(Q45041991)

8 December 2017

title

General framework for the prediction of oral drug interactions caused by CYP3A4 induction from in vivo information (English)

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8 December 2017

Yoshiyuki Ohno

1

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8 December 2017

Akihiro Hisaka

series ordinal

2

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8 December 2017

Masaki Ueno

series ordinal

3

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8 December 2017

Hiroshi Suzuki

series ordinal

4

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8 December 2017

publication date

1 January 2008

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Clinical Pharmacokinetics

8 December 2017

published in

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8 December 2017

volume

47

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8 December 2017

issue

10

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8 December 2017

page(s)

669-680

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https://scigraph.springernature.com/pub.10.2165/00003088-200847100-00004

8 December 2017

exact match

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cites work

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Hyperforin content determines the magnitude of the St John's wort-cyclosporine drug interaction.

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Induction of the metabolism of etizolam by carbamazepine in humans

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The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

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The effect of carbamazepine on the steady-state pharmacokinetics of ziprasidone in healthy volunteers

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12 December 2020

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12 December 2020

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12 December 2020

Effect of itraconazole on the pharmacokinetics of prednisolone and methylprednisolone and cortisol secretion in healthy subjects

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12 December 2020

General framework for the quantitative prediction of CYP3A4-mediated oral drug interactions based on the AUC increase by coadministration of standard drugs

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Rifampicin reduces effectiveness and bioavailability of prednisolone.

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12 December 2020

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12 December 2020

Prediction of midazolam-CYP3A inhibitors interaction in the human liver from in vivo/in vitro absorption, distribution, and metabolism data.

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12 December 2020

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

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12 December 2020

Inhibition and induction of cytochrome P450 and the clinical implications

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12 December 2020

Influence of rifampicin on the expression and function of human intestinal cytochrome P450 enzymes

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12 December 2020

Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction

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12 December 2020

The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity

1 reference

12 December 2020

The effect of fluconazole on circulating ethinyl estradiol levels in women taking oral contraceptives

1 reference

12 December 2020

Alterations in cyclosporin A pharmacokinetics and metabolism during treatment with St John's wort in renal transplant patients

1 reference

12 December 2020

Pharmacokinetic interaction between ketoconazole and imatinib mesylate (Glivec) in healthy subjects

1 reference

12 December 2020

Effects of carbamazepine on cyclosporine metabolism in pediatric renal transplant recipients

1 reference

12 December 2020

The nifedipine-rifampin interaction. Evidence for induction of gut wall metabolism

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12 December 2020

Renal hemodynamics and pharmacokinetics of bosentan with and without cyclosporine A

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12 December 2020

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

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12 December 2020

Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine

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12 December 2020

Pharmacokinetic drug interactions involving 17alpha-ethinylestradiol: a new look at an old drug

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12 December 2020

Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction

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12 December 2020

Induction and drug development

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12 December 2020

Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism.

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12 December 2020

Effect of St John's wort on drug metabolism by induction of cytochrome P450 3A4 enzyme

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12 December 2020

Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics

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12 December 2020

Pharmacokinetic drug interactions of gefitinib with rifampicin, itraconazole and metoprolol

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12 December 2020

Carbamazepine markedly reduces serum concentrations of simvastatin and simvastatin acid

1 reference

12 December 2020

Evaluation of cyclosporin-phenytoin interaction with observations on cyclosporin metabolites

1 reference

12 December 2020

Prediction of time-dependent CYP3A4 drug-drug interactions: impact of enzyme degradation, parallel elimination pathways, and intestinal inhibition

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12 December 2020

Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction

1 reference

12 December 2020

Effect of itraconazole on the pharmacokinetics and pharmacodynamics of zopiclone

1 reference

12 December 2020

Cytochrome P450 3A expression and activity in the human small intestine

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12 December 2020

Decreased plasma levels of amitriptyline and its metabolites on comedication with an extract from St. John's wort ( Hypericum perforatum ).

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12 December 2020

Interactions of buspirone with itraconazole and rifampicin: effects on the pharmacokinetics of the active 1-(2-pyrimidinyl)-piperazine metabolite of buspirone

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12 December 2020

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

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12 December 2020

Five distinct human cytochromes mediate amitriptyline N-demethylation in vitro: dominance of CYP 2C19 and 3A4

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12 December 2020

Rifampin greatly reduces plasma simvastatin and simvastatin acid concentrations

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12 December 2020

Update: clinically significant cytochrome P-450 drug interactions

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12 December 2020

Effects of the antifungal agents on oxidative drug metabolism: clinical relevance

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12 December 2020

Mechanism-based inactivation of CYP3A by HIV protease inhibitors

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12 December 2020

Rifampin drastically reduces plasma concentrations and effects of oral midazolam.

1 reference

12 December 2020

Prediction of in vivo drug-drug interactions based on mechanism-based inhibition from in vitro data: inhibition of 5-fluorouracil metabolism by (E)-5-(2-Bromovinyl)uracil

1 reference

12 December 2020

The effect of itraconazole on the pharmacokinetics and pharmacodynamics of oral prednisolone

1 reference

12 December 2020

10.2165/00003088-200847100-00004

Identifiers

DOI

1 reference

Dimensions Publication ID

8 December 2017

1032351204

0 references

1 reference