(Q39943823)

English

The extreme COOH terminus of the retinoblastoma tumor suppressor protein pRb is required for phosphorylation on Thr-373 and activation of E2F.

scientific article published on 3 September 2008

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

The extreme COOH terminus of the retinoblastoma tumor suppressor protein pRb is required for phosphorylation on Thr-373 and activation of E2F. (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

phosphorylation

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Laura L Gorges

1

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Nathan H Lents

2

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Joseph J Baldassare

3

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

publication date

3 September 2008

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

American Journal of Physiology - Cell Physiology

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

295

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

C1151-60

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activation

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Retinoblastoma protein recruits histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

The E2F transcription factor is a cellular target for the RB protein

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Physical interaction of the retinoblastoma protein with human D cyclins

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Differential regulation of E2F transactivation by cyclin/cdk2 complexes

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Specific regulation of E2F family members by cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

The regulation of E2F by pRB-family proteins

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

A novel role for Gq alpha in alpha-thrombin-mediated mitogenic signalling pathways

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

The oncogenic activity of cyclin E is not confined to Cdk2 activation alone but relies on several other, distinct functions of the protein

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Cyclin E, a redundant cyclin in breast cancer

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Rb function in cell-cycle regulation and apoptosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Crystal Structure of the Retinoblastoma Protein N Domain Provides Insight into Tumor Suppression, Ligand Interaction, and Holoprotein Architecture

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Molecular mechanisms of oncogenic mutations in tumors from patients with bilateral and unilateral retinoblastoma

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Expression of cyclin E renders cyclin D-CDK4 dispensable for inactivation of the retinoblastoma tumor suppressor protein, activation of E2F, and G1-S phase progression

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Redundant cyclin overexpression and gene amplification in breast cancer cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Cyclin E and survival in patients with breast cancer

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Concurrent amplification of cyclin E and CDK2 genes in colorectal carcinomas

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Cyclin A is a functional target of retinoblastoma tumor suppressor protein-mediated cell cycle arrest

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Inactivation of the retinoblastoma susceptibility gene in human breast cancers

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Human retinoblastoma susceptibility gene: cloning, identification, and sequence

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Reverse mutational analysis reveals threonine-373 as a potentially sufficient phosphorylation site for inactivation of the retinoblastoma tumor suppressor protein (pRB).

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Rb interacts with histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Rb targets histone H3 methylation and HP1 to promoters

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Regulation of the cyclin E gene by transcription factor E2F1

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Identification of a growth suppression domain within the retinoblastoma gene product

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Differential prognostic impact of the cyclins E and B in premenopausal and postmenopausal women with lymph node-negative breast cancer

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

The RB and p53 pathways in cancer

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Cyclin-E is a strong predictor of endocrine therapy failure in human breast cancer.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Restoration of retinoblastoma mediated signaling to Cdk2 results in cell cycle arrest

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

BRG-1 is required for RB-mediated cell cycle arrest

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Oncogenic point mutations in the human retinoblastoma gene: their application to genetic counseling

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Further characterization of retinoblastoma gene-mediated cell growth and tumor suppression in human cancer cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Cyclin E is a more powerful predictor of breast cancer outcome than proliferation

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00300.2008

21 January 2018

Identifiers

10.1152/AJPCELL.00300.2008

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

ResearchGate publication ID

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