(Q39909069)

15 September 2017

Human CDT1 associates with CDC7 and recruits CDC45 to chromatin during S phase (English)

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15 September 2017

7

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15 September 2017

Andrea Ballabeni

1

1 reference

15 September 2017

Raffaella Zamponi

2

1 reference

15 September 2017

Greta Caprara

3

1 reference

15 September 2017

Marina Melixetian

4

1 reference

15 September 2017

Sergio Bossi

5

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15 September 2017

Laura Masiero

6

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15 September 2017

language of work or name

English

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publication date

3 December 2008

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Journal of Biological Chemistry

15 September 2017

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15 September 2017

284

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15 September 2017

5

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15 September 2017

3028-3036

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The Cdc7 protein kinase is required for origin firing during S phase

15 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Cdc7 is required throughout the yeast S phase to activate replication origins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

DNA replication in eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

The Cdt1 protein is required to license DNA for replication in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Evidence for sequential action of cdc7 and cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Hierarchy of S-phase-promoting factors: yeast Dbf4-Cdc7 kinase requires prior S-phase cyclin-dependent kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

CDC45 is required in conjunction with CDC7/DBF4 to trigger the initiation of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

CDC45, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Interaction of Dbf4, the Cdc7 protein kinase regulatory subunit, with yeast replication origins in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

A role for the Cdc7 kinase regulatory subunit Dbf4p in the formation of initiation-competent origins of replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

CELLULAR DNA REPLICASES: Components and Dynamics at the Replication Fork

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Right place, right time, and only once: replication initiation in metazoans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Regulation of early events in chromosome replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Loss of Geminin induces rereplication in the presence of functional p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Control of DNA replication and chromosome ploidy by geminin and cyclin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Control of DNA replication: regulation and activation of eukaryotic replicative helicase, MCM

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

DNA unwinding is an Mcm complex-dependent and ATP hydrolysis-dependent process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Rapid degradation of Cdt1 upon UV-induced DNA damage is mediated by SCFSkp2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

An evolutionarily conserved function of proliferating cell nuclear antigen for Cdt1 degradation by the Cul4-Ddb1 ubiquitin ligase in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Cell cycle regulation of the licensing activity of Cdt1 in Xenopus laevis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

The replicative regulator protein geminin on chromatin in the HeLa cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Functional domains of the Xenopus replication licensing factor Cdt1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Structural basis for inhibition of the replication licensing factor Cdt1 by geminin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Geminin-Cdt1 balance is critical for genetic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

Degradation of Cdt1 during S phase is Skp2-independent and is required for efficient progression of mammalian cells through S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803609200

21 January 2018

Identifiers

DOI

10.1074/JBC.M803609200

1 reference

15 September 2017

1 reference