(Q39992436)

16 September 2017

title

The BH3-only member Noxa causes apoptosis in melanoma cells by multiple pathways (English)

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16 September 2017

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7

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16 September 2017

M Hassan

1

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16 September 2017

A Alaoui

2

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16 September 2017

O Feyen

3

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16 September 2017

A Mirmohammadsadegh

4

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16 September 2017

F Essmann

5

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16 September 2017

A Tannapfel

6

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16 September 2017

K Schulze-Osthoff

8

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16 September 2017

U R Hengge

9

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16 September 2017

language of work or name

English

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publication date

14 April 2008

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16 September 2017

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16 September 2017

volume

27

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16 September 2017

issue

33

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16 September 2017

page(s)

4557-4568

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https://scigraph.springernature.com/pub.10.1038/onc.2008.90

16 September 2017

exact match

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cites work

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Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

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Comparison of immunohistochemistry for activated caspase-3 and cleaved cytokeratin 18 with the TUNEL method for quantification of apoptosis in histological sections of PC-3 subcutaneous xenografts

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Staphylococcus aureus alpha-toxin-induced cell death: predominant necrosis despite apoptotic caspase activation

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Irradiation-induced translocation of p53 to mitochondria in the absence of apoptosis

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Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

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Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications.

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Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway

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Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma

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Activation of RB/E2F signaling pathway is required for the modulation of hepatitis C virus core protein-induced cell growth in liver and non-liver cells.

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Activation of c-Jun NH2-terminal kinase (JNK) signaling pathway is essential for the stimulation of hepatitis C virus (HCV) non-structural protein 3 (NS3)-mediated cell growth.

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Identification of functional genes during Fas-mediated apoptosis using a randomly fragmented cDNA library.

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Induction of high-molecular-weight (HMW) tumor necrosis factor(TNF) alpha by hepatitis C virus (HCV) non-structural protein 3 (NS3) in liver cells is AP-1 and NF-kappaB-dependent activation.

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Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis

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Continuous intrathecal infusion of SB203580, a selective inhibitor of p38 mitogen-activated protein kinase, reduces the damage of hind-limb function after thoracic spinal cord injury in rat

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Conditional expression of exogenous Bcl-X(S) triggers apoptosis in human melanoma cells in vitro and delays growth of melanoma xenografts

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A novel Bcl-x splice product, Bcl-xAK, triggers apoptosis in human melanoma cells without BH3 domain

31 March 2020

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BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

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IL-2 gene expression and NF-kappa B activation through CD28 requires reactive oxygen production by 5-lipoxygenase

31 March 2020

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

31 March 2020

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31 March 2020

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The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice

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The BH3-mimetic GX15-070 synergizes with bortezomib in mantle cell lymphoma by enhancing Noxa-mediated activation of Bak

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Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membrane depolarization

31 March 2020

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BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.90

Integral role of Noxa in p53-mediated apoptotic response

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.90

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.90

Apoptosis and melanoma chemoresistance

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.90

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.90

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

31 March 2020

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.90

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.90

The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.90

Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.90

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.90

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Dimensions Publication ID

16 September 2017

1037578482

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1 reference