(Q39881883)

15 September 2017

Pifithrin-alpha protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53. (English)

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15 September 2017

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D Sohn

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15 September 2017

V Graupner

2

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15 September 2017

D Neise

3

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15 September 2017

F Essmann

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15 September 2017

K Schulze-Osthoff

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15 September 2017

R U Jänicke

6

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15 September 2017

20 February 2009

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Cell Death & Differentiation

15 September 2017

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15 September 2017

16

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15 September 2017

6

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15 September 2017

869-878

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https://scigraph.springernature.com/pub.10.1038/cdd.2009.17

15 September 2017

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7 January 2021

Effect of mutated TP53 on response of advanced breast cancers to high-dose chemotherapy

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The role of p53 in determining sensitivity to radiotherapy

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A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

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7 January 2021

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

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7 January 2021

Inhibition of p53 protects liver tissue against endotoxin-induced apoptotic and necrotic cell death

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7 January 2021

The role of p53-induced apoptosis in cerebral ischemia: effects of the p53 inhibitor pifithrin alpha

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7 January 2021

Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells

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7 January 2021

An evaluation of the ability of pifithrin-alpha and -beta to inhibit p53 function in two wild-type p53 human tumor cell lines

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7 January 2021

Regulation of p53 and suppression of apoptosis by the soluble guanylyl cyclase/cGMP pathway in human ovarian cancer cells.

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7 January 2021

Involvement of p53 in specific anti-neuroectodermal tumor activity of aloe-emodin

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7 January 2021

The p53 inhibitor pifithrin-alpha is a potent agonist of the aryl hydrocarbon receptor

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7 January 2021

p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways.

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7 January 2021

Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation.

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7 January 2021

p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activation

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7 January 2021

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

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7 January 2021

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

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7 January 2021

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

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7 January 2021

Mitochondria and apoptosis

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https://api.crossref.org/works/10.1038%2FCDD.2009.17

7 January 2021

Caspase-9 can be activated without proteolytic processing

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https://api.crossref.org/works/10.1038%2FCDD.2009.17

7 January 2021

The apoptosome activates caspase-9 by dimerization

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7 January 2021

Coordinated regulation of life and death by RB.

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7 January 2021

The multiple battles fought by anti-apoptotic p21.

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7 January 2021

Inhibition of p53 response in tumor stroma improves efficacy of anticancer treatment by increasing antiangiogenic effects of chemotherapy and radiotherapy in mice

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7 January 2021

The dark side of a tumor suppressor: anti-apoptotic p53.

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7 January 2021

Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide

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7 January 2021

Inhibition of p73 function by Pifithrin-alpha as revealed by studies in zebrafish embryos

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7 January 2021

p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation

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7 January 2021

Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis

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7 January 2021

Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons

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https://api.crossref.org/works/10.1038%2FCDD.2009.17

7 January 2021

Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis

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7 January 2021

Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: class differences and the potential influence of p53.

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7 January 2021

Pifithrin-alpha, an inhibitor of p53, enhances the genetic instability induced by etoposide (VP16) in human lymphoblastoid cells treated in vitro

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7 January 2021

atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity

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https://api.crossref.org/works/10.1038%2FCDD.2009.17

7 January 2021

Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

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https://api.crossref.org/works/10.1038%2FCDD.2009.17

7 January 2021

A unique pattern of photoreceptor degeneration in cyclin D1 mutant mice

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https://api.crossref.org/works/10.1038%2FCDD.2009.17

7 January 2021

Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.17

7 January 2021

Living with or without cyclins and cyclin-dependent kinases

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https://api.crossref.org/works/10.1038%2FCDD.2009.17

7 January 2021

Minireview: Cyclin D1: normal and abnormal functions

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https://api.crossref.org/works/10.1038%2FCDD.2009.17

7 January 2021

Irradiation-induced translocation of p53 to mitochondria in the absence of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.17

7 January 2021

Apoptosis resistance of MCF-7 breast carcinoma cells to ionizing radiation is independent of p53 and cell cycle control but caused by the lack of caspase-3 and a caffeine-inhibitable event

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.17

7 January 2021

Caspase-8 can be activated by interchain proteolysis without receptor-triggered dimerization during drug-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.17

7 January 2021

Identifiers

DOI

10.1038/CDD.2009.17

1 reference

15 September 2017

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