(Q40036535)

English

Oral co-administration of elacridar and ritonavir enhances plasma levels of oral paclitaxel and docetaxel without affecting relative brain accumulation

scientific article published on 29 April 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Oral co-administration of elacridar and ritonavir enhances plasma levels of oral paclitaxel and docetaxel without affecting relative brain accumulation (English)

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

6

object named as

J H Beijnen

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

author name string

J J M A Hendrikx

1

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

J S Lagas

2

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

E Wagenaar

3

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

H Rosing

4

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

J H M Schellens

5

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

A H Schinkel

7

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

language of work or name

0 references

publication date

29 April 2014

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

British Journal of Cancer

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

110

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

11

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

2669-2676

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

https://scigraph.springernature.com/pub.10.1038/bjc.2014.222

0 references

Why clinical modulation of efflux transport at the human blood-brain barrier is unlikely: the ITC evidence-based position.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Oral anticancer drugs: mechanisms of low bioavailability and strategies for improvement.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Pharmacogenetics of taxanes: impact of gene polymorphisms of drug transporters on pharmacokinetics and toxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Rate of onset of inhibition of gut-wall and hepatic CYP3A by clarithromycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Population pharmacokinetics of intravenously and orally administered docetaxel with or without co-administration of ritonavir in patients with advanced cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Low-dose metronomic paclitaxel chemotherapy suppresses breast tumors and metastases in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Intravenous-to-oral switch in anticancer chemotherapy: a focus on docetaxel and paclitaxel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Nuclear receptors CAR and PXR: Molecular, functional, and biomedical aspects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Cytochrome P450-mediated metabolism in the human gut wall

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

The human intestinal cytochrome P450 "pie".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Induction of phase I, II and III drug metabolism/transport by xenobiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Quantitative analysis of docetaxel in human plasma using liquid chromatography coupled with tandem mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Genetics of the variable expression of CYP3A in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Preclinical pharmacology of the taxanes: implications of the differences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Increased penetration of paclitaxel into the brain by inhibition of P-Glycoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Overview: ABC transporters and human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Co-administration of GF120918 significantly increases the systemic exposure to oral paclitaxel in cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Modulation of oral bioavailability of anticancer drugs: from mouse to man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Taxanes: an overview of the pharmacokinetics and pharmacodynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

22 September 2017

Metronomic docetaxel chemotherapy inhibits angiogenesis and tumor growth in a gastric cancer model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

20 August 2018

Absence of both cytochrome P450 3A and P-glycoprotein dramatically increases docetaxel oral bioavailability and risk of intestinal toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

20 August 2018

Coadministration of ritonavir strongly enhances the apparent oral bioavailability of docetaxel in patients with solid tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

20 August 2018

A simple and sensitive assay for the quantitative analysis of paclitaxel in human and mouse plasma and brain tumor tissue using coupled liquid chromatography and tandem mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

20 August 2018

Efficacy of novel P-glycoprotein inhibitors to increase the oral uptake of paclitaxel in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

20 August 2018

Low systemic exposure of oral docetaxel in mice resulting from extensive first-pass metabolism is boosted by ritonavir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

20 August 2018

Increased oral bioavailability of paclitaxel by GF120918 in mice through selective modulation of P-glycoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037831

20 August 2018

Anaemia after enalapril in a child with nephrotic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2014.222

21 January 2018

Co-administration of cyclosporin enables oral therapy with paclitaxel

1 reference

https://pubmed.ncbi.nlm.nih.gov/24781280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced oral absorption and decreased elimination of paclitaxel in mice cotreated with cyclosporin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/24781280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance protein 2 is an important determinant of paclitaxel pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/24781280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal models and intestinal drug transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/24781280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel

1 reference

https://pubmed.ncbi.nlm.nih.gov/24781280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/BJC.2014.222

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

ResearchGate publication ID

0 references

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