(Q40126914)

17 September 2017

title

Indirubin-3'-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK. (English)

1 reference

17 September 2017

Zhen Y

1

1 reference

17 September 2017

Sørensen V

2

1 reference

17 September 2017

Jin Y

3

1 reference

17 September 2017

Suo Z

4

1 reference

17 September 2017

Wiedłocha A

5

1 reference

17 September 2017

language of work or name

English

0 references

publication date

28 May 2007

1 reference

17 September 2017

1 reference

17 September 2017

volume

26

1 reference

17 September 2017

issue

44

1 reference

17 September 2017

page(s)

6372-6385

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210473

17 September 2017

exact match

0 references

cites work

Indirubin and indigo are potent aryl hydrocarbon receptor ligands present in human urine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

FGF signals for cell proliferation and migration through different pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Mechanism of p38 MAP kinase activation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Regulation of cyclin-dependent kinase (Cdk) 2 Thr-160 phosphorylation and activity by mitogen-activated protein kinase in late G1 phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Mechanisms underlying differential responses to FGF signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Inhibitor binding to active and inactive CDK2: the crystal structure of CDK2-cyclin A/indirubin-5-sulphonate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Cellular signaling by fibroblast growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

8p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Cell cycle-dependent nuclear localization of exogenously added fibroblast growth factor-1 in BALB/c 3T3 and human vascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Evolution of the Fgf and Fgfr gene families

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Multiple activation mechanisms of p38alpha mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Cyclin-dependent kinase 2 nucleocytoplasmic translocation is regulated by extracellular regulated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison with ligand binding to pCDK2-cyclin A complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Stimulation of the Raf/MEK/ERK cascade is necessary and sufficient for activation and Thr-160 phosphorylation of a nuclear-targeted CDK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Role of the p38 MAPK pathway in cisplatin-based therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

The intracellular genistein metabolite 5,7,3',4'-tetrahydroxyisoflavone mediates G2-M cell cycle arrest in cancer cells via modulation of the p38 signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

FGFs, heparan sulfate and FGFRs: complex interactions essential for development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Fibroblast growth factors, their receptors and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

7-Bromoindirubin-3'-oxime induces caspase-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

The stress-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Dual mode of signal transduction by externally added acidic fibroblast growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Indirubin-3'-oxime inhibits c-Jun NH2-terminal kinase: anti-apoptotic effect in cerebellar granule neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

Activation of mitogen-activated protein kinases by tributyltin in CCRF-CEM cells: role of intracellular Ca(2+).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

t(6;8), t(8;9) and t(8;13) translocations associated with stem cell myeloproliferative disorders have close or identical breakpoints in chromosome region 8p11-12

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

inferred from DOI database lookup

7 January 2021

based on heuristic

Indirubin-3'-monoxime, a derivative of a Chinese antileukemia medicine, inhibits P-TEFb function and HIV-1 replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210473

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1210473

1 reference

Dimensions Publication ID

17 September 2017

1031201335

0 references

1 reference