(Q40037259)

English

4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas.

scientific article published on 11 December 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas. (English)

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

author name string

Rajendra Sharma

1

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Abha Sharma

2

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Seema Dwivedi

3

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Piotr Zimniak

4

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Sanjay Awasthi

5

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Yogesh C Awasthi

6

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

language of work or name

0 references

publication date

11 December 2007

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

47

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

1

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

143-156

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Heat shock factor 1 attenuates 4-Hydroxynonenal-mediated apoptosis: critical role for heat shock protein 70 induction and stabilization of Bcl-XL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Inhibition of thioredoxin and thioredoxin reductase by 4-hydroxy-2-nonenal in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Daxx: death or survival protein?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Depletion of 4-hydroxynonenal in hGSTA4-transfected HLE B-3 cells results in profound changes in gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Inhibition of Hsp72-mediated protein refolding by 4-hydroxy-2-nonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

4-hydroxynonenal and regulation of cell cycle: effects on the pRb/E2F pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

DAXX interacts with heat shock factor 1 during stress activation and enhances its transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Daxx Silencing Sensitizes Cells to Multiple Apoptotic Pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

4-hydroxynonenal from pathology to physiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Oxidized LDL and 4-hydroxynonenal modulate tyrosine kinase receptor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

4-hydroxynonenal triggers multistep signal transduction cascades for suppression of cellular functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Role of 4-hydroxynonenal in stress-mediated apoptosis signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Role of PKC-dependent pathways in HNE-induced cell protein transport and secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Live or let die: the cell's response to p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

AP-1: linking hydrogen peroxide and oxidative stress to the control of cell proliferation and death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Phenolic antioxidants trolox and caffeic acid modulate the oxidized LDL-induced EGF-receptor activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Role of p53 and apoptosis in carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Regulation of JNK signaling by GSTp

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

HNE interacts directly with JNK isoforms in human hepatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Daxx, a novel Fas-binding protein that activates JNK and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Apoptosis by death factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

The DNA-binding activity of the human heat shock transcription factor is regulated in vivo by hsp70.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

Selective cleavage of thioether linkage in proteins modified with 4-hydroxynonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

22 September 2017

4-hydroxynonenal induces glutamate cysteine ligase through JNK in HBE1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

25 September 2017

The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

25 September 2017

4-hydroxynonenal triggers an epidermal growth factor receptor-linked signal pathway for growth inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

25 September 2017

Regulation of CD95 (Fas) expression and Fas-mediated apoptotic signaling in HLE B-3 cells by 4-hydroxynonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

15 June 2018

Cells preconditioned with mild, transient UVA irradiation acquire resistance to oxidative stress and UVA-induced apoptosis: role of 4-hydroxynonenal in UVA-mediated signaling for apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

15 June 2018

Mildly oxidized LDL induces activation of platelet-derived growth factor beta-receptor pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

15 June 2018

Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

15 June 2018

Regulation of 4-hydroxynonenal mediated signaling by glutathione S-transferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

20 August 2018

Modification of heat shock protein 90 by 4-hydroxynonenal in a rat model of chronic alcoholic liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

20 August 2018

Daxx is required for stress-induced cell death and JNK activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

20 August 2018

Expression of a dominant negative form of Daxx in vivo rescues motoneurons from Fas (CD95)-induced cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

20 August 2018

A caspase-8-independent signaling pathway activated by Fas ligation leads to exposure of the Bak N terminus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

20 August 2018

Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

20 August 2018

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2564820

20 August 2018

RNAi reveals anti-apoptotic and transcriptionally repressive activities of DAXX

1 reference

https://pubmed.ncbi.nlm.nih.gov/18069800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1 reference

https://pubmed.ncbi.nlm.nih.gov/18069800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-Fas IgG1 antibodies recognizing the same epitope of Fas/APO-1 mediate different biological effects in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18069800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Daxx overexpression in T-lymphoblastic Jurkat cells enhances caspase-dependent death receptor- and drug-induced apoptosis in distinct ways

1 reference

https://pubmed.ncbi.nlm.nih.gov/18069800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI701559F

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

release_ekwf42u6qnecvlamngdd3sdlfy

1 reference

https://api.fatcat.wiki/v0/release/ekwf42u6qnecvlamngdd3sdlfy

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

ResearchGate publication ID

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