(Q40052220)

16 September 2017

title

Probing novel 1-aza-9-oxafluorenes as selective GSK-3beta inhibitors (English)

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16 September 2017

3

Christoph Schächtele

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author name string

Burkhardt Voigt

1

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16 September 2017

Martin Krug

2

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16 September 2017

Christoph Schächtele

3

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16 September 2017

Frank Totzke

4

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16 September 2017

Andreas Hilgeroth

5

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16 September 2017

publication date

1 January 2008

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16 September 2017

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16 September 2017

volume

3

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16 September 2017

issue

1

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16 September 2017

page(s)

120-126

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New trends in the design of drugs against Alzheimer's disease

16 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700175

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

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Amyloid plaque core protein in Alzheimer disease and Down syndrome

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7 January 2021

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease

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https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

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https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

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https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

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https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

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https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II.

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https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

Cdk5 is a key factor in tau aggregation and tangle formation in vivo.

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https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation.

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https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

Paullones, a series of cyclin-dependent kinase inhibitors: synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

Pharmacological inhibitors of glycogen synthase kinase 3.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

GSK3 inhibitors: development and therapeutic potential

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

Evaluation of the first cytostatically active 1-aza-9-oxafluorenes as novel selective CDK1 inhibitors with P-glycoprotein modulating properties

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

Structure-aided optimization of kinase inhibitors derived from alsterpaullone.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

Development and validation of a genetic algorithm for flexible docking

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

7-Bromoindirubin-3'-oxime induces caspase-independent cell death

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700175

7 January 2021

Identifiers

DOI

10.1002/CMDC.200700175

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16 September 2017

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