(Q40204086)

English

Zerumbone, a bioactive sesquiterpene, induces G2/M cell cycle arrest and apoptosis in leukemia cells via a Fas- and mitochondria-mediated pathway

scientific article published on January 2007

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scholarly article

1 reference

Europe PubMed Central

18 September 2017

Zerumbone, a bioactive sesquiterpene, induces G2/M cell cycle arrest and apoptosis in leukemia cells via a Fas- and mitochondria-mediated pathway (English)

1 reference

Europe PubMed Central

18 September 2017

1 reference

based on heuristic

inferred from title

Hajime Ohigashi

8

object named as

Hajime Ohigashi

1 reference

Europe PubMed Central

18 September 2017

7

object named as

Akira Murakami

1 reference

Europe PubMed Central

18 September 2017

author name string

Mingji Xian

1

1 reference

Europe PubMed Central

18 September 2017

Keisuke Ito

2

1 reference

Europe PubMed Central

18 September 2017

Tomonori Nakazato

3

1 reference

Europe PubMed Central

18 September 2017

Takatsune Shimizu

4

1 reference

Europe PubMed Central

18 September 2017

Chien-Kang Chen

5

1 reference

Europe PubMed Central

18 September 2017

Kenji Yamato

6

1 reference

Europe PubMed Central

18 September 2017

Yasuo Ikeda

9

1 reference

Europe PubMed Central

18 September 2017

Masahiro Kizaki

10

1 reference

Europe PubMed Central

18 September 2017

publication date

1 January 2007

1 reference

Europe PubMed Central

18 September 2017

1 reference

Europe PubMed Central

18 September 2017

98

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Europe PubMed Central

18 September 2017

1

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Europe PubMed Central

18 September 2017

118-126

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18 September 2017

Identification of zerumbone in Zingiber zerumbet Smith as a potent inhibitor of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha,beta-unsaturated carbonyl group is a prerequisite.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary zerumbone isolated from Zingiber zerumbet

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Suppression of dextran sodium sulfate-induced colitis in mice by zerumbone, a subtropical ginger sesquiterpene, and nimesulide: separately and in combination.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-gamma-induced IkappaB degradation in RAW264.7 macrophages

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Antitumor effects of zerumbone from Zingiber zerumbet in P-388D1 cells in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Death receptor-induced cell killing

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Pro-caspase-3 is a major physiologic target of caspase-8.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Mitochondrial permeability transition is a central coordinating event of apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

The biochemistry of apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Caspases: intracellular signaling by proteolysis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Eat to live, not live to eat.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Caffeine induces G2/M arrest and apoptosis via a novel p53-dependent pathway in NB4 promyelocytic leukemia cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Induction of apoptosis in human myeloid leukemic cells by 1'-acetoxychavicol acetate through a mitochondrial- and Fas-mediated dual mechanism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Antitumor activity of extract of Zingiber aromaticum and its bioactive sesquiterpenoid zerumbone

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Cessation of cell proliferation by adjustment of cell redox potential

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Chk1 and Chk2 kinases in checkpoint control and cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Targeting the checkpoint kinases: chemosensitization versus chemoprotection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

The roles of Chk 1 and Chk 2 in hypoxia and reoxygenation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Role of BAX in the apoptotic response to anticancer agents

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Proapoptotic BID is required for myeloid homeostasis and tumor suppression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2006.00362.X

21 January 2018

Identifiers

10.1111/J.1349-7006.2006.00362.X

1 reference

Europe PubMed Central

18 September 2017

1 reference

Europe PubMed Central

18 September 2017

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