(Q34656231)

English

General framework for the quantitative prediction of CYP3A4-mediated oral drug interactions based on the AUC increase by coadministration of standard drugs

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

General framework for the quantitative prediction of CYP3A4-mediated oral drug interactions based on the AUC increase by coadministration of standard drugs (English)

1 reference

Europe PubMed Central

3 August 2017

author name string

Yoshiyuki Ohno

1

1 reference

Europe PubMed Central

3 August 2017

Akihiro Hisaka

2

1 reference

Europe PubMed Central

3 August 2017

Hiroshi Suzuki

3

1 reference

Europe PubMed Central

3 August 2017

publication date

1 January 2007

1 reference

Europe PubMed Central

3 August 2017

Clinical Pharmacokinetics

1 reference

Europe PubMed Central

3 August 2017

46

1 reference

Europe PubMed Central

3 August 2017

681-696

1 reference

Europe PubMed Central

3 August 2017

8

1 reference

Europe PubMed Central

3 August 2017

https://scigraph.springernature.com/pub.10.2165/00003088-200746080-00005

0 references

Human jejunal effective permeability and its correlation with preclinical drug absorption models

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200746080-00005

21 January 2018

The pharmacokinetics and pharmacodynamics of nifedipine at steady state during concomitant administration of cimetidine or high dose ranitidine

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200746080-00005

21 January 2018

Triazolam Kinetics: Interaction with Cimetidine, Propranolol, and the Combination

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200746080-00005

21 January 2018

Dose of midazolam should be reduced during diltiazem and verapamil treatments

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200746080-00005

21 January 2018

Cyclosporin-erythromycin interaction in renal transplant patients

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200746080-00005

21 January 2018

Ranitidine influences the uptake of oral midazolam

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200746080-00005

21 January 2018

Models of hepatic drug clearance: discrimination between the ‘well stirred’ and ‘parallel-tube’ models

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200746080-00005

21 January 2018

How useful is the "cocktail approach" for evaluating human hepatic drug metabolizing capacity using cytochrome P450 phenotyping probes in vivo?

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200746080-00005

21 January 2018

Dose dependent effect of diltiazem on the pharmacokinetics of nifedipine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of verapamil and diltiazem on the pharmacokinetics and pharmacodynamics of buspirone

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triazolam is ineffective in patients taking rifampin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erythromycin coadministration increases plasma atorvastatin concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diltiazem enhances the effects of triazolam by inhibiting its metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sorivudine and 5-fluorouracil; a clinically significant drug-drug interaction due to inhibition of dihydropyrimidine dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Itraconazole alters the pharmacokinetics of atorvastatin to a greater extent than either cerivastatin or pravastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cimetidine and ranitidine increase midazolam bioavailability.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and transport of the macrolide immunosuppressant sirolimus in the small intestine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interaction of diltiazem with simvastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The xenobiotic inhibitor profile of cytochrome P4502C8.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A potentially hazardous interaction between erythromycin and midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospective study of the safety and financial benefit of ketoconazole as adjunctive therapy to cyclosporine after heart transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and hemodynamic effects of nisoldipine and its interaction with cimetidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic contribution to variable human CYP3A-mediated metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of voriconazole on the pharmacokinetics of cyclosporine in renal transplant patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of two histamine H2-receptor antagonists, cimetidine and ranitidine, on the plasma levels and clinical effect of nifedipine and metoprolol

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of parallel pathways of drug elimination and multiple cytochrome P450 involvement on drug-drug interactions: CYP2D6 paradigm.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism-based inactivation of human cytochrome p450 enzymes and the prediction of drug-drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of roxithromycin on the pharmacokinetics of lovastatin in volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of in vivo drug-drug interactions from in vitro data : factors affecting prototypic drug-drug interactions involving CYP2C9, CYP2D6 and CYP3A4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of the systemic antimycotics, itraconazole and fluconazole, on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetics affects dosing, efficacy, and toxicity of cytochrome P450-metabolized drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of itraconazole metabolites in CYP3A4 inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of erythromycin pre- and co-treatment on single-dose pharmacokinetics of the HMG-CoA reductase inhibitor cerivastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic and Pharmacodynamic Interactions of Oral Midazolam with Ketoconazole, Fluoxetine, Fluvoxamine, and Nefazodone

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of midazolam and simvastatin as cytochrome P450 3A probes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of interaction between zolpidem and H2 antagonists, cimetidine and ranitidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible involvement of multiple P-glycoprotein-mediated efflux systems in the transport of verapamil and other organic cations across rat intestine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspective.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of the antibiotics erythromycin and azithromycin on the pharmacokinetics and pharmacodynamics of midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of ketoconazole on the pharmacokinetics, pharmacodynamics and safety of nisoldipine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of in vivo drug-drug interactions from in vitro data: impact of incorporating parallel pathways of drug elimination and inhibitor absorption rate constant

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: effect of ketoconazole.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative prediction of in vivo drug-drug interactions from in vitro data based on physiological pharmacokinetics: use of maximum unbound concentration of inhibitor at the inlet to the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP3A4 substrate selection and substitution in the prediction of potential drug-drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of itraconazole on the single oral dose pharmacokinetics and pharmacodynamics of alprazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of itraconazole on the pharmacokinetics and pharmacodynamics of zolpidem

