(Q39847607)

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DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis

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scholarly article

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Europe PubMed Central

PubMed publication ID

15 September 2017

DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis (English)

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Europe PubMed Central

PubMed publication ID

15 September 2017

whole genome sequencing

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based on heuristic

inferred from title

Zita A. Sibenaller

5

object named as

Z Sibenaller

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Europe PubMed Central

PubMed publication ID

15 September 2017

author name string

G Foltz

1

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Europe PubMed Central

PubMed publication ID

15 September 2017

J-G Yoon

2

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Europe PubMed Central

PubMed publication ID

15 September 2017

H Lee

3

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

T C Ryken

4

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

M Ehrich

6

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

L Hood

7

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Europe PubMed Central

PubMed publication ID

15 September 2017

A Madan

8

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Europe PubMed Central

PubMed publication ID

15 September 2017

language of work or name

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publication date

25 May 2009

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Europe PubMed Central

PubMed publication ID

15 September 2017

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Europe PubMed Central

PubMed publication ID

15 September 2017

28

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Europe PubMed Central

PubMed publication ID

15 September 2017

29

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

2667-2677

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Europe PubMed Central

PubMed publication ID

15 September 2017

https://scigraph.springernature.com/pub.10.1038/onc.2009.122

0 references

Molecular genetic analysis of BAX and cyclin D1 genes in patients with malignant glioma

1 reference

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DNA methylation in ovarian cancer. II. Expression of DNA methyltransferases in ovarian cancer cell lines and normal ovarian epithelial cells

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Regional DNA hypermethylation and DNA methyltransferase (DNMT) 1 protein overexpression in both renal tumors and corresponding nontumorous renal tissues.

1 reference

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DNA methylation and gene silencing in cancer

1 reference

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Primary brain tumours in adults.

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CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles

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Cancer genes hypermethylated in human embryonic stem cells

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Distinct sets of genetic alterations in melanoma

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The genome and epigenome of malignant melanoma

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N-Myc downstream-regulated gene 2 (NDRG2) inhibits glioblastoma cell proliferation

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Tumor suppressor gene promoter hypermethylation in serum of breast cancer patients.

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Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

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Cytosine methylation profiling of cancer cell lines.

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Expression of Dnmt1, demethylase, MeCP2 and methylation of tumor-related genes in human gastric cancer

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Syndecan-2 is expressed in the microvasculature of gliomas and regulates angiogenic processes in microvascular endothelial cells

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Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma

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O6-methylguanine-DNA-methyltransferase promoter demethylation is involved in basic fibroblast growth factor induced resistance against temozolomide in human melanoma cells

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Consed: a graphical tool for sequence finishing

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Epigenetic changes in cancer

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Radiation resistance and stem-like cells in brain tumors.

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New insights into syndecan-2 expression and tumourigenic activity in colon carcinoma cells

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High-resolution mapping of DNA methylation in human genome using oligonucleotide tiling array

1 reference

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MGMT gene silencing and benefit from temozolomide in glioblastoma

1 reference

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Tumor Cell-SpecificBRCA1andRASSF1AHypermethylation in Serum, Plasma, and Peritoneal Fluid from Ovarian Cancer Patients

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Epigenetic regulation of X-linked cancer/germline antigen genes by DNMT1 and DNMT3b

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Elevated mRNA levels of DNA methyltransferase-1 as an independent prognostic factor in primary nonsmall cell lung cancer.

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Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma.

1 reference

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Decreased syndecan-2 expression correlates with trichostatin-A induced-morphological changes and reduced tumorigenic activity in colon carcinoma cells

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Cooperation of syndecan-2 and syndecan-4 among cell surface heparan sulfate proteoglycans in the actin cytoskeletal organization of Lewis lung carcinoma cells

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CpG island promoter hypermethylation of the pro-apoptotic gene caspase-8 is a common hallmark of relapsed glioblastoma multiforme.

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Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state

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Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

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DNA methyltransferase 1 knock down induces gene expression by a mechanism independent of DNA methylation and histone deacetylation

1 reference

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DNA methylation: the nuts and bolts of repression

1 reference

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Identification of molecular subtypes of glioblastoma by gene expression profiling.

1 reference

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Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia

1 reference

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Syndecan-2 overexpression induces osteosarcoma cell apoptosis: Implication of syndecan-2 cytoplasmic domain and JNK signaling.

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Downregulation of RUNX3 and TES by hypermethylation in glioblastoma

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Syndecan-2 mediates adhesion and proliferation of colon carcinoma cells.

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DNA methyltransferase expression and DNA hypermethylation in human hepatocellular carcinoma.

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Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases

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Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

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Chromatin remodeling, measured by a novel real-time polymerase chain reaction assay, across the proximal promoter region of the IL-2 gene.

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DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

1 reference

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DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

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p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis.

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Comparing the DNA hypermethylome with gene mutations in human colorectal cancer

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Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression

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Downregulation of putative tumor suppressor gene TSC-22 in human brain tumors

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Identification of human brain tumour initiating cells

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Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma

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RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells

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The adenocarcinoma-associated antigen, AGR2, promotes tumor growth, cell migration, and cellular transformation

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Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines.

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DNA stool test for colorectal cancer: hypermethylation of the secreted frizzled-related protein-1 gene.

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Inactivation of tumor suppressor genes: choice between genetic and epigenetic routes

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DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers.

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The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14(ARF), p16(INK4a) and RASSF1A in human lung cancer cell lines

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Identifiers

10.1038/ONC.2009.122

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

ResearchGate publication ID

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