(Q39949537)

15 September 2017

The selective COX-2 inhibitor celecoxib modulates sphingolipid synthesis (English)

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15 September 2017

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Susanne Schiffmann

1

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author name string

Jessica Sandner

2

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15 September 2017

Ronald Schmidt

3

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15 September 2017

Kerstin Birod

4

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15 September 2017

Ivonne Wobst

5

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15 September 2017

Helmut Schmidt

6

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15 September 2017

Carlo Angioni

7

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15 September 2017

Gerd Geisslinger

8

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15 September 2017

Sabine Grösch

9

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15 September 2017

18 August 2008

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Journal of Lipid Research

15 September 2017

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15 September 2017

50

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15 September 2017

1

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15 September 2017

32-40

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Ceramide in apoptosis: an overview and current perspectives

15 September 2017

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https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Intracellular signal transduction pathways activated by ceramide and its metabolites

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Principles of bioactive lipid signalling: lessons from sphingolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: Insights into the regulation of ceramide synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Altering the sphingosine-1-phosphate/ceramide balance: a promising approach for tumor therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Sphingosine kinase-1--a potential therapeutic target in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Mechanisms underlying the growth inhibitory effects of the cyclo-oxygenase-2 inhibitor celecoxib in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Celecoxib for the prevention of colorectal adenomatous polyps

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Celecoxib for the prevention of sporadic colorectal adenomas

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Mechanisms involved in exogenous C2- and C6-ceramide-induced cancer cell toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

3-phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Sequential caspase-2 and caspase-8 activation upstream of mitochondria during ceramideand etoposide-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Taxol-induced ceramide generation and apoptosis in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Functions of ceramide in coordinating cellular responses to stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Identification and characterization of a sphingolipid delta 4-desaturase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Cholesterol-like effects of selective cyclooxygenase inhibitors and fibrates on cellular membranes and amyloid-beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Role of cholesterol and lipid organization in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

The cyclo-oxygenase-2 inhibitor celecoxib perturbs intracellular calcium by inhibiting endoplasmic reticulum Ca2+-ATPases: a plausible link with its anti-tumour effect and cardiovascular risks

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Synthesis and biological activity of a novel inhibitor of dihydroceramide desaturase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

gamma-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Ceramide metabolite, not intact ceramide molecule, may be responsible for cellular toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

The CLN9 protein, a regulator of dihydroceramide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

Acid ceramidase inhibition: a novel target for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800122-JLR200

10.1194/JLR.M800122-JLR200

21 January 2018

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DOI

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15 September 2017

1 reference