(Q40034009)

16 September 2017

title

Resistance of cell lines to prion toxicity aided by phospho-ERK expression (English)

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16 September 2017

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Kay M Uppington

1

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16 September 2017

David R Brown

series ordinal

2

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16 September 2017

language of work or name

English

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publication date

15 December 2007

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Journal of Neurochemistry

16 September 2017

published in

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16 September 2017

volume

105

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16 September 2017

issue

3

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16 September 2017

page(s)

842-852

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Neuroprotection by BDNF against glutamate-induced apoptotic cell death is mediated by ERK and PI3-kinase pathways.

16 September 2017

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Involvement of ERK MAP kinase in endoplasmic reticulum stress in SH-SY5Y human neuroblastoma cells

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Scrapie strains maintain biological phenotypes on propagation in a cell line in culture

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Synthetic miniprion PrP106.

21 January 2018

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Alteration of NF-kappaB activity leads to mitochondrial apoptosis after infection with pathological prion protein

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Normal host prion protein necessary for scrapie-induced neurotoxicity.

21 January 2018

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Prion protein peptide neurotoxicity can be mediated by astrocytes

21 January 2018

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Prion and prejudice: normal protein and the synapse

21 January 2018

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Mayhem of the multiple mechanisms: modelling neurodegeneration in prion disease

21 January 2018

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Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.

21 January 2018

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The cellular prion protein binds copper in vivo

21 January 2018

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Consequences of manganese replacement of copper for prion protein function and proteinase resistance

21 January 2018

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Lack of prion protein expression results in a neuronal phenotype sensitive to stress

21 January 2018

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Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

21 January 2018

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Activation of the JNK-c-Jun pathway during the early phase of neuronal apoptosis induced by PrP106-126 and prion infection.

21 January 2018

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Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

21 January 2018

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Pathologic conformations of prion proteins

21 January 2018

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Prion protein fragment 106-126 induces a p38 MAP kinase-dependent apoptosis in SH-SY5Y neuroblastoma cells independently from the amyloid fibril formation.

21 January 2018

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Toxicity of novel C-terminal prion protein fragments and peptides harbouring disease-related C-terminal mutations.

21 January 2018

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Neurotoxicity of a prion protein fragment.

21 January 2018

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Dendritic pathology in prion disease starts at the synaptic spine.

21 January 2018

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Hereditary Creutzfeldt-Jakob disease and fatal familial insomnia.

21 January 2018

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Hereditary prion protein amyloidoses

21 January 2018

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Neuronal cell death in scrapie-infected mice is due to apoptosis

21 January 2018

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Variant Creutzfeldt-jakob disease: between lymphoid organs and brain

21 January 2018

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A transmembrane form of the prion protein in neurodegenerative disease

21 January 2018

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Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.

21 January 2018

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A novel method of generating neuronal cell lines from gene-knockout mice to study prion protein membrane orientation.

21 January 2018

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Fibrils from brains of cows with new cattle disease contain scrapie-associated protein

21 January 2018

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Scrapie and experimental BSE in sheep

21 January 2018

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Phenotypic variability in human prion diseases.

21 January 2018

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

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An unusual soluble beta-turn-rich conformation of prion is involved in fibril formation and toxic to neuronal cells.

21 January 2018

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21 January 2018

1 reference

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Activation of mitogen-activated protein kinases in hamster brains infected with 263K scrapie agent.

21 January 2018

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Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

21 January 2018

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Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

Pathological prion protein exposure switches on neuronal mitogen-activated protein kinase pathway resulting in microglia recruitment

21 January 2018

1 reference

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Inherited prion disease with six octapeptide repeat insertional mutation--molecular analysis of phenotypic heterogeneity.

21 January 2018

1 reference

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Heterogeneity and regulation of cellular prion protein glycoforms in neuronal cell lines.

21 January 2018

1 reference

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Cytoprotective effect of NMDA receptor antagonists on prion protein (PrionSc)-induced toxicity in rat cortical cell cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

Cellular prion protein localization in rodent and primate brain.

21 January 2018

1 reference

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The most infectious prion protein particles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

In vitro and in vivo neurotoxicity of prion protein oligomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

Scrapie prion protein contains a phosphatidylinositol glycolipid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

Metal imbalance and compromised antioxidant function are early changes in prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

High affinity binding between copper and full-length prion protein identified by two different techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

Acquired prion disease: iatrogenic CJD, variant CJD, kuru

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

Copper refolding of prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

Amyloid Fibrils of Mammalian Prion Protein Are Highly Toxic to Cultured Cells and Primary Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05192.X

10.1111/J.1471-4159.2007.05192.X

21 January 2018

Identifiers

DOI

1 reference

16 September 2017

1 reference