(Q40008373)

16 September 2017

title

A novel humanized anti-human death receptor 5 antibody CS-1008 induces apoptosis in tumor cells without toxicity in hepatocytes (English)

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16 September 2017

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A Yada

1

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16 September 2017

M Yazawa

2

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16 September 2017

S Ishida

3

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16 September 2017

H Yoshida

4

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16 September 2017

K Ichikawa

5

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16 September 2017

S Kurakata

6

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16 September 2017

K Fujiwara

7

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16 September 2017

publication date

27 February 2008

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16 September 2017

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16 September 2017

volume

19

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16 September 2017

issue

6

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16 September 2017

page(s)

1060-1067

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Mechanisms of apoptosis through structural biology

16 September 2017

cites work

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Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5

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FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death

21 January 2018

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Expression of tumor necrosis factor--related apoptosis-inducing ligand receptors 1 and 2 in melanoma

21 January 2018

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Functional expression of TRAIL receptors TRAIL-R1 and TRAIL-R2 in esophageal adenocarcinoma

21 January 2018

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21 January 2018

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Tissue distribution of the death ligand TRAIL and its receptors.

21 January 2018

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Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

21 January 2018

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Anti-tumor activity of TRA-8 anti-death receptor 5 (DR5) monoclonal antibody in combination with chemotherapy and radiation therapy in a cervical cancer model

21 January 2018

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Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2

21 January 2018

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Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

21 January 2018

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HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo

21 January 2018

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Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy.

21 January 2018

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Inactivating mutations of caspase-8 gene in colorectal carcinomas.

21 January 2018

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Cellular IAP1 regulates TRAIL-induced apoptosis in human fetal cortical neural progenitor cells.

21 January 2018

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Role of death receptor and mitochondrial pathways in conventional chemotherapy drug induction of apoptosis

21 January 2018

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Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis

21 January 2018

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Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

21 January 2018

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Effects of sequential treatments with chemotherapeutic drugs followed by TRAIL on prostate cancer in vitro and in vivo

21 January 2018

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Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells

21 January 2018

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Enhancement of TRAIL/Apo2L-mediated apoptosis by adriamycin through inducing DR4 and DR5 in renal cell carcinoma cells

21 January 2018

1 reference

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Synergistic induction of tumor cell apoptosis by death receptor antibody and chemotherapy agent through JNK/p38 and mitochondrial death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDN015

The anti-tumor effect of Apo2L/TRAIL on patient pancreatic adenocarcinomas grown as xenografts in SCID mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDN015

21 January 2018

Identifiers

DOI

10.1093/ANNONC/MDN015

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16 September 2017

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