(Q40175911)

English

Systematic uncovering of multiple pathways underlying the pathology of Huntington disease by an acid-cleavable isotope-coded affinity tag approach

scientific article published on 31 January 2007

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scholarly article

1 reference

Europe PubMed Central

18 September 2017

Systematic uncovering of multiple pathways underlying the pathology of Huntington disease by an acid-cleavable isotope-coded affinity tag approach (English)

1 reference

Europe PubMed Central

18 September 2017

Huntington's disease

0 references

6

1 reference

Europe PubMed Central

18 September 2017

author name string

Ming-Chang Chiang

1

1 reference

Europe PubMed Central

18 September 2017

Chiun-Gung Juo

2

1 reference

Europe PubMed Central

18 September 2017

Hao-Hung Chang

3

1 reference

Europe PubMed Central

18 September 2017

Hui-Mei Chen

4

1 reference

Europe PubMed Central

18 September 2017

Eugene C Yi

5

1 reference

Europe PubMed Central

18 September 2017

publication date

31 January 2007

1 reference

Europe PubMed Central

18 September 2017

Molecular & Cellular Proteomics

1 reference

Europe PubMed Central

18 September 2017

6

1 reference

Europe PubMed Central

18 September 2017

5

1 reference

Europe PubMed Central

18 September 2017

781-797

1 reference

Europe PubMed Central

18 September 2017

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Huntington's disease. Pathogenesis and management

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Recent advances in understanding the pathogenesis of Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Polyglutamine diseases: a transcription disorder?

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Interaction of Huntington disease protein with transcriptional activator Sp1

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

cAMP-response element-binding protein contributes to suppression of the A2A adenosine receptor promoter by mutant Huntingtin with expanded polyglutamine residues

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Proteomic analysis of protein expression and oxidative modification in r6/2 transgenic mice: a model of Huntington disease

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Direct analysis of protein complexes using mass spectrometry

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Mass spectrometric analysis of protein mixtures at low levels using cleavable 13C-isotope-coded affinity tag and multidimensional chromatography

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Fractionation of isotopically labeled peptides in quantitative proteomics

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

A microcapillary trap cartridge-microcapillary high-performance liquid chromatography electrospray ionization emitter device capable of peptide tandem mass spectrometry at the attomole level on an ion trap mass spectrometer with automated routine op

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Quantitative profiling of differentiation-induced microsomal proteins using isotope-coded affinity tags and mass spectrometry

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

A statistical model for identifying proteins by tandem mass spectrometry

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Automated statistical analysis of protein abundance ratios from data generated by stable-isotope dilution and tandem mass spectrometry

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

ST14A cells have properties of a medium-size spiny neuron.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Membrane filter assay for detection of amyloid-like polyglutamine-containing protein aggregates.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

System-based proteomic analysis of the interferon response in human liver cells

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Reduced activity and protein expression of NOS in R6/2 HD transgenic mice: effects of L-NAME on symptom progression

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Cytochrome C and caspase-9 expression in Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Two-dimensional gel electrophoresis; better than a poke in the ICAT?

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

14-3-3 proteins in the nervous system

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

The 14-3-3 protein forms a molecular complex with heat shock protein Hsp60 and cellular prion protein

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Transducible heat shock protein 20 (HSP20) phosphopeptide alters cytoskeletal dynamics

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Interactions between extracellular signal-regulated protein kinase 1, 14-3-3epsilon, and heat shock factor 1 during stress

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

The alternative role of 14-3-3 zeta as a sweeper of misfolded proteins in disease conditions.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Neuroimmunophilins: novel neuroprotective and neuroregenerative targets

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Neuroprotective effects of tacrolimus (FK506) in a model of ischemic cortical cell cultures: role of glutamate uptake and FK506 binding protein 12 kDa.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Multiple components of the HSP90 chaperone complex function in regulation of heat shock factor 1 In vivo

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

The heart LIM protein gene (Hlp), expressed in the developing and adult heart, defines a new tissue-specific LIM-only protein family.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

The loss of beta II-protein kinase C in the striatum from patients with Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Impaired synaptic plasticity in mice carrying the Huntington's disease mutation

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

An abnormal striatal synaptic plasticity may account for the selective neuronal vulnerability in Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

The nucleoskeleton: lamins and actin are major players in essential nuclear functions

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Microtubule destabilization and nuclear entry are sequential steps leading to toxicity in Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Plk phosphorylation regulates the microtubule-stabilizing protein TCTP.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Nuclear translocation of cytochrome c during apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase inhibitors as novel and broadly effective neuroprotective agents.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Striatal phosphodiesterase mRNA and protein levels are reduced in Huntington's disease transgenic mice prior to the onset of motor symptoms

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Multifaceted roles of glycolytic enzymes.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Alteration of nuclear glyceraldehyde-3-phosphate dehydrogenase structure in Huntington's disease fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Charting the proteomes of organisms with unsequenced genomes by MALDI-quadrupole time-of-flight mass spectrometry and BLAST homology searching

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Large-scale evaluation of quantitative reproducibility and proteome coverage using acid cleavable isotope coded affinity tag mass spectrometry for proteomic profiling.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Identification of neurite outgrowth-promoting domains of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan, and involvement of phosphatidylinositol 3-kinase and protein kinase C signaling pathways in neuritogenesis.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Overexpression of human peroxiredoxin 5 in subcellular compartments of Chinese hamster ovary cells: effects on cytotoxicity and DNA damage caused by peroxides

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Downregulation of peroxiredoxin V stimulates formation of etoposide-induced double-strand DNA breaks

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Huntington's disease. Unorthodox clinical trials meld science and care

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Chemistry meets proteomics: the use of chemical tagging reactions for MS-based proteomics

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Actin's many actions start at the genes

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600356-MCP200

21 January 2018

Identifiers

10.1074/MCP.M600356-MCP200

1 reference

Europe PubMed Central

18 September 2017

1 reference

Europe PubMed Central

18 September 2017

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