RhoA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Transduction of basolateral-to-apical signals across epithelial cells: ligand-stimulated transcytosis of the polymeric immunoglobulin receptor requires two signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases

1 reference

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22 September 2017

Rho GTPases control polarity, protrusion, and adhesion during cell movement

1 reference

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22 September 2017

Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases

1 reference

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22 September 2017

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1 reference

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Role of tyrosine phosphorylation in ligand-induced regulation of transcytosis of the polymeric Ig receptor

1 reference

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S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells.

1 reference

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1 reference

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1 reference

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Epithelial cell polarization is a determinant in the infectious outcome of immunoglobulin A-mediated entry by Epstein-Barr virus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Signal transduction by the polymeric immunoglobulin receptor suggests a role in regulation of receptor transcytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Stimulation of transcytosis of the polymeric immunoglobulin receptor by dimeric IgA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

22 September 2017

Mycobacterium avium enters intestinal epithelial cells through the apical membrane, but not by the basolateral surface, activates small GTPase Rho and, once within epithelial cells, expresses an invasive phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

25 September 2017

Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

25 September 2017

The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

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A role for phosphoinositide 3-kinase in bacterial invasion

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25 September 2017

Comparative studies of transcytosis and assembly of secretory IgA in Madin-Darby canine kidney cells expressing human polymeric Ig receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

25 September 2017

Wortmannin, an inhibitor of phosphoinositide 3-kinase, inhibits transcytosis in polarized epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

25 September 2017

Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

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The SRC family protein tyrosine kinase p62yes controls polymeric IgA transcytosis in vivo

1 reference

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17 June 2018

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1 reference

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17 June 2018

Immunoglobulin A-Induced Shift of Epstein-Barr Virus Tissue Tropism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

17 June 2018

Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

20 August 2018

Dual roles of PspC, a surface protein of Streptococcus pneumoniae, in binding human secretory IgA and factor H.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

20 August 2018

Rho GTPase activity modulates Pseudomonas aeruginosa internalization by epithelial cells.

1 reference

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20 August 2018

Species-specific binding of human secretory component to SpsA protein of Streptococcus pneumoniae via a hexapeptide motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

20 August 2018

IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740568

20 August 2018

Rac1, RhoA, and Cdc42 participate in HeLa cell invasion by group B streptococcus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.003442

21 January 2018

Both microtubules and actin filaments are required for efficient postendocytotic traffic of the polymeric immunoglobulin receptor in polarized Madin-Darby canine kidney cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19473971

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streptococcus pneumoniae recruits complement factor H through the amino terminus of CbpA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19473971

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large scale synthesis of the Cdc42 inhibitor secramine A and its inhibition of cell spreading

1 reference

https://pubmed.ncbi.nlm.nih.gov/19473971

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The host immune regulator factor H interacts via two contact sites with the PspC protein of Streptococcus pneumoniae and mediates adhesion to host epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19473971

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho proteins and the p38-MAPK pathway are important mediators for LPS-induced interleukin-8 expression in human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19473971

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase activation and interaction with focal adhesion kinase in Escherichia coli K1 invasion of human brain microvascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19473971

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.003442

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

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