(Q40563928)

21 September 2017

Rapid degradation of Cdt1 upon UV-induced DNA damage is mediated by SCFSkp2 complex (English)

1 reference

21 September 2017

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Takeshi Kondo

1

1 reference

21 September 2017

Masanobu Kobayashi

2

1 reference

21 September 2017

Junko Tanaka

3

1 reference

21 September 2017

Akiko Yokoyama

4

1 reference

21 September 2017

Sachiko Suzuki

5

1 reference

21 September 2017

Naoko Kato

6

1 reference

21 September 2017

Masahiro Onozawa

7

1 reference

21 September 2017

Kohji Chiba

8

1 reference

21 September 2017

Satoshi Hashino

9

1 reference

21 September 2017

Masahiro Imamura

10

1 reference

21 September 2017

Yasuhiro Minami

11

1 reference

21 September 2017

Naoto Minamino

12

1 reference

21 September 2017

Masahiro Asaka

13

1 reference

21 September 2017

language of work or name

English

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publication date

20 April 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

26

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21 September 2017

27315-27319

1 reference

XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

The Cdt1 protein is required to license DNA for replication in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

Geminin, an inhibitor of DNA replication, is degraded during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

Control of DNA replication and chromosome ploidy by geminin and cyclin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

ATM and ATR: networking cellular responses to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

The DNA damage response: putting checkpoints in perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

Transcriptional activation by tetracyclines in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

The F-box protein SKP2 binds to the phosphorylated threonine 380 in cyclin E and regulates ubiquitin-dependent degradation of cyclin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

UV irradiation triggers ubiquitin-dependent degradation of p21(WAF1) to promote DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

Oncogenic potential of the DNA replication licensing protein CDT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314023200

21 January 2018

Identifiers

DOI

10.1074/JBC.M314023200

1 reference

21 September 2017

1 reference