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human cytochrome P-450 3A4: in vitro drug-drug interaction patterns are substrate-dependent.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma buspirone concentrations are greatly increased by erythromycin and itraconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ketoconazole effectively reverses multidrug resistance in highly resistant KB cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Withdrawal of cerivastatin from the world market

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between midazolam and clarithromycin: comparison with azithromycin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue distribution and chemical induction of multiple drug resistance genes in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of itraconazole on the pharmacokinetics of atorvastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporin-erythromycin interaction in normal subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reaction phenotyping in drug discovery: moving forward with confidence?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of cimetidine with the triazolobenzodiazepines alprazolam and triazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between cyclosporine and fluconazole in renal allograft recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pharmacokinetic interaction between roxithromycin and midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ketoconazole inhibition of triazolam and alprazolam clearance: differential kinetic and dynamic consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Azithromycin does not increase plasma concentrations of oral midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of itraconazole and terbinafine on the pharmacokinetics and pharmacodynamics of midazolam in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Database analyses for the prediction of in vivo drug-drug interactions from in vitro data

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of midazolam-CYP3A inhibitors interaction in the human liver from in vivo/in vitro absorption, distribution, and metabolism data.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification of the pharmacokinetics of cyclosporine A and metabolites by the concomitant use of Neoral and diltiazem or ketoconazol in stable adult kidney transplants

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic pharmacodynamic evaluation of the combined administration of alprazolam and fluoxetine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of voriconazole on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of H2 receptor antagonists on the plasma concentrations of midazolam and temazepam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of in vivo interaction between triazolam and erythromycin based on in vitro studies using human liver microsomes and recombinant human CYP3A4

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of fluvoxamine on the pharmacokinetics and pharmacodynamics of buspirone

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minimal interaction between fluoxetine and multiple-dose zolpidem in healthy women.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interaction of diltiazem with lovastatin and pravastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450-inducing antiepileptics increase the clearance of vincristine in patients with brain tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study of the interaction potential of azithromycin and clarithromycin with atorvastatin in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The utility of in vitro cytochrome P450 inhibition data in the prediction of drug-drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pharmacokinetic evaluation of the combined administration of triazolam and fluoxetine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP3A4 drug interactions: correlation of 10 in vitro probe substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism for the interaction between triazolam and cimetidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nifedipine-rifampin interaction. Evidence for induction of gut wall metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of fluconazole dose on the extent of fluconazole-triazolam interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pharmacokinetic and pharmacodynamic evaluation of the combined administration of alprazolam and fluvoxamine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pharmacokinetic drug interaction between erythromycin and triazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

H1-receptor antagonists: safety issues

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in alprazolam metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coadministration of nefazodone and benzodiazepines: III. A pharmacokinetic interaction study with alprazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An in vitro model for predicting in vivo inhibition of cytochrome P450 3A4 by metabolic intermediate complex formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of cytochrome P450 3A inhibition by verapamil enantiomers and their metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of itraconazole on cerivastatin pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of ketoconazole on the pharmacokinetics of rosiglitazone in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coadministration of nefazodone and benzodiazepines: II. A pharmacokinetic interaction study with triazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic and dynamic interaction study of zolpidem with ketoconazole, itraconazole, and fluconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of time-dependent CYP3A4 drug-drug interactions: impact of enzyme degradation, parallel elimination pathways, and intestinal inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noninvasive tests of CYP3A enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of saquinavir on the pharmacokinetics and pharmacodynamics of oral and intravenous midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced effect of triazolam with diltiazem

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of buspirone with itraconazole and rifampicin: effects on the pharmacokinetics of the active 1-(2-pyrimidinyl)-piperazine metabolite of buspirone

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of itraconazole or grapefruit juice on the pharmacokinetics of telithromycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of atypical cytochrome P450 kinetics with two-substrate models: evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Itraconazole greatly increases plasma concentrations and effects of felodipine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different effects of itraconazole on the pharmacokinetics of fluvastatin and lovastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erythromycin-felodipine interaction: Magnitude, mechanism, and comparison with grapefruit juice*

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic consequences of long term coadministration of cimetidine and triazolobenzodiazepines, alprazolam and triazolam, in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential mechanism-based inhibition of CYP3A4 and CYP3A5 by verapamil

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Open-label, nonrandomized study of the effects of gatifloxacin on the pharmacokinetics of midazolam in healthy male volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interactions between microemulsion formulated cyclosporine A and diltiazem in renal transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluoxetine impairs clearance of alprazolam but not of clonazepam

1 reference

https://pubmed.ncbi.nlm.nih.gov/17655375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00003088-200746080-00005

1 reference

Europe PubMed Central

3 August 2017

Dimensions Publication ID

0 references

release_mnnwni7sinende5xqat6r56mzq

1 reference

https://api.fatcat.wiki/v0/release/mnnwni7sinende5xqat6r56mzq

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

3 August 2017

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