(Q40135335)

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Active Rap1, a small GTPase that induces malignant transformation of hematopoietic progenitors, localizes in the nucleus and regulates protein expression.

scientific article published on May 2007

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17487743%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Active Rap1, a small GTPase that induces malignant transformation of hematopoietic progenitors, localizes in the nucleus and regulates protein expression (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17487743%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Esther Lafuente

1

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30 December 2019

Christopher V. Carman

3

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30 December 2019

author name string

Yoshiko Iwamoto

2

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30 December 2019

André A F L van Puijenbroek

4

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30 December 2019

Erica Constantine

5

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30 December 2019

Lequn Li

6

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30 December 2019

Vassiliki A Boussiotis

7

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30 December 2019

publication date

1 May 2007

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Europe PubMed Central

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30 December 2019

Leukemia & Lymphoma

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17487743%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

48

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30 December 2019

5

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30 December 2019

987-1002

1 reference

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30 December 2019

A ras-related gene with transformation suppressor activity

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Inhibition of GTPase activating protein stimulation of Ras-p21 GTPase by the Krev-1 gene product

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Ultrastructural localization of the small GTP-binding protein Rap1 in human platelets and megakaryocytes.

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Relationships between Rap1b, affinity modulation of integrin alpha IIbbeta 3, and the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1.

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Rap1 GTPase: Functions, Regulation, and Malignancy

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Rap1 GTPase regulation of adherens junction positioning and cell adhesion.

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Rap1 regulates the formation of E-cadherin-based cell-cell contacts.

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Rap1 signalling: adhering to new models

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

The small GTPase Rap1 is required for Mn(2+)- and antibody-induced LFA-1- and VLA-4-mediated cell adhesion

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Rap1 is activated by erythropoietin or interleukin-3 and is involved in regulation of beta1 integrin-mediated hematopoietic cell adhesion

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Rap1A and rap1B ras-family proteins are prominently expressed in the nucleus of squamous carcinomas: nuclear translocation of GTP-bound active form.

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion.

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

A genome-wide survey of RAS transformation targets

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Identification of H-Ras, RhoA, Rac1 and Cdc42 responsive genes.

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Proteome analysis at the level of subcellular structures

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Focal adhesions - the cytoskeletal connection

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

VLA-4 mediates CD3-dependent CD4+ T cell activation via the CS1 alternatively spliced domain of fibronectin

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Integrin avidity regulation: are changes in affinity and conformation underemphasized?

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common beta 1 chain

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Role of p21ras in growth factor signal transduction

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

The Rap GTPases regulate integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 tyrosine phosphorylation in B lymphocytes

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Functional interaction between p21rap1A and components of the budding pathway in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

The small Mr Ras-like GTPase Rap1 and the phospholipase C pathway act to regulate phagocytosis in Dictyostelium discoideum

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins.

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Tyrosine phosphorylation of villin regulates the organization of the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

EPLIN, epithelial protein lost in neoplasm

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

AF-6 controls integrin-mediated cell adhesion by regulating Rap1 activation through the specific recruitment of Rap1GTP and SPA-1.

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Plakophilins 2a and 2b: constitutive proteins of dual location in the karyoplasm and the desmosomal plaque

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Interaction of c-Src with gap junction protein connexin-43. Role in the regulation of cell-cell communication

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Friends and family: the role of the Rab GTPases in vesicular traffic

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Regulation of clathrin assembly and trimerization defined using recombinant triskelion hubs

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Caveolin cycles between plasma membrane caveolae and the Golgi complex by microtubule-dependent and microtubule-independent steps

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Association of the Ras-antagonistic Rap1/Krev-1 proteins with the Golgi complex

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

AKAP149 is a novel PP1 specifier required to maintain nuclear envelope integrity in G1 phase

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Antisense inhibition of basic fibroblast growth factor induces apoptosis in vascular smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Unusual type of TLS/FUS-ERG chimeric transcript in a pediatric acute myelocytic leukemia with 47,XX,+10,t(16;21)(p11;q22).

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

PI31 is a modulator of proteasome formation and antigen processing

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Induction of autophagy and inhibition of tumorigenesis by beclin 1

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Genetic analysis of the Kirsten-ras-revertant 1 gene: potentiation of its tumor suppressor activity by specific point mutations

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Mitogenic and oncogenic properties of the small G protein Rap1b

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Activation of the Rap1 guanine nucleotide exchange gene, CalDAG-GEF I, in BXH-2 murine myeloid leukemia

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

DOCK4, a GTPase activator, is disrupted during tumorigenesis

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701242341

21 January 2018

Identifiers

10.1080/10428190701242341

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17487743%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17487743%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

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