(Q40015743)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

Intron-3 retention/splicing controls neuronal expression of apolipoprotein E in the CNS (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

author name string

Qin Xu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

David Walker

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Aubrey Bernardo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Jens Brodbeck

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Maureen E Balestra

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Yadong Huang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

language of work or name

English

0 references

publication date

1 February 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

page(s)

1452-1459

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

Specific regional transcription of apolipoprotein E in human brain neurons

2 January 2020

cites work

1 reference

12 December 2020

Association of apolipoprotein E polymorphism with outcome after head injury.

1 reference

12 December 2020

Tissue-specific alternative mRNA splicing of phenylethanolamine N-methyltransferase (PNMT) during development by intron retention

1 reference

12 December 2020

Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration.

1 reference

12 December 2020

Truncated apolipoprotein E (ApoE) causes increased intracellular calcium and may mediate ApoE neurotoxicity.

1 reference

12 December 2020

Enhanced splicing of the first intron from the gonadotropin-releasing hormone (GnRH) primary transcript is a prerequisite for mature GnRH messenger RNA: presence of GnRH neuron-specific splicing factors

1 reference

12 December 2020

Nuclear retention elements of U3 small nucleolar RNA

1 reference

12 December 2020

Apolipoprotein E expression by neurons surviving excitotoxic stress

1 reference

12 December 2020

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

1 reference

12 December 2020

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice

1 reference

12 December 2020

Isolation and characterization of apolipoproteins from murine microglia. Identification of a low density lipoprotein-like apolipoprotein J-rich but E-poor spherical particle

1 reference

12 December 2020

Two distal downstream enhancers direct expression of the human apolipoprotein E gene to astrocytes in the brain.

1 reference

12 December 2020

Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons

1 reference

12 December 2020

Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis

1 reference

12 December 2020

Apolipoprotein E4 potentiates amyloid beta peptide-induced lysosomal leakage and apoptosis in neuronal cells

1 reference

12 December 2020

APOE: a potential marker of disease progression in ALS

1 reference

12 December 2020

Androgens protect against apolipoprotein E4-induced cognitive deficits

1 reference

12 December 2020

Selecting for functional alternative splices in ESTs

1 reference

12 December 2020

Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.

1 reference

12 December 2020

Neuronal apolipoprotein E is not synthesized in neuron after focal ischemia in rat brain

1 reference

12 December 2020

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

1 reference

12 December 2020

Astroglial regulation of apolipoprotein E expression in neuronal cells. Implications for Alzheimer's disease

1 reference

12 December 2020

Association of APOE polymorphisms with disease severity in MS is limited to women.

1 reference

12 December 2020

Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.

1 reference

12 December 2020

Detection and evaluation of intron retention events in the human transcriptome.

1 reference

12 December 2020

Apolipoprotein E: diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease

1 reference

12 December 2020

Apolipoprotein E controls the risk and age at onset of Parkinson disease

1 reference

12 December 2020

Increased tau phosphorylation in apolipoprotein E4 transgenic mice is associated with activation of extracellular signal-regulated kinase: modulation by zinc

1 reference

12 December 2020

Cyclooxygenase-3 gene expression in Alzheimer hippocampus and in stressed human neural cells

1 reference

12 December 2020

Cloning and characterization of mouse mTERF encoding a mitochondrial transcriptional termination factor

1 reference

12 December 2020

Sense and antisense transcripts of the apolipoprotein E gene in normal and ApoE knockout mice, their expression after spinal cord injury and corresponding human transcripts

1 reference

12 December 2020

Cloning, expression, and functional characterization of human cyclooxygenase-1 splicing variants: evidence for intron 1 retention

1 reference

12 December 2020

Developmental regulation of a proinsulin messenger RNA generated by intron retention.

1 reference

12 December 2020

Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target

1 reference

12 December 2020

Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity

1 reference

12 December 2020

Apolipoprotein E and Alzheimer disease.

1 reference

12 December 2020

Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease

1 reference

12 December 2020

Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus.

1 reference

12 December 2020

Molecular and cellular mechanisms of apolipoprotein E4 neurotoxicity and potential therapeutic strategies.

1 reference

12 December 2020

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

1 reference

12 December 2020

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

1 reference

12 December 2020

ApoE immunoreactivity and microglial cells in Alzheimer's disease brain.

1 reference

12 December 2020

ApoE genotype and survival from intracerebral haemorrhage

1 reference

12 December 2020

Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro

1 reference

12 December 2020

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

12 December 2020

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

12 December 2020

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

12 December 2020

Apolipoprotein E genotyping in sporadic amyotrophic lateral sclerosis: evidence for a major influence on the clinical presentation and prognosis.

1 reference

12 December 2020

Human apolipoprotein E: the Alzheimer's disease connection.

1 reference

12 December 2020

Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation.

1 reference

12 December 2020

Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo.

1 reference

12 December 2020

Neurotoxicity of the 22 kDa thrombin-cleavage fragment of apolipoprotein E and related synthetic peptides is receptor-mediated

1 reference

12 December 2020

Dissociation of apolipoprotein and apolipoprotein receptor response to lesion in the rat brain: an in situ hybridization study

1 reference

12 December 2020

Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females

1 reference

12 December 2020

10.1523/JNEUROSCI.3253-07.2008

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256266%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

PubMed publication ID

18256266

1 reference