(Q39894500)

15 September 2017

title

Regulation of heat-induced apoptosis by Mcl-1 degradation and its inhibition by Hsp70. (English)

1 reference

15 September 2017

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A R Stankiewicz

1

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15 September 2017

A M Livingstone

series ordinal

2

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15 September 2017

N Mohseni

series ordinal

3

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15 September 2017

D D Mosser

series ordinal

4

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15 September 2017

language of work or name

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16 January 2009

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Cell Death & Differentiation

15 September 2017

published in

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15 September 2017

volume

16

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15 September 2017

issue

4

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15 September 2017

page(s)

638-647

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https://scigraph.springernature.com/pub.10.1038/cdd.2008.189

15 September 2017

exact match

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cites work

Apoptosis: controlled demolition at the cellular level

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2008.189

The Bcl-2 apoptotic switch in cancer development and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

The multidomain proapoptotic molecules Bax and Bak are directly activated by heat

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Structural insights into the degradation of Mcl-1 induced by BH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

BH3-ligand regulates access of MCL-1 to its E3 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Induced thermotolerance to apoptosis in a human T lymphocyte cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

The chaperone function of hsp70 is required for protection against stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Characterisation of Mcl-1 cleavage during apoptosis of haematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Cooperation of molecular chaperones with the ubiquitin/proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Molecular chaperones and the stress of oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Regulating the regulators: control of protein ubiquitination and ubiquitin-like modifications by extracellular stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

A pivotal role for Mcl-1 in Bortezomib-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Acute acidification or amiloride treatment suppresses the ability of Hsp70 to inhibit heat-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

Unraveling MCL-1 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

inferred from DOI database lookup

7 January 2021

based on heuristic

Functional linkage between NOXA and Bim in mitochondrial apoptotic events

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

inferred from DOI database lookup

7 January 2021

based on heuristic

Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotolerance

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.189

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/CDD.2008.189

1 reference

15 September 2017

1 reference