(Q40102845)

17 September 2017

title

Enhanced lysosomal pathology caused by beta-synuclein mutants linked to dementia with Lewy bodies (English)

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17 September 2017

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5

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Edward Rockenstein

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17 September 2017

8

Eliezer Masliah

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17 September 2017

Jianshe Wei

1

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17 September 2017

Masayo Fujita

2

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17 September 2017

Masaaki Nakai

3

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17 September 2017

Masaaki Waragai

4

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17 September 2017

Hiroyasu Akatsu

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17 September 2017

Makoto Hashimoto

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17 September 2017

language of work or name

English

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publication date

24 July 2007

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Journal of Biological Chemistry

17 September 2017

published in

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17 September 2017

volume

282

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17 September 2017

issue

39

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17 September 2017

page(s)

28904-28914

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Alpha-synuclein in Lewy body disease and Alzheimer's disease

17 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Alpha-synuclein in Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

The E46K mutation in alpha-synuclein increases amyloid fibril formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Beta-synuclein modulates alpha-synuclein neurotoxicity by reducing alpha-synuclein protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Biophysical properties of the synucleins and their propensities to fibrillate: inhibition of alpha-synuclein assembly by beta- and gamma-synucleins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Beta-synuclein regulates Akt activity in neuronal cells. A possible mechanism for neuroprotection in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Degradative organelles containing mislocalized alpha-and beta-synuclein proliferate in presenilin-1 null neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Beta-synuclein gene alterations in dementia with Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Non-A.beta. Component of Alzheimer's Disease Amyloid (NAC) is Amyloidogenic

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Reduced neuritic outgrowth and cell adhesion in neuronal cells transfected with human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Generation of murine monoclonal antibodies specific for N-glycolylneuraminic acid-containing gangliosides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

NACP, a synaptic protein involved in Alzheimer's disease, is differentially regulated during megakaryocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

alpha-Synuclein stimulates differentiation of osteosarcoma cells: relevance to down-regulation of proteasome activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Beta-synuclein displays an antiapoptotic p53-dependent phenotype and protects neurons from 6-hydroxydopamine-induced caspase 3 activation: cross-talk with alpha-synuclein and implication for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Aggresomes, inclusion bodies and protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Forcing nonamyloidogenic beta-synuclein to fibrillate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Synphilin-1A: an aggregation-prone isoform of synphilin-1 that causes neuronal death and is present in aggregates from alpha-synucleinopathy patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

The neuropathogenic contributions of lysosomal dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Degeneration of neuronal processes in rats induced by a protease inhibitor, leupeptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Neuronal loss and brain atrophy in mice lacking cathepsins B and L

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Calpain-cleavage of alpha-synuclein: connecting proteolytic processing to disease-linked aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

ATP13A2 missense mutations in juvenile parkinsonism and young onset Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703711200

21 January 2018

Identifiers

DOI

10.1074/JBC.M703711200

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17 September 2017

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