(Q39948282)

English

A proposal for a pharmacokinetic interaction significance classification system (PISCS) based on predicted drug exposure changes and its potential application to alert classifications in product labelling

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

A proposal for a pharmacokinetic interaction significance classification system (PISCS) based on predicted drug exposure changes and its potential application to alert classifications in product labelling (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Akihiro Hisaka

1

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Makiko Kusama

2

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Yoshiyuki Ohno

3

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Yuichi Sugiyama

4

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Hiroshi Suzuki

5

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 January 2009

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Clinical Pharmacokinetics

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

48

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

653-666

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

https://scigraph.springernature.com/pub.10.2165/11317220-000000000-00000

0 references

Food-drug interactions via human cytochrome P450 3A (CYP3A).

1 reference

https://api.crossref.org/works/10.2165%2F11317220-000000000-00000

21 January 2018

Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole

1 reference

https://api.crossref.org/works/10.2165%2F11317220-000000000-00000

21 January 2018

Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole.

1 reference

https://api.crossref.org/works/10.2165%2F11317220-000000000-00000

21 January 2018

A potentially hazardous interaction between erythromycin and midazolam.

1 reference

https://api.crossref.org/works/10.2165%2F11317220-000000000-00000

21 January 2018

Dose of midazolam should be reduced during diltiazem and verapamil treatments

1 reference

https://api.crossref.org/works/10.2165%2F11317220-000000000-00000

21 January 2018

Cimetidine and ranitidine increase midazolam bioavailability.

1 reference

https://api.crossref.org/works/10.2165%2F11317220-000000000-00000

21 January 2018

Ranitidine influences the uptake of oral midazolam

1 reference

https://api.crossref.org/works/10.2165%2F11317220-000000000-00000

21 January 2018

Comparative pharmacodynamics of eight calcium channel blocking agents in Japanese essential hypertensive patients

1 reference

https://api.crossref.org/works/10.2165%2F11317220-000000000-00000

21 January 2018

Is there a rationale for prescription of benzodiazepines in the elderly? Review of the literature

1 reference

https://api.crossref.org/works/10.2165%2F11317220-000000000-00000

21 January 2018

Dose dependent effect of diltiazem on the pharmacokinetics of nifedipine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minimizing polymorphic metabolism in drug discovery: evaluation of the utility of in vitro methods for predicting pharmacokinetic consequences associated with CYP2D6 metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism-based inactivation of human cytochrome P450 enzymes: strategies for diagnosis and drug-drug interaction risk assessment

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methods for predicting in vivo pharmacokinetics using data from in vitro assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Itraconazole alters the pharmacokinetics of atorvastatin to a greater extent than either cerivastatin or pravastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interaction of diltiazem with simvastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospective study of the safety and financial benefit of ketoconazole as adjunctive therapy to cyclosporine after heart transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and hemodynamic effects of nisoldipine and its interaction with cimetidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

General framework for the prediction of oral drug interactions caused by CYP3A4 induction from in vivo information

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of parallel pathways of drug elimination and multiple cytochrome P450 involvement on drug-drug interactions: CYP2D6 paradigm.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of in vivo drug-drug interactions from in vitro data : factors affecting prototypic drug-drug interactions involving CYP2C9, CYP2D6 and CYP3A4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of the systemic antimycotics, itraconazole and fluconazole, on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic and Pharmacodynamic Interactions of Oral Midazolam with Ketoconazole, Fluoxetine, Fluvoxamine, and Nefazodone

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between cyclosporin and lipid-lowering drugs: implications for organ transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of midazolam and simvastatin as cytochrome P450 3A probes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent cytochrome P450 2C19 genotype–related interaction between voriconazole and the cytochrome P450 3A4 inhibitor ritonavir

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voriconazole and sirolimus coadministration after allogeneic hematopoietic stem cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of the antibiotics erythromycin and azithromycin on the pharmacokinetics and pharmacodynamics of midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of ketoconazole on the pharmacokinetics, pharmacodynamics and safety of nisoldipine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A significant drug-metabolizing role for CYP3A5?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of in vivo drug-drug interactions from in vitro data: impact of incorporating parallel pathways of drug elimination and inhibitor absorption rate constant

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: effect of ketoconazole.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steady-state pharmacokinetic and safety profiles of voriconazole and ritonavir in healthy male subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of itraconazole on the single oral dose pharmacokinetics and pharmacodynamics of alprazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma buspirone concentrations are greatly increased by erythromycin and itraconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Withdrawal of cerivastatin from the world market

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between midazolam and clarithromycin: comparison with azithromycin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of itraconazole on the pharmacokinetics of atorvastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of CYP3A4 in vitro data to predict clinical drug-drug interactions; predictions of compounds as objects of interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pharmacokinetic interaction between roxithromycin and midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ketoconazole inhibition of triazolam and alprazolam clearance: differential kinetic and dynamic consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Azithromycin does not increase plasma concentrations of oral midazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential time-dependent inactivation of P450 3A4 and P450 3A5 by raloxifene: a key role for C239 in quenching reactive intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human hepatic cytochromes P450 involved in drug metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P-450 3A4: regulation and role in drug metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

General framework for the quantitative prediction of CYP3A4-mediated oral drug interactions based on the AUC increase by coadministration of standard drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Database analyses for the prediction of in vivo drug-drug interactions from in vitro data

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification of the pharmacokinetics of cyclosporine A and metabolites by the concomitant use of Neoral and diltiazem or ketoconazol in stable adult kidney transplants

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of voriconazole on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of H2 receptor antagonists on the plasma concentrations of midazolam and temazepam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-related effect of triazolam on postural sway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of CYP3A5 expression on the extent of hepatic CYP3A inhibition is substrate-dependent: an in vitro-in vivo evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in the inhibition of cytochromes P450 3A4 and 3A5 by metabolite-inhibitor complex-forming drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voriconazole: therapeutic review of a new azole antifungal

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of pharmacogenomics in clinical pharmacology

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The utility of in vitro cytochrome P450 inhibition data in the prediction of drug-drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

H1-receptor antagonists: safety issues

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predicting in vivo drug interactions from in vitro drug discovery data

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trends in new drug interactions for pharmaceutical products in Japan

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drugs as CYP3A probes, inducers, and inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

XIST repression in the absence of DNMT1 and DNMT3B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic and dynamic interaction study of zolpidem with ketoconazole, itraconazole, and fluconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of the minor cytochrome P450 3A isoforms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of buspirone with itraconazole and rifampicin: effects on the pharmacokinetics of the active 1-(2-pyrimidinyl)-piperazine metabolite of buspirone

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Itraconazole greatly increases plasma concentrations and effects of felodipine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linear relationship between GABAA receptor occupancy of muscimol and glucose metabolic response in the conscious mouse brain. Clinical implication based on comparison with benzodiazepine receptor agonist.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rational use of benzodiazepines in the elderly

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different effects of itraconazole on the pharmacokinetics of fluvastatin and lovastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statin-associated myopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of antifungal drugs on cytochrome P450 (CYP) 2C9, CYP2C19, and CYP3A4 activities in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Open-label, nonrandomized study of the effects of gatifloxacin on the pharmacokinetics of midazolam in healthy male volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statin safety and drug interactions: clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/19743887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/11317220-000000000-00000

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

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